Application of Pharmacokinetic Prediction Platforms in the Design of Optimized Anti-Cancer Drugs

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Descriptors of Cytochrome Inhibitors and Useful Machine Learning Based Methods for the Design of Safer Drugs

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hERG toxicity assessment: Useful guidelines for drug design

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Cardiovascular Toxicity Induced by Kinase Inhibitors: Mechanisms and Preclinical Approaches

(2019) Sarah D. Lamore et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Evaluation of the effect of dabrafenib and metabolites on QTc interval in patients with BRAF V600-mutant tumours

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Development of Safe Drugs: The hERG Challenge

(2017) Subha Kalyaanamoorthy et al.   MEDICINAL RESEARCH REVIEWS

Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity

(2015) Rodolpho C. Braga et al.   Molecular Informatics

Risk of Incremental Toxicities and Associated Costs of New Anticancer Drugs: A Meta-Analysis

(2014) Saroj Niraula et al.   JOURNAL OF CLINICAL ONCOLOGY

Predicting Pharmacokinetic Profiles Using in Silico Derived Parameters

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Global cancer statistics

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