Affinity-Based Profiling of the Flavin Mononucleotide Riboswitch

Riboswitches as Drug Targets for Antibiotics

(2021) Vipul Panchal et al.   Antibiotics-Basel

Microsecond Folding of preQ1 Riboswitch and Its Biological Significance Revealed by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy

(2021) Bidyut Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A chemical probe based on the PreQ1 metabolite enables transcriptome-wide mapping of binding sites

(2021) Sumirtha Balaratnam et al.   Nature Communications

Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing

(2020) Jonathan L. Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PEARL-seq: A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions

(2020) Herschel Mukherjee et al.   ACS Chemical Biology

In‐cell NMR of functional riboswitch aptamers in eukaryotic cells

(2020) P. Broft et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin

(2019) Matthew G. Costales et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyacetate and Polycarbonate RNA: Acylating Reagents and Properties

(2019) Maryam Habibian et al.   ORGANIC LETTERS

An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA

(2019) Lapatrada Taemaitree et al.   Nature Communications

Theory and simulations for RNA folding in mixtures of monovalent and divalent cations

(2019) Hung T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chemistry and applications of RNA 2′-OH acylation

(2019) Willem A. Velema et al.   Nature Reviews Chemistry

Optochemical Control of Biological Processes in Cells and Animals

(2018) Nicholas Ankenbruck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Principles for targeting RNA with drug-like small molecules

(2018) Katherine Deigan Warner et al.   NATURE REVIEWS DRUG DISCOVERY

Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems

(2018) Madeline E. Sherlock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life times of metastable states guide regulatory signaling in transcriptional riboswitches

(2018) Christina Helmling et al.   Nature Communications

Structure–Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch

(2018) Quentin Vicens et al.   ACS Chemical Biology

RNA Chemical Proteomics Reveals the N6-Methyladenosine (m6A)-Regulated Protein–RNA Interactome

(2017) A. Emilia Arguello et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy

(2017) Sven Warhaut et al.   NUCLEIC ACIDS RESEARCH

Single-molecule FRET studies on the cotranscriptional folding of a thiamine pyrophosphate riboswitch

(2017) Heesoo Uhm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Riboswitch-Mediated Gene Regulation: Novel RNA Architectures Dictate Gene Expression Responses

(2016) Anna V. Sherwood et al.   Annual Review of Microbiology

Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes

(2016) Cibran Perez-Gonzalez et al.   Frontiers in Chemistry

Photoaffinity labeling in target- and binding-site identification

(2015) Ewan Smith et al.   Future Medicinal Chemistry

Chemical Mutagenesis of an Emissive RNA Alphabet

(2015) Alexander R. Rovira et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective small-molecule inhibition of an RNA structural element

(2015) John A. Howe et al.   NATURE

Progress and challenges for chemical probing of RNA structure inside living cells

(2015) Miles Kubota et al.   Nature Chemical Biology

Structural analysis of a class III preQ1riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics

(2015) Joseph A. Liberman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Riboswitches: still a lot of undiscovered country

(2015) Robert T. Batey   RNA

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

The rise of regulatory RNA

(2014) Kevin V. Morris et al.   NATURE REVIEWS GENETICS

A Decade of Riboswitches

(2013) Alexander Serganov et al.   CELL

Three-state mechanism couples ligand and temperature sensing in riboswitches

(2013) Anke Reining et al.   NATURE

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

(2012) Jean Guy LeBlanc et al.   CURRENT OPINION IN BIOTECHNOLOGY

Activity-based protein profiling: an enabling technology in chemical biology research

(2012) Nan Li et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Photochemical Control of RNA Structure by Disrupting π-Stacking

(2012) Marino J. E. Resendiz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Long Noncoding RNAs with snoRNA Ends

(2012) Qing-Fei Yin et al.   MOLECULAR CELL

Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch

(2012) Aiming Ren et al.   NATURE

RNA SHAPE analysis in living cells

(2012) Robert C Spitale et al.   Nature Chemical Biology

Prospects for Riboswitch Discovery and Analysis

(2011) Ronald R. Breaker   MOLECULAR CELL

Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation

(2011) Anton Wutz   NATURE REVIEWS GENETICS

Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection

(2011) Quentin Vicens et al.   NUCLEIC ACIDS RESEARCH

Activity-based probes: discovering new biology and new drug targets

(2010) William P. Heal et al.   CHEMICAL SOCIETY REVIEWS

Real-time multidimensional NMR follows RNA folding with second resolution

(2010) M.-K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression

(2010) Elaine R. Lee et al.   RNA Biology

Riboswitches: Structures and Mechanisms

(2010) A. D. Garst et al.   Cold Spring Harbor Perspectives in Biology

Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch

(2009) Alexander Serganov et al.   NATURE

Targeting RNA with Small Molecules

(2008) Jason R. Thomas et al.   CHEMICAL REVIEWS