Early-Phase Oncology Trials: Why So Many Designs?

Phase I clinical trials in adoptive T‐cell therapies

(2021) Sean M. Devlin et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS

The Role of Early-Phase Design—Response

(2019) Mark R. Conaway et al.   CLINICAL CANCER RESEARCH

The Role of Early-Phase Design—Letter

(2019) Mark J. Ratain   CLINICAL CANCER RESEARCH

Semiparametric dose finding methods: special cases

(2018) M. Clertant et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS

The Impact of Early-Phase Trial Design in the Drug Development Process

(2018) Mark R. Conaway et al.   CLINICAL CANCER RESEARCH

Semiparametric dose finding methods

(2017) M. Clertant et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Integrating the escalation and dose expansion studies into a unified Phase I clinical trial

(2016) Alexia Iasonos et al.   Contemporary Clinical Trials

Phase I designs that allow for uncertainty in the attribution of adverse events

(2016) Alexia Iasonos et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS

Incoherent dose-escalation in phase I trials using the escalation with overdose control approach

(2016) Graham M. Wheeler   STATISTICAL PAPERS

A Bayesian adaptive design for estimating the maximum tolerated dose curve using drug combinations in cancer phase I clinical trials

(2016) Mourad Tighiouart et al.   STATISTICS IN MEDICINE

Dimension of model parameter space and operating characteristics in adaptive dose-finding studies

(2016) Alexia Iasonos et al.   STATISTICS IN MEDICINE

Dose Expansion Cohorts in Phase I Trials

(2016) Alexia Iasonos et al.   Statistics in Biopharmaceutical Research

A product of independent beta probabilities dose escalation design for dual-agent phase I trials

(2015) Adrian P. Mander et al.   STATISTICS IN MEDICINE

Adaptive Dose-Finding Studies: A Review of Model-Guided Phase I Clinical Trials

(2014) Alexia Iasonos et al.   JOURNAL OF CLINICAL ONCOLOGY

Bayesian optimal interval designs for phase I clinical trials

(2014) Suyu Liu et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS

Bridging Solutions in Dose-Finding Problems

(2014) John O'Quigley et al.   Statistics in Biopharmaceutical Research

Continual Reassessment Method for Partial Ordering

(2011) Nolan A. Wages et al.   BIOMETRICS

The treatment versus experimentation dilemma in dose finding studies

(2011) D. Azriel et al.   JOURNAL OF STATISTICAL PLANNING AND INFERENCE

A modified toxicity probability interval method for dose-finding trials

(2010) Yuan Ji et al.   Clinical Trials

Bayesian Model Averaging Continual Reassessment Method in Phase I Clinical Trials

(2009) Guosheng Yin et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Unifying CRM and EWOC designs for phase I cancer clinical trials

(2008) Pei-Ling Chu et al.   JOURNAL OF STATISTICAL PLANNING AND INFERENCE