Antitumor Activity of Chitosan-Coated Iron Oxide Nanocomposite Against Hepatocellular Carcinoma in Animal Models

RF hyperthermia by encapsulated Fe3O4 nanoparticles induces cancer cell death via time-dependent caspase-3 activation

(2020) Anjali Chauhan et al.   Nanomedicine

Fe3O4 Nanoparticles Attenuated Salmonella Infection in Chicken Liver Through Reactive Oxygen and Autophagy via PI3K/Akt/mTOR Signaling

(2020) Yiru Shen et al.   Frontiers in Physiology

Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology

(2020) Shuya Kasai et al.   Biomolecules

Nanoparticles induce autophagy via mTOR pathway inhibition and reactive oxygen species generation

(2020) Lu Jia et al.   Nanomedicine

Targeting the mTOR Signaling Pathway Utilizing Nanoparticles: A Critical Overview

(2019) Mariia Lunova et al.   Cancers

Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains

(2019) Lin Li et al.   Nanotoxicology

Synthesis and characterization of chitosan/iron oxide nanocomposite for biomedical applications

(2019) Devaraj Bharathi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Nanoparticle Conjugation of Ginsenoside Rg3 Inhibits Hepatocellular Carcinoma Development and Metastasis

(2019) Zhigang Ren et al.   Small

Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma

(2019) Nancy S. Younis et al.   Scientific Reports

Oral exposure to silver nanoparticles increases oxidative stress markers in the liver of male rats and deregulates the insulin signalling pathway and p53 and cleaved caspase 3 protein expression

(2018) Jordi Blanco et al.   FOOD AND CHEMICAL TOXICOLOGY

Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity

(2018) Kanchanlata Singh et al.   SAUDI PHARMACEUTICAL JOURNAL

Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood

(2018) Susann Wolf-Grosse et al.   Nanomedicine

Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment

(2018) Marco Cordani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antihepatocarcinoma Effect of Portulaca oleracea L. in Mice by PI3K/Akt/mTOR and Nrf2/HO-1/NF-κB Pathway

(2017) Zheng Guoyin et al.   Evidence-based Complementary and Alternative Medicine

Structural basis for alpha fetoprotein-mediated inhibition of caspase-3 activity in hepatocellular carcinoma cells

(2017) Bo Lin et al.   INTERNATIONAL JOURNAL OF CANCER

Nano-Chitosan Particles in Anticancer Drug Delivery: An Up-to-Date Review

(2017) Pooja R. Kamath et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Nano-sized zinc oxide and silver, but not titanium dioxide, induce innate and adaptive immunity and antiviral response in differentiated THP-1 cells

(2017) Wing-Lam Poon et al.   Nanotoxicology

Cuprous oxide nanoparticles inhibit the growth of cervical carcinoma by inducing autophagy

(2017) Leilei Xia et al.   Oncotarget

Mucoadhesive Chitosan-Pectinate Nanoparticles for the Delivery of Curcumin to the Colon

(2016) Enas Alkhader et al.   AAPS PHARMSCITECH

Nanoparticles and direct immunosuppression

(2016) Terrika A Ngobili et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Iron oxide nanoparticles modulate lipopolysaccharide-induced inflammatory responses in primary human monocytes

(2016) Susan Grosse et al.   International Journal of Nanomedicine

Protective effect of platycodin D on liver injury in alloxan-induced diabetic mice via regulation of Treg/Th17 balance

(2015) Tong Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation

(2015) Neena G. Shetake et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

(2015) Hui-Wen Chiu et al.   Nanoscale

Layer-by-layer assembly of liposomal nanoparticles with PEGylated polyelectrolytes enhances systemic delivery of multiple anticancer drugs

(2014) Thiruganesh Ramasamy et al.   Acta Biomaterialia

PI3K/AKT signaling pathway and cancer: an updated review

(2014) Miriam Martini et al.   ANNALS OF MEDICINE

Toll-like receptor 6 mediated inflammatory and functional responses of zinc oxide nanoparticles primed macrophages

(2014) Ruchi Roy et al.   IMMUNOLOGY

ERK pathway is activated in bare-FeNPs-induced autophagy

(2013) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: Implications for the treatment of human liver cancer

(2013) Chunmei Wang et al.   CELL CYCLE

Radiologic-histological correlation of hepatocellular carcinoma treated via pre-liver transplant locoregional therapies

(2013) Galal El-Gazzaz et al.   Hepatobiliary & Pancreatic Diseases International

Chitosan-Based Polyelectrolyte Complexes as Potential Nanoparticulate Carriers: Physicochemical and Biological Characterization

(2013) Thiruganesh Ramasamy et al.   PHARMACEUTICAL RESEARCH

Emerging Targeted Strategies in Advanced Hepatocellular Carcinoma

(2013) Richard Finn   SEMINARS IN LIVER DISEASE

In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa

(2013) Moustafa Fathy et al.   Environmental Health and Preventive Medicine

Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications

(2012) L. Harivardhan Reddy et al.   CHEMICAL REVIEWS

Synthesis optimization and characterization of chitosan-coated iron oxide nanoparticles produced for biomedical applications

(2012) Gozde Unsoy et al.   JOURNAL OF NANOPARTICLE RESEARCH

POSSIBLE INVOLVEMENT OF OXIDATIVE STRESS IN DIETHYLNITROSAMINE-INDUCED HEPATOCARCINOGENESIS: CHEMOPREVENTIVE EFFECT OF CURCUMIN

(2011) HEBATALLAH A. DARWISH et al.   JOURNAL OF FOOD BIOCHEMISTRY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

mTOR, Cancer and Transplantation

(2008) Edward K. Geissler et al.   AMERICAN JOURNAL OF TRANSPLANTATION