Tryptophan-rich diet ameliorates chronic unpredictable mild stress induced depression- and anxiety-like behavior in mice: The potential involvement of gut-brain axis

Fecal microbiota transplantation ameliorates stress-induced depression-like behaviors associated with the inhibition of glial and NLRP3 inflammasome in rat brain

(2021) Jingjing Rao et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress

(2021) Aika Kosuge et al.   BRAIN BEHAVIOR AND IMMUNITY

Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation

(2021) Hai-long Yang et al.   INFLAMMATION

Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat

(2021) Haonan Li et al.   Journal of Neuroinflammation

Akkermansia muciniphila administration exacerbated the development of colitis-associated colorectal cancer in mice

(2021) Fei Wang et al.   Journal of Cancer

MicroRNA134 of Ventral Hippocampus Is Involved in Cocaine Extinction-Induced Anxiety-like and Depression-like Behaviors in Mice

(2020) Yuehan Li et al.   Molecular Therapy-Nucleic Acids

Lycopene Alleviates DSS-Induced Colitis and Behavioral Disorders via Mediating Microbes-Gut–Brain Axis Balance

(2020) Beita Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Updated review of research on the gut microbiota and their relation to depression in animals and human beings

(2020) Zhongli Yang et al.   MOLECULAR PSYCHIATRY

The Role of the Gut Microbiota in Dietary Interventions for Depression and Anxiety

(2020) Tracey L K Bear et al.   Advances in Nutrition

Host–microbiome interactions: the aryl hydrocarbon receptor as a critical node in tryptophan metabolites to brain signaling

(2020) Ning Ma et al.   Gut Microbes

Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor

(2020) Samantha A. Scott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-Fluorouracil induced dysregulation of the microbiome-gut-brain axis manifesting as depressive like behaviors in rats

(2020) Fan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse

(2020) Livia H. Morais et al.   CURRENT BIOLOGY

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

(2020) Grégoire Chevalier et al.   Nature Communications

DIABLO: an integrative approach for identifying key molecular drivers from multi-omic assays

(2019) Amrit Singh et al.   BIOINFORMATICS

The neuroactive potential of the human gut microbiota in quality of life and depression

(2019) Mireia Valles-Colomer et al.   Nature Microbiology

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

(2019) Michael Platten et al.   NATURE REVIEWS DRUG DISCOVERY

Tryptophan Metabolic Pathways and Brain Serotonergic Activity: A Comparative Review

(2019) Erik Höglund et al.   Frontiers in Endocrinology

Systematic Review of Gut Microbiota and Major Depression

(2019) Stephanie G. Cheung et al.   Frontiers in Psychiatry

Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats

(2019) Xue-Mei Han et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Lactobacillus and Bifidobacterium Improves Physiological Function and Cognitive Ability in Aged Mice by the Regulation of Gut Microbiota

(2019) Yinhua Ni et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Tryptophan Dietary Impacts Gut Barrier and Metabolic Diseases

(2019) Soraya Taleb   Frontiers in Immunology

Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior

(2019) Ke-qi Fan et al.   CELL

Supplementation of Sesamin Alleviates Stress-Induced Behavioral and Psychological Disorders via Reshaping the Gut Microbiota Structure

(2019) Qianxu Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Gastrointestinal (non-systemic) antibiotic rifaximin differentially affects chronic stress-induced changes in colon microbiome and gut permeability without effect on behavior

(2019) Dániel Kuti et al.   BRAIN BEHAVIOR AND IMMUNITY

Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

(2018) F. Guida et al.   BRAIN BEHAVIOR AND IMMUNITY

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

(2018) Allison Agus et al.   Cell Host & Microbe

Sucrose preference test for measurement of stress-induced anhedonia in mice

(2018) Meng-Ying Liu et al.   Nature Protocols

Peripheral Serotonin Synthesis as a New Drug Target

(2018) Susann Matthes et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation

(2018) Lige Leng et al.   NEURON

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

A next generation probiotic, Akkermansia muciniphila

(2018) Qixiao Zhai et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Depression

(2018) Gin S Malhi et al.   LANCET

Commensal Escherichia coli Strains Can Promote Intestinal Inflammation via Differential Interleukin-6 Production

(2018) Hatem Kittana et al.   Frontiers in Immunology

Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice

(2017) Jahidul Islam et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Microbiota-derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo

(2017) M. Jennis et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase

(2016) René Fuertig et al.   BRAIN BEHAVIOR AND IMMUNITY

Treatment with a Monoclonal Anti-IL-12p40 Antibody Induces Substantial Gut Microbiota Changes in an Experimental Colitis Model

(2016) Josué Castro-Mejía et al.   Gastroenterology Research and Practice

Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder

(2016) Christopher Newell et al.   Molecular Autism

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

(2016) L Brundin et al.   Translational Psychiatry

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder

(2015) Jonathan Savitz et al.   BRAIN BEHAVIOR AND IMMUNITY

Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet

(2015) Giuseppe Musumeci et al.   BRAIN RESEARCH BULLETIN

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

(2015) Carles Cantó et al.   Cell Metabolism

Antidepressant Effects of TrkB Ligands on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation

(2015) Ji-chun Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress

(2015) S. Liang et al.   NEUROSCIENCE

Review article: intestinal barrier dysfunction and central nervous system disorders - a controversial association

(2014) M. Julio-Pieper et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Correlation between the human fecal microbiota and depression

(2014) A. Naseribafrouei et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

(2014) Jesse S. O. Lindholm et al.   Frontiers in Behavioral Neuroscience

Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications

(2013) J.C. Felger et al.   NEUROSCIENCE

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY