Sagittaria sagittifolia polysaccharide protects against six-heavy-metal-induced hepatic injury associated with the activation of Nrf2 pathway to regulate oxidative stress and apoptosis

Role of Clusterin/NF-κB in the secretion of senescence-associated secretory phenotype in Cr(VI)-induced premature senescent L-02 hepatocytes

(2021) Yuehui Liang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cr (VI) induces abnormalities in glucose and lipid metabolism through ROS/Nrf2 signaling

(2021) Xiaohong Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Toxicological effects of deltamethrin on quail cerebrum: Weakened antioxidant defense and enhanced apoptosis

(2021) Jiayi Li et al.   ENVIRONMENTAL POLLUTION

Comparison of characterization, antioxidant and immunological activities of three polysaccharides from Sagittaria sagittifolia L.

(2020) Jinyan Gu et al.   CARBOHYDRATE POLYMERS

Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney

(2020) Elpida Poulaki et al.   Scientific Reports

Purification, characterization, antioxidant and immunological activity of polysaccharide from Sagittaria sagittifolia L.

(2020) Jinyan Gu et al.   FOOD RESEARCH INTERNATIONAL

Sagittaria sagittifolia polysaccharide interferes with arachidonic acid metabolism in non-alcoholic fatty liver disease mice via Nrf2/HO-1 signaling pathway

(2020) Xinqi Deng et al.   BIOMEDICINE & PHARMACOTHERAPY

Exploring the liver fibrosis induced by deltamethrin exposure in quails and elucidating the protective mechanism of resveratrol

(2020) Siyu Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cadmium-stimulated invasion of rat liver cells during malignant transformation: Evidence of the involvement of oxidative stress/TET1-sensitive machinery

(2020) Masayo Hirao-Suzuki et al.   TOXICOLOGY

Cadmium contamination in agricultural soils of China and the impact on food safety

(2019) Peng Wang et al.   ENVIRONMENTAL POLLUTION

Glutathione Might Attenuate Cadmium-Induced Liver Oxidative Stress and Hepatic Stellate Cell Activation

(2019) Longfei Ren et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Influence of ferulic acid consumption in ameliorating the cadmium-induced liver and renal oxidative damage in rats

(2019) Sanasam Sanjeev et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Malus micromalus Makino phenolic extract preserves hepatorenal function by regulating PKC-α signaling pathway and attenuating endoplasmic reticulum stress in lead (II) exposure mice

(2019) Guangliang Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cadmium Induces Acute Liver Injury by Inhibiting Nrf2 and the Role of NF-κB, NLRP3, and MAPKs Signaling Pathway

(2019) Chang Liu et al.   International Journal of Environmental Research and Public Health

Alterations of mitochondrial antioxidant indexes and apoptosis in duck livers caused by Molybdenum or/and cadmium

(2018) Xueyan Dai et al.   CHEMOSPHERE

Protective effects of proanthocyanidins against cadmium-induced testicular injury through the modification of Nrf2-Keap1 signal path in rats

(2018) Liu He et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Sagittaria sagittifolia polysaccharide protects against isoniazid- and rifampicin-induced hepatic injury via activation of nuclear factor E2-related factor 2 signaling in mice

(2018) Jing Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis

(2018) Zhong-Gui Gong et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Assessment of phytotoxicity, environmental and health risks of historical urban park soils

(2018) Martin Brtnický et al.   CHEMOSPHERE

Toxic effects of copper on liver and cholinesterase of Clarias gariepinus

(2017) Siti Nadzirah Padrilah et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Selenium triggers Nrf2-mediated protection against cadmium-induced chicken hepatocyte autophagy and apoptosis

(2017) Cong Zhang et al.   TOXICOLOGY IN VITRO

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Possible antioxidant effect of Lycium barbarum polysaccharides on hepatic cadmium-induced oxidative stress in rats

(2016) Maria Vittoria Varoni et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Combined toxicity of heavy metal mixtures in liver cells

(2016) Xialu Lin et al.   JOURNAL OF APPLIED TOXICOLOGY

Restoration of autophagy by puerarin in lead-exposed primary rat proximal tubular cells via regulating AMPK-mTOR signaling

(2016) Xiangbin Song et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Grape seed proanthocyanidins protects against cadmium induced oxidative pancreatitis in rats by attenuating oxidative stress, inflammation and apoptosis via Nrf-2/HO-1 signaling

(2016) Nazima Bashir et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Curcumin improves episodic memory in cadmium induced memory impairment through inhibition of acetylcholinesterase and adenosine deaminase activities in a rat model

(2016) Ayodele Jacob Akinyemi et al.   METABOLIC BRAIN DISEASE

Genistein alleviates lead-induced neurotoxicity in vitro and in vivo : Involvement of multiple signaling pathways

(2016) Peng Su et al.   NEUROTOXICOLOGY

Inhibition of Nickel Nanoparticles-Induced Toxicity by Epigallocatechin-3-Gallate in JB6 Cells May Be through Down-Regulation of the MAPK Signaling Pathways

(2016) Yuanliang Gu et al.   PLoS One

Cadmium overkill: autophagy, apoptosis and necrosis signalling in endothelial cells exposed to cadmium

(2015) Barbara Messner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cadmium exposure during lactation causes learning and memory-impairment in F1 generation mice: amelioration by quercetin

(2015) Sumita Halder et al.   DRUG AND CHEMICAL TOXICOLOGY

Combined exposure to nano-silica and lead induced potentiation of oxidative stress and DNA damage in human lung epithelial cells

(2015) Chun-Feng Lu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Insight into the oxidative stress induced by lead and/or cadmium in blood, liver and kidneys

(2015) Vesna Matović et al.   FOOD AND CHEMICAL TOXICOLOGY

Physicochemical properties of native and γ-irradiated wild arrowhead (Sagittaria sagittifolia L.) tuber starch

(2015) Arif Ali Wani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Toxicity assessment due to sub-chronic exposure to individual and mixtures of four toxic heavy metals

(2015) Samuel J. Cobbina et al.   JOURNAL OF HAZARDOUS MATERIALS

Protective effects of selenium against cadmium induced hematological disturbances, immunosuppressive, oxidative stress and hepatorenal damage in rats

(2015) Mohamed E. El-Boshy et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion

(2013) Shuang Gao et al.   FOOD AND CHEMICAL TOXICOLOGY

NRF2 Protection against Liver Injury Produced by Various Hepatotoxicants

(2013) Jie Liu et al.   Oxidative Medicine and Cellular Longevity

Exposure to As, Cd and Pb-mixture impairs myelin and axon development in rat brain, optic nerve and retina

(2013) Nagendra Kumar Rai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Therapeutic efficacy of silymarin from milk thistle in reducing manganese-induced hepatic damage and apoptosis in rats

(2012) Y Chtourou et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Manganese induces p21 expression in PC12 cells at the transcriptional level

(2012) F. Zhao et al.   NEUROSCIENCE

Nrf2 activation prevents cadmium-induced acute liver injury

(2012) Kai C. Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Phospholipase C Mediates Cadmium-Dependent Apoptosis in HEK 293 Cells

(2011) Akeem O. Lawal et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Studies on the antioxidant and hepatoprotective activities of polysaccharides from Talinum triangulare

(2011) Dong Liang et al.   JOURNAL OF ETHNOPHARMACOLOGY

An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays

(2010) Thomas E. Gunter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Manganese-induced single strand breaks of mitochondrial DNA in vitro and in vivo

(2008) Jian Jiao et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY