Pyroptosis may play a crucial role in modifications of the immune microenvironment in periodontitis

Study on the role of pyroptosis in bone resorption induced by occlusal trauma with or without periodontitis

(2022) Mengyang Jiang et al.   JOURNAL OF PERIODONTAL RESEARCH

The immune microenvironment in gastric adenocarcinoma

(2022) Yana Zavros et al.   Nature Reviews Gastroenterology & Hepatology

Channelling inflammation: gasdermins in physiology and disease

(2021) Xing Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis

(2021) Qin Chen et al.   Frontiers in Cell and Developmental Biology

Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study

(2021) María Fernández et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Differential DNA methylation and mRNA transcription in gingival tissues in periodontal health and disease

(2021) Hyunjin Kim et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

The miR-223-3p Regulates Pyroptosis Through NLRP3-Caspase 1-GSDMD Signal Axis in Periodontitis

(2021) Yiru Xia et al.   INFLAMMATION

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis

(2021) Lulu Wang et al.   Journal of Oral Microbiology

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

(2020) Zhibin Zhang et al.   NATURE

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis

(2020) Fernanda R G. Rocha et al.   Scientific Reports

Metformin ameliorates the NLPP3 inflammasome mediated pyroptosis by inhibiting the expression of NEK7 in diabetic periodontitis

(2020) Xinyi Zhou et al.   ARCHIVES OF ORAL BIOLOGY

ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis

(2020) Johannes Griss et al.   MOLECULAR & CELLULAR PROTEOMICS

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

(2019) Mengjiao Wu et al.   EBioMedicine

Caspase 3 may participate in the anti-tumor immunity of dendritic cells

(2019) Jinqiang Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Determining cell type abundance and expression from bulk tissues with digital cytometry

(2019) Aaron M. Newman et al.   NATURE BIOTECHNOLOGY

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

NLRP3: A promising therapeutic target for autoimmune diseases

(2018) Hui-Hui Shen et al.   AUTOIMMUNITY REVIEWS

Development and validation of an immune gene-set based Prognostic signature in ovarian cancer

(2018) Sipeng Shen et al.   EBioMedicine

Role of pyroptosis in cardiovascular diseases

(2018) Chang Jia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions

(2017) Robin A. Aglietti et al.   TRENDS IN IMMUNOLOGY

NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies

(2017) Limin Song et al.   Frontiers in Cellular Neuroscience

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes

(2015) Razvan Cristescu et al.   NATURE MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Molecular aspects of the pathogenesis of periodontitis

(2015) Joerg Meyle et al.   PERIODONTOLOGY 2000

ImmPort: disseminating data to the public for the future of immunology

(2014) Sanchita Bhattacharya et al.   IMMUNOLOGIC RESEARCH

Gingival Tissue Transcriptomes Identify Distinct Periodontitis Phenotypes

(2014) M. Kebschull et al.   JOURNAL OF DENTAL RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Oral Bacteria and Cancer

(2014) Sarah E. Whitmore et al.   PLoS Pathogens

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Mobile Microbiome

(2013) Y.W. Han et al.   JOURNAL OF DENTAL RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

“Gum Bug, Leave My Heart Alone!”—Epidemiologic and Mechanistic Evidence Linking Periodontal Infections and Atherosclerosis

(2010) M. Kebschull et al.   JOURNAL OF DENTAL RESEARCH

Periodontitis: a polymicrobial disruption of host homeostasis

(2010) Richard P. Darveau   NATURE REVIEWS MICROBIOLOGY

Periodontitis in RA—the citrullinated enolase connection

(2010) Karin Lundberg et al.   Nature Reviews Rheumatology

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Targeted Cleavage of Signaling Proteins by Caspase 3 Inhibits T Cell Receptor Signaling in Anergic T Cells

(2008) Irene Puga et al.   IMMUNITY

Transcriptomes in Healthy and Diseased Gingival Tissues

(2008) Ryan T Demmer et al.   JOURNAL OF PERIODONTOLOGY