Enantio- and Regioselective Ni-Catalyzed para-C–H Alkylation of Pyridines with Styrenes via Intermolecular Hydroarylation

Metal-catalyzed asymmetric heteroarylation of alkenes: diverse activation mechanisms

(2022) Shenghan Teng et al.   CHEMICAL SOCIETY REVIEWS

Low‐Temperature Ni‐Catalyzed C−N Cross‐Coupling via Kinetic Resolution Enabled by a Bulky yet Flexible, Chiral N‐Heterocyclic Carbene

(2021) Zi-Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridine Derivatives as Biologically Active Precursors; Organics and Selected Coordination Complexes

(2021) Ezzat Khan   ChemistrySelect

Enantioconvergent Arylation of Racemic Secondary Alcohols to Chiral Tertiary Alcohols Enabled by Nickel/N-Heterocyclic Carbene Catalysis

(2021) Yuan Cai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A radical approach for the selective C–H borylation of azines

(2021) Ji Hye Kim et al.   NATURE

Construction 7-membered ring via Ni–Al bimetal-enabled C–H cyclization for synthesis of tricyclic imidazoles

(2021) Jiang-Fei Li et al.   Nature Communications

Chemo- and Enantioselective Arylation and Alkenylation of Aldehydes Enabled by Nickel/ N -Heterocyclic Carbene Catalysis

(2021) Zi-Chao Wang et al.   CCS Chemistry

Enantioselective Ni/N-Heterocyclic Carbene-Catalyzed Redox-Economical Coupling of Aldehydes, Alkynes, and Enones for Rapid Construction of Acyclic All-Carbon Quaternary Stereocenters

(2021) Wu-Bin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cp*Co(III)-Catalyzed Enantioselective Hydroarylation of Unactivated Terminal Alkenes via C–H Activation

(2021) Yan-Hua Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A directive Ni catalyst overrides conventional site selectivity in pyridine C–H alkenylation

(2021) Tao Zhang et al.   Nature Chemistry

The Expanding Role of Pyridine and Dihydropyridine Scaffolds in Drug Design

(2021) Yong Ling et al.   Drug Design Development and Therapy

Nickel/NHC‐Catalyzed Enantioselective Cyclization of Pyridones and Pyrimidones with Tethered Alkenes

(2020) Di Shen et al.   ADVANCED SYNTHESIS & CATALYSIS

Mechanism and Origin of MAD‐Induced Ni/NHC Catalyzed Regio‐ and Enantioselective C–H Cyclization of Pyridines with Alkenes

(2020) Xia Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel-catalysed anti-Markovnikov hydroarylation of unactivated alkenes with unactivated arenes facilitated by non-covalent interactions

(2020) Noam I. Saper et al.   Nature Chemistry

Enantioselective Twofold C‐H Annulation of Formamides and Alkynes without Built‐in Chelating Groups

(2020) Hao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Insights into the Regioselectivity of Hydroheteroarylation of Allylbenzene with Pyridine Catalyzed by Ni/AlMe3 with N-Heterocyclic Carbene: The Concerted Hydrogen Transfer Mechanism

(2020) Phiphob Naweephattana et al.   JOURNAL OF ORGANIC CHEMISTRY

Fast Enantio‐ and Chemoselective Arylation of Ketones with Organoboronic Esters Enabled by Nickel/N‐Heterocyclic Carbene Catalysis

(2020) Yuan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Enantioselective C–H Cyclization of Pyridines with Alkenes Enabled by a Nickel/N-Heterocyclic Carbene Catalysis

(2019) Wu-Bin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bulky Chiral N-Heterocyclic Carbene Nickel Catalyst Enables Enantioselective C-H Functionalizations of Indoles and Pyrroles

(2019) Johannes Diesel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

meta-Selective C–H Borylation of Benzamides and Pyridines by an Iridium–Lewis Acid Bifunctional Catalyst

(2019) Lichen Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel/NHC-Catalyzed Asymmetric C-H Alkylation of Fluoroarenes with Alkenes: Synthesis of Enantioenriched Fluorotetralins

(2019) Yuan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki–Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers

(2019) Di Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral N-Heterocyclic Carbene Ligands Enable Asymmetric C-H Bond Functionalization

(2019) Olivier Baslé et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Enantioselective Markovnikov Protoboration of α-Olefins Enabled by a Buttressed N-Heterocyclic Carbene Ligand

(2018) Yuan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Ni–Al Bimetallic Catalyzed exo-Selective C–H Cyclization of Imidazoles with Alkenes

(2018) Yin-Xia Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Enantioselective Pyridone C–H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand

(2018) Johannes Diesel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct ortho-C–H Aminoalkylation of 2-Substituted Pyridine Derivatives Catalyzed by Yttrium Complexes with N,N′-Diarylethylenediamido Ligands

(2018) Abhinanda Kundu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cu-Catalyzed 1,4-Dearomatization of Pyridines and Pyridazines without Preactivation of the Heterocycle or Nucleophile

(2018) Michael W. Gribble et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed C–H Oxidative Addition

(2018) Simon Grélaud et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

(2018) Tyler G. Saint-Denis et al.   SCIENCE

Catalytic enantioselective Minisci-type addition to heteroarenes

(2018) Rupert S. J. Proctor et al.   SCIENCE

Recent advances in Ni−Al bimetallic catalysis for unreactive bond transformation

(2018) Yin-Xia Wang et al.   Science China-Chemistry

Enantioselective Aluminum-Free Alkene Hydroarylations through C−H Activation by a Chiral Nickel/JoSPOphos Manifold

(2018) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Cobalt(III)-Catalyzed C−H Activation Enabled by Chiral Carboxylic Acid Cooperation

(2018) Fabio Pesciaioli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel/N-Heterocyclic Carbene Complex-Catalyzed Enantioselective Redox-Neutral Coupling of Benzyl Alcohols and Alkynes to Allylic Alcohols

(2018) Yuan Cai et al.   ACS Catalysis

Mild and Regioselective Benzylic C–H Functionalization: Ni-Catalyzed Reductive Arylation of Remote and Proximal Olefins

(2017) Yuli He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aromatic C–H σ-Bond Activation by Ni0, Pd0, and Pt0 Alkene Complexes: Concerted Oxidative Addition to Metal vs Ligand-to-Ligand H Transfer Mechanism

(2017) Shuwei Tang et al.   ORGANOMETALLICS

Nickel-Catalyzed Hydroacylation of Styrenes with Simple Aldehydes: Reaction Development and Mechanistic Insights

(2016) Li-Jun Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Alkylation of N-Sulfonylbenzamides with Vinyl Ethers via C–H Bond Activation Catalyzed by Hydroxoiridium/Chiral Diene Complexes

(2016) Miyuki Hatano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

para-Selective Alkylation of Benzamides and Aromatic Ketones by Cooperative Nickel/Aluminum Catalysis

(2016) Shogo Okumura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chromium-Catalyzed Regioselective Hydropyridination of Styrenes

(2016) Yuexuan Li et al.   ORGANOMETALLICS

Nickel-catalysed para-CH activation of pyridine with switchable regioselective hydroheteroarylation of allylarenes

(2015) Wei-Chih Lee et al.   CHEMICAL COMMUNICATIONS

Alcohols as alkylating agents in heteroarene C–H functionalization

(2015) Jian Jin et al.   NATURE

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rh(I)–Bisphosphine-Catalyzed Asymmetric, Intermolecular Hydroheteroarylation of α-Substituted Acrylate Derivatives

(2014) Claire M. Filloux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C–H Bond Addition of Pyridines to Alkenes Catalyzed by Chiral Half-Sandwich Rare-Earth Complexes

(2014) Guoyong Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Linear-Selective Hydroarylation of Unactivated Terminal and Internal Olefins with Trifluoromethyl-Substituted Arenes

(2014) Joseph S. Bair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed C4-Selective Direct Alkylation of Pyridines

(2013) Takashi Andou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-complexes of optically active amino- and imino-based pyridine ligands in asymmetric catalysis

(2013) Giorgio Chelucci   COORDINATION CHEMISTRY REVIEWS

The geometry and electronic structure of Aristolochic acid: possible implications for a frozen resonance

(2013) Sergio Manzetti et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

Iridium-Catalyzed Intermolecular Asymmetric Hydroheteroarylation of Bicycloalkenes

(2013) Christo S. Sevov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical-Based Regioselective C–H Functionalization of Electron-Deficient Heteroarenes: Scope, Tunability, and Predictability

(2013) Fionn O’Hara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tandem Isomerization and C–H Activation: Regioselective Hydroheteroarylation of Allylarenes

(2013) Wei-Chih Lee et al.   ORGANIC LETTERS

Pd-catalyzed oxidative C–H/C–H cross-coupling of pyridines with heteroarenes

(2013) Bo Liu et al.   Chemical Science

Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition to N-Activated Pyridines

(2012) James A. Bull et al.   CHEMICAL REVIEWS

Multiwfn: A multifunctional wavefunction analyzer

(2011) Tian Lu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Ligand-Promoted C-3 Selective C–H Olefination of Pyridines with Pd Catalysts

(2011) Mengchun Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rare-Earth-Catalyzed C–H Bond Addition of Pyridines to Olefins

(2011) Bing-Tao Guan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrofluoroarylation of Alkynes with Ni Catalysts. C–H Activation via Ligand-to-Ligand Hydrogen Transfer, an Alternative to Oxidative Addition

(2011) Julie Guihaumé et al.   ORGANOMETALLICS

Transition-Metal-Catalyzed C-H Functionalization for the Synthesis of Substituted Pyridines

(2011) Yoshiaki Nakao   SYNTHESIS-STUTTGART

Selective C-4 Alkylation of Pyridine by Nickel/Lewis Acid Catalysis

(2010) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bimetallic Nickel Aluminun MediatedPara-Selective Alkenylation of Pyridine: Direct Observation of η2,η1-Pyridine Ni(0)−Al(III) Intermediates Prior to C−H Bond Activation

(2010) Chung-Chih Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir-catalyzed highly selective addition of pyridyl C–H bonds to aldehydes promoted by triethylsilane

(2010) Bi-Jie Li et al.   Chemical Science

A Strategy for C−H Activation of Pyridines:  Direct C-2 Selective Alkenylation of Pyridines by Nickel/Lewis Acid Catalysis

(2008) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY