Analytical and preformulation characterization studies of human papillomavirus virus-like particles to enable quadrivalent multi-dose vaccine formulation development

Development of a new, simple, rapid ultra-high-performance liquid chromatography (UHPLC) method for the quantification of 2-phenoxyethanol in vaccines for human use

(2021) Valeria Esposito et al.   BIOLOGICALS

Quantification of trivalent non-replicating rotavirus vaccine antigens in the presence of aluminum adjuvant

(2021) David McAdams et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a register-based observational study

(2021) Milena Falcaro et al.   LANCET

HPV Vaccination and the Risk of Invasive Cervical Cancer

(2020) Jiayao Lei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Capsid destabilization and epitope alterations of human papillomavirus 18 in the presence of thimerosal

(2020) Xiaofen Huang et al.   Journal of Pharmaceutical Analysis

Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens

(2020) Nishant Sawant et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine

(2020) Kawaljit Kaur et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Evaluation of impact of temperature and pH alterations on the size and antigenicity of meningococcal serogroup A and X polysaccharides and conjugates

(2019) Nitya Sharma et al.   VACCINE

Inhibition ELISA as a putative tool for the identification and quantification of meningococcal A and X polysaccharides at various stages of vaccine development

(2019) Nitya Sharma et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Altered antigenicity and immunogenicity of human papillomavirus virus-like particles in the presence of thimerosal

(2019) Siyi Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Recombinant Subunit Rotavirus Trivalent Vaccine Candidate: Physicochemical Comparisons and Stability Evaluations of Three Protein Antigens

(2019) Sanjeev Agarwal et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Current challenges in biotherapeutic particles manufacturing

(2019) Mafalda G. Moleirinho et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Current status of human papillomavirus vaccination in India's cervical cancer prevention efforts

(2019) Rengaswamy Sankaranarayanan et al.   LANCET ONCOLOGY

Protein-Excipient Interactions Evaluated via Nuclear Magnetic Resonance Studies in Polysorbate-Based Multidose Protein Formulations: Influence on Antimicrobial Efficacy and Potential Study Approach

(2018) Riccardo Torosantucci et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Structural Characterization and Formulation Development of a Trivalent Equine Encephalitis Virus-Like Particle Vaccine Candidate

(2018) Vishal M. Toprani et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The impact of 10 years of human papillomavirus (HPV) vaccination in Australia: what additional disease burden will a nonavalent vaccine prevent?

(2018) Cyra Patel et al.   Eurosurveillance

Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want

(2018) Harm HogenEsch et al.   npj Vaccines

Correlating the Effects of Antimicrobial Preservatives on Conformational Stability, Aggregation Propensity, and Backbone Flexibility of an IgG1 mAb

(2017) Jayant Arora et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Characterization of an Escherichia coli -derived human papillomavirus type 16 and 18 bivalent vaccine

(2017) Ying Gu et al.   VACCINE

The complexity and cost of vaccine manufacturing – An overview

(2017) Stanley Plotkin et al.   VACCINE

Doses per vaccine vial container: An understated and underestimated driver of performance that needs more evidence

(2017) Alexis Heaton et al.   VACCINE

Quantitative and epitope-specific antigenicity analysis of the human papillomavirus 6 capsid protein in aqueous solution or when adsorbed on particulate adjuvants

(2016) Min Li et al.   VACCINE

Manufacturing costs of HPV vaccines for developing countries

(2016) Chaevia Clendinen et al.   VACCINE

Role of Benzyl Alcohol in the Unfolding and Aggregation of Interferon α-2a

(2015) Regina L. Bis et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Interactions Between Peptide and Preservatives: Effects on Peptide Self-Interactions and Antimicrobial Efficiency In Aqueous Multi-Dose Formulations

(2015) P. Heljo et al.   PHARMACEUTICAL RESEARCH

Antimicrobial preservatives induce aggregation of interferon alpha-2a: The order in which preservatives induce protein aggregation is independent of the protein

(2014) Regina L. Bis et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Knowledge and Awareness of HPV Vaccine and Acceptability to Vaccinate in Sub-Saharan Africa: A Systematic Review

(2014) Stacey Perlman et al.   PLoS One

Vaccine adjuvant formulations: A pharmaceutical perspective

(2013) Luis A. Brito et al.   SEMINARS IN IMMUNOLOGY

Heterogeneity in liquid shaken cultures of Aspergillus niger inoculated with melanised conidia or conidia of pigmentation mutants

(2013) G.J. van Veluw et al.   STUDIES IN MYCOLOGY

Cervical Cancer Burden and Prevention Strategies: Asia Oceania Perspective

(2012) S. M. Garland et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Preformulation Characterization of an Aluminum Salt-Adjuvanted Trivalent Recombinant Protein-Based Vaccine Candidate Against Streptococcus Pneumoniae

(2012) Vidyashankara Iyer et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Disassembly and reassembly improves morphology and thermal stability of human papillomavirus type 16 virus-like particles

(2012) Qinjian Zhao et al.   Nanomedicine-Nanotechnology Biology and Medicine

Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

(2012) Qinjian Zhao et al.   Virology Journal

Comparison of Compendial Antimicrobial Effectiveness Tests: A Review

(2011) Cheryl L. Moser et al.   AAPS PHARMSCITECH

Flow cytometry: An alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant

(2011) Mildred Ugozzoli et al.   ANALYTICAL BIOCHEMISTRY

Mechanisms of m-cresol-induced Protein Aggregation Studied Using a Model Protein Cytochrome c

(2011) Surinder M. Singh et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Preservative of choice for Prev(e)nar 13™ in a multi-dose formulation

(2011) Lakshmi Khandke et al.   VACCINE

Virus-like particles in vaccine development

(2010) António Roldão et al.   Expert Review of Vaccines

Molecular and structural characterization of the L1 virus-like particles that are used as vaccine antigens inCervarix™, the AS04-adjuvanted HPV-16 and -18 cervical cancer vaccine

(2010) Michel Deschuyteneer et al.   Human vaccines & immunotherapeutics

Preformulation studies—The next advance in aluminum adjuvant-containing vaccines

(2010) Stanley L. Hem et al.   VACCINE

Opportunities and challenges of developing thermostable vaccines

(2009) Dexiang Chen et al.   Expert Review of Vaccines

Development of a Direct Alhydrogel Formulation Immunoassay (DAFIA)

(2009) Daming Zhu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Mercury, Vaccines, and Autism

(2008) Jeffrey P. Baker   AMERICAN JOURNAL OF PUBLIC HEALTH

Interaction of thimerosal with proteins—ethylmercuryadduct formation of human serum albumin and β-lactoglobulin A

(2008) Stefan Trümpler et al.   Metallomics