Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity by targeting Nrf2 and NEK7-NLRP3 signaling pathway
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity by targeting Nrf2 and NEK7-NLRP3 signaling pathway
Authors
Keywords
-
Journal
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Volume 241, Issue -, Pages 113773
Publisher
Elsevier BV
Online
2022-06-24
DOI
10.1016/j.ecoenv.2022.113773
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- NLRP3 inflammasome in rosmarinic acid-afforded attenuation of acute kidney injury in mice
- (2022) Juheb Akhter et al. Scientific Reports
- Anti-Inflammatory Effects of Rosmarinic Acid-Loaded Nanovesicles in Acute Colitis through Modulation of NLRP3 Inflammasome
- (2021) Sonia Marinho et al. Biomolecules
- A metabolomic analysis of thiol response for standard and modified N ‐acetyl cysteine treatment regimens in patients with acetaminophen overdose
- (2021) James W Dear et al. CTS-Clinical and Translational Science
- Rosmarinic acid ameliorates septic-associated mortality and lung injury in mice via GRP78/IRE1α/JNK pathway
- (2021) Zheng-kun Zhang et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Pirfenidone attenuates acetaminophen-induced liver injury via suppressing c-Jun N-terminal kinase phosphorylation
- (2021) Shigeki Tashiro et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The effects of rosmarinic acid on oxidative stress parameters and inflammatory cytokines in lipopolysaccharide-induced peripheral blood mononuclear cells
- (2020) Asie Sadeghi et al. MOLECULAR BIOLOGY REPORTS
- Lemon Balm and Its Constituent, Rosmarinic Acid, Alleviate Liver Damage in an Animal Model of Nonalcoholic Steatohepatitis
- (2020) Myungsuk Kim et al. Nutrients
- Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation
- (2020) Dong Hun Lee et al. Redox Biology
- Synovial Cell Migration is Associated with B Cell Activating Factor Expression Increased by TNF-α or Decreased by KR33426
- (2020) Jiyoung Lee et al. Biomolecules & Therapeutics
- The role of Neu1 in the protective effect of dipsacoside B on acetaminophen-induced liver injury
- (2020) Shuang Chen et al. Annals of Translational Medicine
- The cross-talk of NLRP3 inflammasome activation and necroptotic hepatocyte death in acetaminophen-induced mice acute liver injury
- (2020) L Li et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- KIF4A enhanced cell proliferation and migration via Hippo signaling and predicted a poor prognosis in esophageal squamous cell carcinoma
- (2020) Xiaozheng Sun et al. Thoracic Cancer
- Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice
- (2020) Nga T. Nguyen et al. TOXICOLOGY LETTERS
- What is the most appropriate dose of N-acetylcysteine after massive acetaminophen overdose?
- (2019) Robert G. Hendrickson CLINICAL TOXICOLOGY
- Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways
- (2019) Huahong Yang et al. Cell Communication and Signaling
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
- (2019) Humayun Sharif et al. NATURE
- Glioprotective Effect of Chitosan-Coated Rosmarinic Acid Nanoemulsions Against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Rat Astrocyte Primary Cultures
- (2019) Flávia Nathiely Silveira Fachel et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Hepatoprotective effect of artichoke leaf extracts in comparison with silymarin on acetaminophen-induced hepatotoxicity in mice
- (2019) Ghada Elsayed Elgarawany et al. JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY
- Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway
- (2019) Yang Feng et al. Oxidative Medicine and Cellular Longevity
- Beneficial effects of rosmarinic acid against alcohol-induced hepatotoxicity in rats
- (2018) Parisa Hasanein et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Evaluating the effect of diallyl sulfide on regulation of inflammatory mRNA expression in 3T3L1 adipocytes and RAW 264.7 macrophages during ethanol treatment
- (2018) Venkata Harini Kema et al. DRUG AND CHEMICAL TOXICOLOGY
- Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics
- (2018) Débora F. Gonçalves et al. LIFE SCIENCES
- Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions
- (2018) Mingzhu Yan et al. Redox Biology
- Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-κB and activating Nrf2/HO-1 signaling pathways
- (2018) Zheng Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Celastrol ameliorates acetaminophen-induced oxidative stress and cytotoxicity in HepG2 cells
- (2017) AT Jannuzzi et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway
- (2017) Jun Zeng et al. Journal of Neuroinflammation
- Protective effects of an ethanol extract ofAngelica keiskeiagainst acetaminophen-induced hepatotoxicity in HepG2 and HepaRG cells
- (2017) Yoon-Hee Choi et al. Nutrition Research and Practice
- Effects of rosmarinic acid on acetaminophen-induced hepatotoxicity in male Wistar rats
- (2017) Parisa Hasanein et al. PHARMACEUTICAL BIOLOGY
- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
- (2016) Eri H. Kobayashi et al. Nature Communications
- Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
- (2016) Kuo Du et al. Redox Biology
- The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes
- (2015) Yu Liu et al. Innate Immunity
- NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
- (2015) Hexin Shi et al. NATURE IMMUNOLOGY
- An Indole Derivative Protects Against Acetaminophen-Induced Liver Injury by Directly Binding to N-Acetyl-p-Benzoquinone Imine in Mice
- (2012) Ji-Hoon Park et al. ANTIOXIDANTS & REDOX SIGNALING
- Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury
- (2011) C. David Williams et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started