POU2F3 in SCLC: Clinicopathologic and Genomic Analysis With a Focus on Its Diagnostic Utility in Neuroendocrine-Low SCLC

Neuroendocrine differentiation distinguishes basaloid variant of lung squamous cell carcinoma

(2022) Kianoosh Keyhanian et al.   Diagnostic Pathology

Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

(2021) Carl M. Gay et al.   CANCER CELL

A Tuft Cell–Like Signature Is Highly Prevalent in Thymic Squamous Cell Carcinoma and Delineates New Molecular Subsets Among the Major Lung Cancer Histotypes

(2021) Yosuke Yamada et al.   Journal of Thoracic Oncology

Immunohistochemical Detection of Cancer-Testis Antigen PRAME

(2021) Cecilia Lezcano et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Lung neuroendocrine neoplasms: recent progress and persistent challenges

(2021) Natasha Rekhtman   MODERN PATHOLOGY

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

(2020) John T. Poirier et al.   Journal of Thoracic Oncology

MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

(2020) Abbie S. Ireland et al.   CANCER CELL

Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

(2020) Katherine C. Goldfarbmuren et al.   Nature Communications

The rare YAP1 subtype of Small Cell Lung Cancer revisited in a biobank of 39 Circulating Tumour Cell Patient Derived eXplant models (CDX): A brief report

(2020) Sarah M. Pearsall et al.   Journal of Thoracic Oncology

Multiple faces of pulmonary large cell neuroendocrine carcinoma: update with a focus on practical approach to diagnosis

(2020) Marina K. Baine et al.   Translational Lung Cancer Research

Small Cell Lung Carcinoma Subtypes Defined by ASCL1, NEUROD1, POU2F3 and YAP1: Comprehensive Immunohistochemical and Histopathologic Characterization

(2020) Marina K. Baine et al.   Journal of Thoracic Oncology

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics

(2020) Junfang Lyu et al.   Nature Communications

Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer

(2020) Corrin A. Wohlhieter et al.   Cell Reports

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition

(2019) Arnaud Augert et al.   Science Signaling

Tuft cells: From the mucosa to the thymus

(2019) Shir Nevo et al.   IMMUNOLOGY LETTERS

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids

(2019) Saurabh V. Laddha et al.   CANCER RESEARCH

A Semiquantitative Scoring System May Allow Biopsy Diagnosis of Pulmonary Large Cell Neuroendocrine Carcinoma

(2019) Marina K Baine et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Randomized Phase II Study of Paclitaxel plus Alisertib versus Paclitaxel plus Placebo as Second-Line Therapy for SCLC: Primary and Correlative Biomarker Analyses

(2019) Taofeek K. Owonikoko et al.   Journal of Thoracic Oncology

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

(2019) Marcel A. Dammert et al.   Nature Communications

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer

(2018) Yu-Han Huang et al.   GENES & DEVELOPMENT

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

(2018) Julie George et al.   Nature Communications

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

(2018) Lindsey W. Plasschaert et al.   NATURE

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

(2018) Daniel T. Montoro et al.   NATURE

Tuft Cells—Systemically Dispersed Sensory Epithelia Integrating Immune and Neural Circuitry

(2018) Claire E. O'Leary et al.   Annual Review of Immunology

Aurora-A kinase inhibition is synthetic lethal with loss of the RB1 tumor suppressor gene

(2018) Xueqian Gong et al.   Cancer Discovery

The Use of Immunohistochemistry Improves the Diagnosis of Small Cell Lung Cancer and Its Differential Diagnosis. An International Reproducibility Study in a Demanding Set of Cases

(2017) Erik Thunnissen et al.   Journal of Thoracic Oncology

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

(2017) Ahmet Zehir et al.   NATURE MEDICINE

Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies

(2017) Robert J. Cardnell et al.   Oncotarget

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets

(2016) N. Rekhtman et al.   CLINICAL CANCER RESEARCH

Comprehensive genomic profiles of small cell lung cancer

(2015) Julie George et al.   NATURE

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

(2015) J T Poirier et al.   ONCOGENE

Scientific Rationale Supporting the Clinical Development Strategy for the Investigational Aurora A Kinase Inhibitor Alisertib in Cancer

(2015) Huifeng Niu et al.   Frontiers in Oncology

Therapeutic Targeting of Cancers with Loss of PTEN Function

(2014) Lloye Dillon et al.   CURRENT DRUG TARGETS

Chemosensory Brush Cells of the Trachea. A Stable Population in a Dynamic Epithelium

(2013) Cecil J. Saunders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A framework for identification of actionable cancer genome dependencies in small cell lung cancer

(2012) M. L. Sos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase I Clinical Study of Seneca Valley Virus (SVV-001),a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features

(2011) C. M. Rudin et al.   CLINICAL CANCER RESEARCH

Merkel Cell Polyomavirus Expression in Merkel Cell Carcinomas and Its Absence in Combined Tumors and Pulmonary Neuroendocrine Carcinomas

(2009) Klaus J. Busam et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY