Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors

Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen

(2021) Jordi Rodon et al.   Frontiers in Pharmacology

Development of Membrane-Active Honokiol/Magnolol Amphiphiles as Potent Antibacterial Agents against Methicillin-Resistant Staphylococcus aureus (MRSA)

(2021) Yong Guo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Honokiol: A review of its pharmacological potential and therapeutic insights

(2021) Abdur Rauf et al.   PHYTOMEDICINE

Synthesis and Biological Evaluation of Honokiol Derivatives Bearing 3-((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)oxazol-2(3H)-ones as Potential Viral Entry Inhibitors against SARS-CoV-2

(2021) Yong Guo et al.   Pharmaceuticals

Inhibitory effect of honokiol on furin-like activity and SARS-CoV-2 infection

(2021) Takashi Tanikawa et al.   Journal of Traditional and Complementary Medicine

Novel 1,3,4-thiadiazole/oxadiazole-linked honokiol derivatives suppress cancer via inducing PI3K/Akt/mTOR-dependent autophagy

(2021) Ting Xu et al.   BIOORGANIC CHEMISTRY

Development of Novel (+)-Nootkatone Thioethers Containing 1,3,4-Oxadiazole/Thiadiazole Moieties as Insecticide Candidates against Three Species of Insect Pests

(2021) Ruige Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Improving the antioxidant activity of natural antioxidant honokiol by introducing the amino group

(2021) Xiaohu Liu et al.   JOURNAL OF MOLECULAR MODELING

Protective Role of Combined Polyphenols and Micronutrients against Influenza A Virus and SARS-CoV-2 Infection In Vitro

(2021) Marta De Angelis et al.   Biomedicines

Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine

(2020) Xiaojia Shi et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors

(2020) Manvendra Singh et al.   Cell Reports

Inhibition of Herpes Simplex Virus-1 Replication by Natural Compound Honokiol

(2019) Shuai Liu et al.   VIROLOGICA SINICA

Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

(2019) Gao-Jie Ye et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of new norfloxacin-1,3,4-oxadiazole hybrids as antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA)

(2019) Yong Guo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Honokiol: A Review of Its Anticancer Potential and Mechanisms

(2019) Chon Phin Ong et al.   Cancers

Design, synthesis and antibacterial evaluation of honokiol derivatives

(2018) Bo Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, semisynthesis, α -glucosidase inhibitory, cytotoxic, and antibacterial activities of p -terphenyl derivatives

(2018) Xue-Qing Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Natural Products as a Source for New Leads in Cancer Research and Treatment

(2018) Célia Cabral et al.   Evidence-based Complementary and Alternative Medicine

Why Are the Majority of Active Compounds in the CNS Domain Natural Products? A Critical Analysis

(2018) Sonali S. Bharate et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potent anti-inflammatory effects of honokiol in human fetal membranes and myometrium

(2018) Yasaswi Kaumadha Wijesuriya et al.   PHYTOMEDICINE

Anti-ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery

(2016) Chun-Yan Shen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

The re-emergence of natural products for drug discovery in the genomics era

(2015) Alan L. Harvey et al.   NATURE REVIEWS DRUG DISCOVERY

2-Aminobenzoxazole ligands of the hepatitis C virus internal ribosome entry site

(2014) Kevin D. Rynearson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structural Modification of Honokiol, a Biphenyl Occurring in Magnolia officinalis: the Evaluation of Honokiol Analogues as Inhibitors of Angiogenesis and for Their Cytotoxicity and Structure–Activity Relationship

(2011) Liang Ma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Magnolia dealbata Zucc and its active principles honokiol and magnolol stimulate glucose uptake in murine and human adipocytes using the insulin-signaling pathway

(2011) Angel Josabad Alonso-Castro et al.   PHYTOMEDICINE

Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors

(2010) R. J. Leeman-Neill et al.   CLINICAL CANCER RESEARCH

Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells

(2009) Eun-Jung Park et al.   CANCER LETTERS

Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity

(2009) Jia Hu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE