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MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice

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Heterogeneity of hepatic stellate cells in a mouse model of non‐alcoholic steatohepatitis (NASH)

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Mechanisms of Fibrosis Development in NASH

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Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

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Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis

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Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis

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Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

(2019) Mashito Sakai et al.   IMMUNITY

Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

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NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances

(2018) Mazen Noureddin et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

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(2018) Scott L. Friedman et al.   NATURE MEDICINE

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(2018) Susanne Schuster et al.   Nature Reviews Gastroenterology & Hepatology

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

(2018) Charlotte L. Scott et al.   IMMUNITY

STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis

(2018) Yongsheng Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2018) Konstantin Kazankov et al.   Nature Reviews Gastroenterology & Hepatology

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(2017) Frank Tacke   JOURNAL OF HEPATOLOGY

CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors

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Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance

(2016) Pingping Li et al.   CELL

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

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Hepatocyte mitochondrial DNA released in microparticles and toll-like receptor 9 activation: A link between lipotoxicity and inflammation during nonalcoholic steatohepatitis

(2016) Maria Eugenia Inzaugarat et al.   HEPATOLOGY

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(2016) Laura Broutier et al.   Nature Protocols

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(2015) Margaret Alexander et al.   Nature Communications

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(2013) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

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CD206-Positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice

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(2010) Herbert Tilg et al.   HEPATOLOGY

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(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

The gut–liver-axis: Endotoxemia, inflammation, insulin resistance and NASH

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