Metformin Attenuates UVA-Induced Skin Photoaging by Suppressing Mitophagy and the PI3K/AKT/mTOR Pathway
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metformin Attenuates UVA-Induced Skin Photoaging by Suppressing Mitophagy and the PI3K/AKT/mTOR Pathway
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 13, Pages 6960
Publisher
MDPI AG
Online
2022-06-24
DOI
10.3390/ijms23136960
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Skin senescence: mechanisms and impact on whole-body aging
- (2022) Ana Catarina Franco et al. TRENDS IN MOLECULAR MEDICINE
- Cyanobacteria Secondary Metabolites as Biotechnological Ingredients in Natural Anti-Aging Cosmetics: Potential to Overcome Hyperpigmentation, Loss of Skin Density and UV Radiation-Deleterious Effects
- (2022) Rita Favas et al. Marine Drugs
- Protective Effect of Djulis (Chenopodium formosanum) Extract against UV- and AGEs-Induced Skin Aging via Alleviating Oxidative Stress and Collagen Degradation
- (2022) Jia-Ling Lyu et al. MOLECULES
- The Function of Metformin in Aging-Related Musculoskeletal Disorders
- (2022) Yanhong Song et al. Frontiers in Pharmacology
- TGFβ Signaling in Photoaging and UV-Induced Skin Cancer
- (2021) Yao Ke et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells
- (2021) Hyoungnae Kim et al. AGING CELL
- Cellular aging beyond cellular senescence: Markers of senescence prior to cell cycle arrest in vitro and in vivo
- (2021) Mikolaj Ogrodnik AGING CELL
- VCP/p97 cofactor UBXN1/SAKS1 regulates mitophagy by modulating MFN2 removal from mitochondria
- (2021) Chantal Mengus et al. Autophagy
- The role of UVA radiation in ketoprofen-mediated BRAF-mutant amelanotic melanoma cells death – A study at the cellular and molecular level
- (2021) Klaudia Banach et al. TOXICOLOGY IN VITRO
- The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis
- (2021) Huey-Jiun Ko et al. Biomolecules
- Molecular mechanisms involved in DNA repair in human cancers: An overview of PI3k/Akt signaling and PIKKs crosstalk
- (2021) Forough Alemi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Histone Acetylation via α7nAChR-Mediated PI3K/Akt Activation and Its Impact on γ-H2AX Generation
- (2021) Mariko Shikata et al. CHEMICAL RESEARCH IN TOXICOLOGY
- PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease
- (2020) Lucia Barazzuol et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence
- (2020) Yongtao Wang et al. Aging-US
- Benefits of Metformin in Attenuating the Hallmarks of Aging
- (2020) Ameya S. Kulkarni et al. Cell Metabolism
- Solar ultraviolet‐induced DNA damage response: Melanocytes story in transformation to environmental melanomagenesis
- (2020) Soumyadeep Sarkar et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Targeting ageing and preventing organ degeneration with metformin
- (2020) Anthony P. Sunjaya et al. DIABETES & METABOLISM
- Astaxanthin protects mesenchymal stem cells from oxidative stress by direct scavenging of free radicals and modulation of cell signaling
- (2020) Solmaz Mohammadi et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Cellular senescence in ageing: from mechanisms to therapeutic opportunities
- (2020) Raffaella Di Micco et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sirt3 Attenuates Oxidative Stress Damage and Rescues Cellular Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Superoxide Dismutase 2
- (2020) Cao Ma et al. Frontiers in Cell and Developmental Biology
- Activation of mTORC1/PGC1 axis promotes mitochondrial biogenesis and induces cellular senescence in the lung epithelium
- (2019) Ross Summer et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- UVA and UVB radiation induce the formation of neutrophil extracellular traps by human polymorphonuclear cells
- (2019) Marcin Zawrotniak et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
- (2019) Shireen A. Sarraf et al. Cell Reports
- mTORC1 pathway in DNA damage response
- (2018) Yinxing Ma et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cancer chemoprevention revisited: Cytochrome P450 family 1B1 as a target in the tumor and the microenvironment
- (2018) Gabriele D'Uva et al. CANCER TREATMENT REVIEWS
- L-carnitine mitigates UVA-induced skin tissue injury in rats through downregulation of oxidative stress, p38/c-Fos signaling, and the proinflammatory cytokines
- (2018) Samir A. Salama et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Mdivi-1 alleviates blood-brain barrier disruption and cell death in experimental traumatic brain injury by mitigating autophagy dysfunction and mitophagy activation
- (2018) Qiong Wu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- N-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter pylori Infection
- (2018) Chuan Xie et al. Oxidative Medicine and Cellular Longevity
- Impaired Proteostasis in Senescent Vascular Endothelial Cells: A Perspective on Estrogen and Oxidative Stress in the Aging Vasculature
- (2018) Hyun-Tae V Hwang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway
- (2018) Hongjun Fan et al. CARCINOGENESIS
- Crosstalk between Phosphoinositide 3-kinase/Akt signaling pathway with DNA damage response and oxidative stress in cancer
- (2018) Ansar Karimian et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Alpha pinene modulates UVA-induced oxidative stress, DNA damage and apoptosis in human skin epidermal keratinocytes
- (2018) Ramasamy Karthikeyan et al. LIFE SCIENCES
- Direct participation of DNA in the formation of singlet oxygen and base damage under UVA irradiation
- (2017) Teiti Yagura et al. FREE RADICAL BIOLOGY AND MEDICINE
- Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner
- (2013) Qing Yang et al. PLoS One
- Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes
- (2012) Jana Jandova et al. EXPERIMENTAL CELL RESEARCH
- Investigating the role of melanin in UVA/UVB- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells
- (2011) Helen Swalwell et al. FREE RADICAL BIOLOGY AND MEDICINE
- Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies
- (2009) Murielle Mimeault et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now