Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior

Classic Psychedelic Drugs: Update on Biological Mechanisms

(2022) Franz X. Vollenweider et al.   PHARMACOPSYCHIATRY

Structure-based discovery of nonhallucinogenic psychedelic analogs

(2022) Dongmei Cao et al.   SCIENCE

Effects of ketamine optical isomers, psilocybin, psilocin and norpsilocin on time estimation and cognition in rats

(2022) Piotr Popik et al.   PSYCHOPHARMACOLOGY

Prenatal MAM treatment altered fear conditioning following social isolation: Relevance to schizophrenia

(2021) Wiktor Bilecki et al.   BEHAVIOURAL BRAIN RESEARCH

Trial of Psilocybin versus Escitalopram for Depression

(2021) Robin Carhart-Harris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

(2021) Mingzheng Wu et al.   eLife

Ginsenoside Re Protects against Serotonergic Behaviors Evoked by 2,5-Dimethoxy-4-iodo-amphetamine in Mice via Inhibition of PKCδ-Mediated Mitochondrial Dysfunction

(2021) Eun-Joo Shin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tolerance to neurochemical and behavioral effects of the hallucinogen 25I-NBOMe

(2021) Monika Herian et al.   PSYCHOPHARMACOLOGY

Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice

(2021) Mario de la Fuente Revenga et al.   Cell Reports

Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression

(2020) Meghan Hibicke et al.   ACS Chemical Neuroscience

Mental and somatic comorbidity of depression: a comprehensive cross-sectional analysis of 202 diagnosis groups using German nationwide ambulatory claims data

(2020) Annika Steffen et al.   BMC Psychiatry

Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin

(2020) N. L. Mason et al.   NEUROPSYCHOPHARMACOLOGY

Cortical and raphe GABAA, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine

(2020) Thu Ha Pham et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Cell-type specific modulation of NMDA receptors triggers antidepressant actions

(2020) Santosh Pothula et al.   MOLECULAR PSYCHIATRY

Neurochemical and Behavioral Effects of a New Hallucinogenic Compound 25B-NBOMe in Rats

(2020) Adam Wojtas et al.   NEUROTOXICITY RESEARCH

A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics

(2020) Neil K. Savalia et al.   TRENDS IN NEUROSCIENCES

Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat

(2019) Oskar Jefsen et al.   ACTA NEUROPSYCHIATRICA

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

(2019) Ronald S. Duman et al.   NEURON

Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats

(2019) Monika Herian et al.   NEUROTOXICITY RESEARCH

(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism

(2019) Yukio Ago et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Early-life blockade of NMDA receptors induces epigenetic abnormalities in the adult medial prefrontal cortex: possible involvement in memory impairment in trace fear conditioning

(2019) Joachim Latusz et al.   PSYCHOPHARMACOLOGY

GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions

(2019) Danielle M. Gerhard et al.   JOURNAL OF CLINICAL INVESTIGATION

Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity

(2018) Rachael Ingram et al.   NEUROPHARMACOLOGY

Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine

(2018) Evgeny Pryazhnikov et al.   Scientific Reports

Psychedelics Promote Structural and Functional Neural Plasticity

(2018) Calvin Ly et al.   Cell Reports

Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia

(2018) Marzena Maćkowiak et al.   METABOLIC BRAIN DISEASE

Ketamine for Depression, 1: Clinical Summary of Issues Related to Efficacy, Adverse Effects, and Mechanism of Action

(2017) Chittaranjan Andrade   JOURNAL OF CLINICAL PSYCHIATRY

The effects of ketamine on dopaminergic function: meta-analysis and review of the implications for neuropsychiatric disorders

(2017) M Kokkinou et al.   MOLECULAR PSYCHIATRY

Serotonergic modulation of the activity of mesencephalic dopaminergic systems: Therapeutic implications

(2017) Philippe De Deurwaerdère et al.   PROGRESS IN NEUROBIOLOGY

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

(2017) R. L. Carhart-Harris et al.   PSYCHOPHARMACOLOGY

Sex Differences in Effects of Ketamine on Behavior, Spine Density, and Synaptic Proteins in Socially Isolated Rats

(2016) Ambalika Sarkar et al.   BIOLOGICAL PSYCHIATRY

Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine

(2016) Chao Dong et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

GABA interneurons mediate the rapid antidepressant-like effects of scopolamine

(2016) Eric S. Wohleb et al.   JOURNAL OF CLINICAL INVESTIGATION

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

(2016) Ronald S Duman et al.   NATURE MEDICINE

Presynaptic serotonin 2A receptors modulate thalamocortical plasticity and associative learning

(2016) Alexander Barre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Psilocin on Extracellular Dopamine and Serotonin Levels in the Mesoaccumbens and Mesocortical Pathway in Awake Rats

(2015) Yuichi Sakashita et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Early-life stress increases the survival of midbrain neurons during postnatal development and enhances reward-related and anxiolytic-like behaviors in a sex-dependent fashion

(2015) Agnieszka Chocyk et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Antidepressant Effects of an mGlu2/3 Receptor Antagonist and Ketamine Require AMPA Receptor Stimulation in the mPFC and Subsequent Activation of the 5-HT Neurons in the DRN

(2015) Kenichi Fukumoto et al.   NEUROPSYCHOPHARMACOLOGY

Phencyclidine Inhibits the Activity of Thalamic Reticular Gamma-Aminobutyric Acidergic Neurons in Rat Brain

(2014) Eva Troyano-Rodriguez et al.   BIOLOGICAL PSYCHIATRY

Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia

(2014) David A. Martin et al.   NEUROPHARMACOLOGY

Anxiolytic-like effects of olanzapine, risperidone and fluoxetine in the elevated plus-maze test in rats

(2014) Zofia Rogóż et al.   Pharmacological Reports

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Subanesthetic Doses of Ketamine Transiently Decrease Serotonin Transporter Activity: A PET Study in Conscious Monkeys

(2013) Shigeyuki Yamamoto et al.   NEUROPSYCHOPHARMACOLOGY

Animal Models of Serotonergic Psychedelics

(2012) James B. Hanks et al.   ACS Chemical Neuroscience

Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

(2012) James W. Murrough et al.   BIOLOGICAL PSYCHIATRY

Targeting the Glutamatergic System to Treat Major Depressive Disorder

(2012) Daniel C. Mathews et al.   DRUGS

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens

(2011) Adam L. Halberstadt et al.   NEUROPHARMACOLOGY

Serotonergic projections and serotonin receptor expression in the reticular nucleus of the thalamus in the rat

(2011) José J. RodrÍGuez et al.   SYNAPSE

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

(2008) Sheldon H. Preskorn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY