Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity

Tuning hERG Out: Antitarget QSAR Models for Drug Development

(2014) Rodolpho Braga et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Cardiac safety assays

(2013) Jordi Heijman et al.   CURRENT OPINION IN PHARMACOLOGY

Drug Discovery Applications for KNIME: An Open Source Data Mining Platform

(2013) Michael P. Mazanetz et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Similarity maps - a visualization strategy for molecular fingerprints and machine-learning methods

(2013) Sereina Riniker et al.   Journal of Cheminformatics

JSME: a free molecule editor in JavaScript

(2013) Bruno Bienfait et al.   Journal of Cheminformatics

Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates

(2012) Dingsheng Wen et al.   JOURNAL OF APPLIED TOXICOLOGY

Does Rational Selection of Training and Test Sets Improve the Outcome of QSAR Modeling?

(2012) Todd M. Martin et al.   Journal of Chemical Information and Modeling

Supplemental Studies for Cardiovascular Risk Assessment in Safety Pharmacology: A Critical Overview

(2011) Sandra Picard et al.   Cardiovascular Toxicology

ChEMBL: a large-scale bioactivity database for drug discovery

(2011) A. Gaulton et al.   NUCLEIC ACIDS RESEARCH

Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research

(2010) Denis Fourches et al.   Journal of Chemical Information and Modeling

The hERG potassium channel and hERG screening for drug-induced torsades de pointes

(2008) Jules C. Hancox et al.   PHARMACOLOGY & THERAPEUTICS