Overexpression of the Bam Complex Improves the Production of Chlamydia trachomatis MOMP in the E. coli Outer Membrane

Sublingual Boosting with A Novel Mucoadhesive Thermogelling Hydrogel Following Parenteral CAF01 Priming as A Strategy Against Chlamydia Trachomatis

(2022) Lorena Garcia‐del Rio et al.   Advanced Healthcare Materials

Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding

(2022) Matthew Thomas Doyle et al.   CELL

Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?

(2021) Luis M. de la Maza et al.   Expert Review of Vaccines

The assembly of β-barrel outer membrane proteins

(2021) David Tomasek et al.   CURRENT OPINION IN MICROBIOLOGY

Chlamydia trachomatis: Cell biology, immunology and vaccination

(2021) Sam M. Murray et al.   VACCINE

Lipoprotein DolP supports proper folding of BamA in the bacterial outer membrane promoting fitness upon envelope stress

(2021) David Ranava et al.   eLife

A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars

(2021) Anja Weinreich Olsen et al.   npj Vaccines

Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras

(2021) Trang H. Phan et al.   Microbial Cell Factories

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP

(2021) Robert W. Harkness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Escherichia coli Outer Membrane β-Barrel Assembly Machinery (BAM) Crosstalks with the Divisome

(2021) Elisa Consoli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Problems With Understanding Chlamydia trachomatis Immunology

(2021) Robert C Brunham   JOURNAL OF INFECTIOUS DISEASES

Th1/Th17 T cell Tissue-Resident Immunity Increases Protection, But Is Not Required in a Vaccine Strategy Against Genital Infection With Chlamydia trachomatis

(2021) Nina Dieu Nhien Tran Nguyen et al.   Frontiers in Immunology

Strategies to Enhance Periplasmic Recombinant Protein Production Yields in Escherichia coli

(2021) Alexandros Karyolaimos et al.   Frontiers in Bioengineering and Biotechnology

Comparison of Chlamydia outer membrane complex to recombinant outer membrane proteins as vaccine

(2020) Hong Yu et al.   VACCINE

Parenteral vaccination protects against transcervical infection with Chlamydia trachomatis and generate tissue-resident T cells post-challenge

(2020) Nina Dieu Nhien Tran Nguyen et al.   npj Vaccines

Protection against a chlamydial respiratory challenge by a chimeric vaccine formulated with the Chlamydia muridarum major outer membrane protein variable domains using the Neisseria lactamica porin B as a scaffold

(2020) Delia F. Tifrea et al.   npj Vaccines

Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA

(2020) Elizabeth M. Hart et al.   JOURNAL OF BACTERIOLOGY

Super-Resolution Fluorescence Microscopy Reveals Clustering Behaviour of Chlamydia pneumoniae’s Major Outer Membrane Protein

(2020) Amy E. Danson et al.   Biology-Basel

Bacterial outer membrane proteins assemble via asymmetric interactions with the BamA β-barrel

(2019) Matthew T. Doyle et al.   Nature Communications

Safety and immunogenicity of the chlamydia vaccine candidate CTH522 adjuvanted with CAF01 liposomes or aluminium hydroxide: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial

(2019) Sonya Abraham et al.   LANCET INFECTIOUS DISEASES

A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522

(2018) Fabrice Rose et al.   JOURNAL OF CONTROLLED RELEASE

Comparing autotransporter β-domain configurations for their capacity to secrete heterologous proteins to the cell surface

(2018) Wouter S. P. Jong et al.   PLoS One

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

(2018) Sachith D. Gunasinghe et al.   Cell Reports

Spectroscopic Analysis of Chlamydial Major Outer Membrane Protein in Support of Structure Elucidation

(2018) Robert W. Hepler et al.   PROTEIN SCIENCE

Cell-free production of a functional oligomeric form of aChlamydiamajor outer-membrane protein (MOMP) for vaccine development

(2017) Wei He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modeling Diversity in Structures of Bacterial Outer Membrane Lipids

(2017) Huilin Ma et al.   Journal of Chemical Theory and Computation

National Institute of Allergy and Infectious Diseases workshop report: “Chlamydia vaccines: The way forward”

(2017) Guangming Zhong et al.   VACCINE

Status of vaccine research and development of vaccines for Chlamydia trachomatis infection

(2017) Taylor B. Poston et al.   VACCINE

Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract

(2017) Jeanette Erbo Wern   Frontiers in Immunology

Recombinant expression of Chlamydia trachomatis major outer membrane protein in E. Coli outer membrane as a substrate for vaccine research

(2016) Zhiyun Wen et al.   BMC MICROBIOLOGY

Chlamydia cell biology and pathogenesis

(2016) Cherilyn Elwell et al.   NATURE REVIEWS MICROBIOLOGY

Protection AgainstChlamydia trachomatisInfection and Upper Genital Tract Pathological Changes by Vaccine-Promoted Neutralizing Antibodies Directed to the VD4 of the Major Outer Membrane Protein

(2015) Anja W. Olsen et al.   JOURNAL OF INFECTIOUS DISEASES

A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

(2015) G. Stary et al.   SCIENCE

Salmonella enterica serovar Typhimurium ΔmsbB Triggers Exacerbated Inflammation in Nod2 Deficient Mice

(2014) Anne-Kathrin Claes et al.   PLoS One

Reconstitution of bacterial autotransporter assembly using purified components

(2014) Giselle Roman-Hernandez et al.   eLife

Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels

(2013) Susan Schlegel et al.   Microbial Cell Factories

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

A 3-Dimensional Trimeric β-Barrel Model for Chlamydia MOMP Contains Conserved and Novel Elements of Gram-Negative Bacterial Porins

(2013) Victoria A. Feher et al.   PLoS One

Chlamydia trachomatis control requires a vaccine

(2013) Robert C. Brunham et al.   VACCINE

Development status and future prospects for a vaccine against Chlamydia trachomatis infection

(2013) Louise M. Hafner et al.   VACCINE

Optimizing Membrane Protein Overexpression in the Escherichia coli strain Lemo21(DE3)

(2012) Susan Schlegel et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamic Association of BAM Complex Modules Includes Surface Exposure of the Lipoprotein BamC

(2012) Chaille T. Webb et al.   JOURNAL OF MOLECULAR BIOLOGY

A novel chimeric MOMP antigen expressed in Escherichia coli, Arabidopsis thaliana, and Daucus carota as a potential Chlamydia trachomatis vaccine candidate

(2011) Irina Kalbina et al.   PROTEIN EXPRESSION AND PURIFICATION

Identification of Chlamydia trachomatis Outer Membrane Complex Proteins by Differential Proteomics

(2010) X. Liu et al.   JOURNAL OF BACTERIOLOGY

Reconstitution of Outer Membrane Protein Assembly from Purified Components

(2010) C. L. Hagan et al.   SCIENCE

β-Barrel Proteins That Reside in theEscherichia coliOuter Membranein VivoDemonstrate Varied Folding Behaviorin Vitro

(2008) Nancy K. Burgess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tuning Escherichia coli for membrane protein overexpression

(2008) S. Wagner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of the membrane-spanning β-strands of the major outer membrane protein of Chlamydia

(2002) María José Rodríguez-Marañón et al.   PROTEIN SCIENCE