Accelerated epigenetic aging in newborns with Down syndrome

Immune Dysregulation in Children With Down Syndrome

(2020) Dean Huggard et al.   Frontiers in Pediatrics

Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in etiology

(2019) Amalie B. Nielsen et al.   HAEMATOLOGICA

Inherited genetic susceptibility of acute lymphoblastic leukemia in Down syndrome

(2019) Austin L. Brown et al.   BLOOD

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

(2019) Maurice Labuhn et al.   CANCER CELL

Critical evaluation of copy number variant calling methods using DNA methylation

(2019) Varun Kilaru et al.   GENETIC EPIDEMIOLOGY

Clinical implications of immune‐mediated diseases in children with Down syndrome

(2019) Ruud H. J. Verstegen et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

National population‐based estimates for major birth defects, 2010–2014

(2019) Cara T. Mai et al.   Birth Defects Research

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

(2018) Steve Horvath et al.   Aging-US

The role of fetal growth restriction in the association between Down syndrome and perinatal mortality

(2018) Ruofan Yao et al.   Journal of Maternal-Fetal & Neonatal Medicine

DNA methylation of cord blood cell types: Applications for mixed cell birth studies

(2016) Kelly M. Bakulski et al.   Epigenetics

Accelerated epigenetic aging in Down syndrome

(2015) Steve Horvath et al.   AGING CELL

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Domains of genome-wide gene expression dysregulation in Down’s syndrome

(2014) Audrey Letourneau et al.   NATURE

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

(2014) Andrew A Lane et al.   NATURE GENETICS

Atypical aging in down syndrome

(2013) Warren B. Zigman   Developmental Disabilities Research Reviews

DNA methylome profiling using neonatal dried blood spot samples: A proof-of-principle study

(2013) Mads Vilhelm Hollegaard et al.   MOLECULAR GENETICS AND METABOLISM

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

(2012) A. Roy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA