Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian Cancer

Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer

(2021) Milena Hornburg et al.   CANCER CELL

High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification

(2021) Siel Olbrecht et al.   Genome Medicine

Classification of High-Grade Serous Ovarian Carcinoma by Epithelial-to-Mesenchymal Transition Signature and Homologous Recombination Repair Genes

(2021) Min-Hwan Sohn et al.   Genes

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

(2020) Si Wang et al.   CELL

Single-cell transcriptional diversity is a hallmark of developmental potential

(2020) Gunsagar S. Gulati et al.   SCIENCE

Human T cells interacting with HNSCC‐derived mesenchymal stromal cells acquire Tissue‐Resident memory like properties

(2020) Alessio Mazzoni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21

(2020) Ali Hussain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TIGIT enhances CD4 + regulatory T‐cell response and mediates immune suppression in a murine ovarian cancer model

(2020) Fengzhen Chen et al.   Cancer Medicine

Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models

(2020) Nina Maenhoudt et al.   Stem Cell Reports

A single-cell landscape of high-grade serous ovarian cancer

(2020) Benjamin Izar et al.   NATURE MEDICINE

TIGIT Can Exert Immunosuppressive Effects on CD8+ T Cells by the CD155/TIGIT Signaling Pathway for Hepatocellular Carcinoma In Vitro

(2020) Changkun Zhang et al.   JOURNAL OF IMMUNOTHERAPY

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

(2020) Yilong Zou et al.   NATURE

EMT, cancer stem cells and autophagy; The three main axes of metastasis

(2020) Ghader Babaei et al.   BIOMEDICINE & PHARMACOTHERAPY

Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer

(2019) Mary L. Disis et al.   JAMA Oncology

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

(2019) Mark A. Eckert et al.   NATURE

The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance

(2019) Nele Loret et al.   Cancers

Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma

(2019) Lei Wu et al.   Cancer Immunology Research

OUP accepted manuscript

(2018)   BIOINFORMATICS

Ovarian cancer statistics, 2018

(2018) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Wnt7a activates canonical Wnt signaling, promotes bladder cancer cell invasion, and is suppressed by miR-370-3p

(2018) Xiaojing Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prevalence of PDL1 Amplification and Preliminary Response to Immune Checkpoint Blockade in Solid Tumors

(2018) Aaron M. Goodman et al.   JAMA Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Molecular Signatures of the Insulin-like Growth Factor 1-mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers

(2018) Armando Cevenini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies

(2018) Mathew Suji Eapen et al.   LABORATORY INVESTIGATION

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

(2018) Anushka Dongre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

(2018) Lauren E. Holz et al.   Cell Reports

Single-cell sequencing in ovarian cancer

(2018) Boris Winterhoff et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Iron addiction: a novel therapeutic target in ovarian cancer

(2017) D Basuli et al.   ONCOGENE

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

Safety and Antitumor Activity of Anti–PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer

(2015) Junzo Hamanishi et al.   JOURNAL OF CLINICAL ONCOLOGY

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function

(2014) Robert J. Johnston et al.   CANCER CELL

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Ten-Year Relative Survival for Epithelial Ovarian Cancer

(2012) Lauren A. Baldwin et al.   OBSTETRICS AND GYNECOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Epithelial–mesenchymal transition in ovarian cancer

(2009) Daniele Vergara et al.   CANCER LETTERS

Survival-Related Profile, Pathways, and Transcription Factors in Ovarian Cancer

(2009) Anne P. G Crijns et al.   PLOS MEDICINE

A Gene Signature Predicting for Survival in Suboptimally Debulked Patients with Ovarian Cancer

(2008) T. Bonome et al.   CANCER RESEARCH

Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

(2008) R. W. Tothill et al.   CLINICAL CANCER RESEARCH