Standing on the shoulders of mice

Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee

(2022) Stuart G. Tangye et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Modeling human adaptive immune responses with tonsil organoids

(2021) Lisa E. Wagar et al.   NATURE MEDICINE

Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy

(2021) Marieke C. Verweij et al.   SCIENCE

HLA-E–restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities

(2021) Hongbing Yang et al.   Science Immunology

Cytomegaloviral determinants of CD8+ T cell programming and RhCMV/SIV vaccine efficacy

(2021) Daniel Malouli et al.   Science Immunology

Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

(2021) Vivien Béziat et al.   CELL

New-onset IgG autoantibodies in hospitalized patients with COVID-19

(2021) Sarah Esther Chang et al.   Nature Communications

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross

(2020) Matthew D. Martin et al.   Cell Reports

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

(2020) Kelsey E. Noll et al.   Cell Reports

The Role of Tissue-resident γδ T Cells in Stress Surveillance and Tissue Maintenance

(2020) Margarete D. Johnson et al.   Cells

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

(2020) Paul Bastard et al.   SCIENCE

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

Whole Genome Sequencing and Progress Towards Full Inbreeding of the Mouse Collaborative Cross Population

(2019) John R. Shorter et al.   G3-Genes Genomes Genetics

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

(2019) Gianni Monaco et al.   Cell Reports

HIV subtype diversity worldwide

(2019) Nicholas Bbosa et al.   Current Opinion in HIV and AIDS

Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans

(2019) Caroline J. Zeiss et al.   G3-Genes Genomes Genetics

The phagocyte NOX2 NADPH oxidase in microbial killing and cell signaling

(2019) William M Nauseef   CURRENT OPINION IN IMMUNOLOGY

Humanized Mice as Unique Tools for Human-Specific Studies

(2018) Kylie Su Mei Yong et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Skin wound healing in humans and mice: Challenges in translational research

(2018) Helena D. Zomer et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins

(2018) Chung-An M. Wu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

(2018) Eric Shifrut et al.   CELL

Found In Translation: a machine learning model for mouse-to-human inference

(2018) Rachelly Normand et al.   NATURE METHODS

Dynamics of Recent Thymic Emigrants in Young Adult Mice

(2017) Vera van Hoeven et al.   Frontiers in Immunology

The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation

(2016) Rajesh Ravindran et al.   NATURE

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

CD4 + T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion

(2015) Francois P. Legoux et al.   IMMUNITY

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

(2015) Wong Yu et al.   IMMUNITY

Human spleen microanatomy: why mice do not suffice

(2015) Birte S. Steiniger   IMMUNOLOGY

Efficient genetic engineering of human intestinal organoids using electroporation

(2015) Masayuki Fujii et al.   Nature Protocols

Cytomegalovirus infection enhances the immune response to influenza

(2015) David Furman et al.   Science Translational Medicine

Proteases, neutrophils, and periodontitis: the NET effect

(2014) William M. Nauseef   JOURNAL OF CLINICAL INVESTIGATION

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

(2014) Xianqin Zhang et al.   NATURE

Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine

(2013) Anthony Rongvaux et al.   Annual Review of Immunology

Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

(2013) Laura F. Su et al.   IMMUNITY

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

(2013) T. Shay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Status and access to the Collaborative Cross population

(2012) Catherine E. Welsh et al.   MAMMALIAN GENOME

Mycobacterial Disease and Impaired IFN-  Immunity in Humans with Inherited ISG15 Deficiency

(2012) D. Bogunovic et al.   SCIENCE

Regulatory T cells and Foxp3

(2011) Alexander Y. Rudensky   IMMUNOLOGICAL REVIEWS

Ensembl BioMarts: a hub for data retrieval across taxonomic space

(2011) R. J. Kinsella et al.   Database-The Journal of Biological Databases and Curation

Evasion of CD8+ T Cells Is Critical for Superinfection by Cytomegalovirus

(2010) S. G. Hansen et al.   SCIENCE

A Prescription for Human Immunology

(2008) Mark M. Davis   IMMUNITY

The Collaborative Cross, developing a resource for mammalian systems genetics: A status report of the Wellcome Trust cohort

(2008) Fuad A. Iraqi et al.   MAMMALIAN GENOME

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY