Synergistic protective effects of folic acid and resveratrol against fine particulate matter-induced heart malformations in zebrafish embryos

Using Immunofluorescence to Detect PM2.5-induced DNA Damage in Zebrafish Embryo Hearts

(2021) Yujie Huang et al.   Jove-Journal of Visualized Experiments

Developmental toxicity induced by particulate matter (PM2.5) in zebrafish (Danio rerio) model

(2021) Bangeppagari Manjunatha et al.   AQUATIC TOXICOLOGY

Maternal exposure to ambient air pollution and congenital heart defects in China

(2021) Bo-Yi Yang et al.   ENVIRONMENT INTERNATIONAL

Association between maternal exposure to gaseous pollutants and atrial septal defect in China: A nationwide population-based study

(2021) Fangyuan Yan et al.   ENVIRONMENTAL RESEARCH

Maternal Periconceptional Folic Acid Supplementation and Risk for Fetal Congenital Heart Defects

(2021) Di Wang et al.   JOURNAL OF PEDIATRICS

A Systematic Review of the Potential Chemoprotective Effects of Resveratrol on Doxorubicin-Induced Cardiotoxicity: Focus on the Antioxidant, Antiapoptotic, and Anti-Inflammatory Activities

(2021) Li-Feng Hu et al.   Oxidative Medicine and Cellular Longevity

Molecular Genetics and Complex Inheritance of Congenital Heart Disease

(2021) Nicholas S. Diab et al.   Genes

AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol

(2021) Yujie Huang et al.   TOXICOLOGY

Maternal air pollution exposure and congenital heart defects in offspring: A systematic review and meta-analysis

(2020) Cheng-Yang Hu et al.   CHEMOSPHERE

Vitamin B12 and folic acid alleviate symptoms of nutritional deficiency by antagonizing aryl hydrocarbon receptor

(2020) Daniel J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol protects against PM2.5-induced heart defects in zebrafish embryos as an antioxidant rather than as an AHR antagonist

(2020) Fei Ren et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Roles of Reactive Oxygen Species in Cardiac Differentiation, Reprogramming, and Regenerative Therapies

(2020) Jialiang Liang et al.   Oxidative Medicine and Cellular Longevity

Associations between weekly air pollution exposure and congenital heart disease

(2020) Qi Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Mechanisms of Developmental Toxicity of Dioxins and Related Compounds

(2019) Wataru Yoshioka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protection role of resveratrol against alcohol-induced heart defect in zebrafish embryos

(2019) Feng Wang et al.   CHINESE MEDICAL JOURNAL

AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos

(2019) Fei Ren et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Functional genomics and gene-environment interaction highlight the complexity of congenital heart disease caused by Notch pathway variants

(2019) Gavin Chapman et al.   HUMAN MOLECULAR GENETICS

Effect of particulate matter 2.5 on gene expression profile and cell signaling in JEG-3 human placenta cells

(2018) Woong Kim et al.   ENVIRONMENTAL TOXICOLOGY

Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring

(2018) Jing Zhu et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Prevalence of Congenital Heart Disease at Live Birth in China

(2018) Qu-Ming Zhao et al.   JOURNAL OF PEDIATRICS

Identification of clinically actionable variants from genome sequencing of families with congenital heart disease

(2018) Dimuthu Alankarage et al.   GENETICS IN MEDICINE

Prenatal exposure to PM2.5 and Congenital Heart Diseases in Taiwan

(2018) Ching-chun Huang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells

(2018) Hualing Fu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Aryl hydrocarbon receptor mediates the cardiac developmental toxicity of EOM from PM2.5 in P19 embryonic carcinoma cells

(2018) Tao Chen et al.   CHEMOSPHERE

PM 2.5 exposure in utero contributes to neonatal cardiac dysfunction in mice

(2017) Vineeta Tanwar et al.   ENVIRONMENTAL POLLUTION

Protective effects of folic acid on PM2.5-induced cardiac developmental toxicity in zebrafish embryos by targeting AhR and Wnt/β-catenin signal pathways

(2017) Cong Yue et al.   ENVIRONMENTAL TOXICOLOGY

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria-mediated apoptosis in zebrafish embryos

(2016) Xuesong Zhao et al.   AQUATIC TOXICOLOGY

Crosstalk between AhR and wnt/β-catenin signal pathways in the cardiac developmental toxicity of PM2.5 in zebrafish embryos

(2016) Hang Zhang et al.   TOXICOLOGY

Systematic synergy modeling: understanding drug synergy from a systems biology perspective

(2015) Di Chen et al.   BMC Systems Biology

When should we prescribe high-dose folic acid to prevent congenital heart defects?

(2015) James C. Huhta et al.   CURRENT OPINION IN CARDIOLOGY

Abnormalities in Alternative Splicing of Apoptotic Genes and Cardiovascular Diseases

(2015) Zodwa Dlamini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increasing impact of urban fine particles (PM2.5) on areas surrounding Chinese cities

(2015) Lijian Han et al.   Scientific Reports

Intersection of AHR and Wnt Signaling in Development, Health, and Disease

(2014) Andrew Schneider et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Trichloroethylene-Induced Gene Expression and DNA Methylation Changes in B6C3F1 Mouse Liver

(2014) Yan Jiang et al.   PLoS One

Cardiac Myocyte-Specific AHR Activation Phenocopies TCDD-Induced Toxicity in Zebrafish

(2014) Kevin A. Lanham et al.   TOXICOLOGICAL SCIENCES

Acute ZnO nanoparticles exposure induces developmental toxicity, oxidative stress and DNA damage in embryo-larval zebrafish

(2013) Xuesong Zhao et al.   AQUATIC TOXICOLOGY

Association between maternal folate concentrations during pregnancy and insulin resistance in Indian children

(2013) Ghattu V. Krishnaveni et al.   DIABETOLOGIA

Toxic assessment of urban atmospheric particle-bound PAHs: Relevance of composition and particle size in Barcelona (Spain)

(2013) Sofia Raquel Mesquita et al.   ENVIRONMENTAL POLLUTION

8-Oxoguanine DNA glycosylase 1 (ogg1) maintains the function of cardiac progenitor cells during heart formation in zebrafish

(2013) Lifeng Yan et al.   EXPERIMENTAL CELL RESEARCH

Moderately high intake of folic acid has a negative impact on mouse embryonic development

(2012) Leonie G. Mikael et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Zebrafish models in cardiac development and congenital heart birth defects

(2012) Shu Tu et al.   DIFFERENTIATION

A simple and reliable in vivo EROD activity measurement in single Fundulus heteroclitus embryo and larva

(2012) Floranne Le Bihanic et al.   MARINE ENVIRONMENTAL RESEARCH

Is red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection

(2011) Kim T. Lamont et al.   JOURNAL OF PINEAL RESEARCH

DNA damage and effects on glutathione-S-transferase activity induced by atrazine exposure in zebrafish (Danio rerio)

(2010) Lusheng Zhu et al.   ENVIRONMENTAL TOXICOLOGY

AhR agonist and genotoxicant bioavailability in a PAH-contaminated soil undergoing biological treatment

(2009) Erika Andersson et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake

(2009) S. W. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of oral folic acid upon plasma homocysteine, endothelial function and oxidative stress in patients with type 1 diabetes and microalbuminuria

(2008) F. Wotherspoon et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE