Virus-Like Particle-Templated Silica-Adjuvanted Nanovaccines with Enhanced Humoral and Cellular Immunity

Mechanistic understanding of the aspect ratio-dependent adjuvanticity of engineered aluminum oxyhydroxide nanorods in prophylactic vaccines

(2022) Zhihui Liang et al.   Nano Today

Polymer Coatings on Virus-like Particle Nanoreactors at Low Ionic Strength—Charge Reversal and Substrate Access

(2021) Pawel Kraj et al.   BIOMACROMOLECULES

An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery

(2021) Kailash C. Petkar et al.   Pharmaceutics

Chimeric VLPs Based on HIV-1 Gag and a Fusion Rabies Glycoprotein Induce Specific Antibodies against Rabies and Foot-and-Mouth Disease Virus

(2021) Diego Fontana et al.   Vaccines

Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants

(2021) Zhihui Liang et al.   BIOMATERIALS

Engineered Hydroxyapatite Nanoadjuvants with Controlled Shape and Aspect Ratios Reveal Their Immunomodulatory Potentials

(2021) Lei Zhang et al.   ACS Applied Materials & Interfaces

The Ebola virus glycoprotein and its immune responses across multiple vaccine platforms

(2020) Kyle O’Donnell et al.   Expert Review of Vaccines

Cytosolic delivery of HBsAg and enhanced cellular immunity by pH-responsive liposome

(2020) Fumin Hu et al.   JOURNAL OF CONTROLLED RELEASE

An Apoferritin–Hemagglutinin Conjugate Vaccine with Encapsulated Nucleoprotein Antigen Peptide from Influenza Virus Confers Enhanced Cross Protection

(2020) Jiangxue Wei et al.   BIOCONJUGATE CHEMISTRY

The Roles of CD8+ T Cell Subsets in Antitumor Immunity

(2020) Michael St. Paul et al.   TRENDS IN CELL BIOLOGY

A biomimetic VLP influenza vaccine with interior NP/exterior M2e antigens constructed through a temperature shift-based encapsulation strategy

(2020) Jiangxue Wei et al.   VACCINE

The pore size of mesoporous silica nanoparticles regulates their antigen delivery efficiency

(2020) Xiaoyu Hong et al.   Science Advances

Particulate Alum via Pickering Emulsion for an Enhanced COVID‐19 Vaccine Adjuvant

(2020) Sha Peng et al.   ADVANCED MATERIALS

Dendritic Mesoporous Silica Nanoparticle Adjuvants Modified with Binuclear Aluminum Complex: Coordination Chemistry Dictates Adjuvanticity

(2020) Yang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

(2020) Carolyn Rydyznski Moderbacher et al.   CELL

Measuring of IgG2c isotype instead of IgG2a in immunized C57BL/6 mice with Plasmodium vivax TRAP as a subunit vaccine candidate in order to correct interpretation of Th1 versus Th2 immune response

(2020) Saeed Nazeri et al.   EXPERIMENTAL PARASITOLOGY

First human efficacy study of a plant-derived influenza vaccine

(2020) John S Tregoning   LANCET

Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity

(2019) Shuting Shi et al.   VACCINE

Surface Modification of Stöber Silica Nanoparticles with Controlled Moiety Densities Determines Their Cytotoxicity Profiles in Macrophages

(2019) Min Li et al.   LANGMUIR

The influence of inter-particle forces on diffusion at the nanoscale

(2019) Francesco Giorgi et al.   Scientific Reports

Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes

(2018) Vahid Mirshafiee et al.   ACS Nano

Biomineralization State of Viruses and Their Biological Potential

(2018) Xiaoyu Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

pH-Dependent silica nanoparticle dissolution and cargo release

(2018) Giorgia Giovaninni et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Exploration of Antigen Induced CaCO3 Nanoparticles for Therapeutic Vaccine

(2018) Shuang Wang et al.   Small

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

(2018) Jorge C. G. Blanco et al.   Nature Communications

Controllable synthesis of raspberry-like PS–SiO2 nanocomposite particles via Pickering emulsion polymerization

(2018) Xiaotian Zhang et al.   RSC Advances

New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue

(2018) Karl D. Brune et al.   Frontiers in Immunology

Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want

(2018) Harm HogenEsch et al.   npj Vaccines

Asymmetric Silica Nanoparticles with Tunable Head–Tail Structures Enhance Hemocompatibility and Maturation of Immune Cells

(2017) Prasanna Lakshmi Abbaraju et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

(2017) Jianqin Lu et al.   Nature Communications

Understanding the Effect of Surface Chemistry of Mesoporous Silica Nanorods on Their Vaccine Adjuvant Potency

(2017) Yannan Yang et al.   Advanced Healthcare Materials

Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer

(2016) Xiangsheng Liu et al.   ACS Nano

Mechanisms of Antigen Adsorption Onto an Aluminum-Hydroxide Adjuvant Evaluated by High-Throughput Screening

(2016) Vanessa Jully et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Generation and immunogenicity of porcine circovirus type 2 chimeric virus-like particles displaying porcine reproductive and respiratory syndrome virus GP5 epitope B

(2016) Gaowei Hu et al.   VACCINE

Robust vaccine formulation produced by assembling a hybrid coating of polyethyleneimine–silica

(2016) Guangchuan Wang et al.   Chemical Science

Nanomaterial-based vaccine adjuvants

(2016) Bingbing Sun et al.   Journal of Materials Chemistry B

Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping

(2015) Bingbing Sun et al.   ACS Nano

P22 virus-like particles constructed Au/CdS plasmonic photocatalytic nanostructures for enhanced photoactivity

(2015) Ziyou Zhou et al.   CHEMICAL COMMUNICATIONS

CPMV-induced synthesis of hollow mesoporous SiO2 nanocapsules with excellent performance in drug delivery

(2015) Koushi Kumar et al.   DALTON TRANSACTIONS

Obtaining information about protein secondary structures in aqueous solution using Fourier transform IR spectroscopy

(2015) Huayan Yang et al.   Nature Protocols

NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes

(2015) Bingbing Sun et al.   Small

Factors affecting alum–protein interactions

(2014) Min Huang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Engineering an Effective Immune Adjuvant by Designed Control of Shape and Crystallinity of Aluminum Oxyhydroxide Nanoparticles

(2013) Bingbing Sun et al.   ACS Nano

A model of lysosomal pH regulation

(2013) Yoichi Ishida et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

(2013) Karishma T. Mody et al.   Nanoscale

Novel Vaccine Delivery System Induces Robust Humoral and Cellular Immune Responses Based on Multiple Mechanisms

(2013) Yue-Qi Wang et al.   Advanced Healthcare Materials

Regulation of Adaptive Immunity; The Role of Interleukin-10

(2013) T. H. Sky Ng et al.   Frontiers in Immunology

CD4+T Cells: Differentiation and Functions

(2012) Rishi Vishal Luckheeram et al.   Clinical & Developmental Immunology

Structural and Immunological Analysis of Anthrax Recombinant Protective Antigen Adsorbed to Aluminum Hydroxide Adjuvant

(2012) Leslie Wagner et al.   Clinical and Vaccine Immunology

Immunization of mice by Hollow Mesoporous Silica Nanoparticles as carriers of Porcine Circovirus Type 2 ORF2 Protein

(2012) Hui-Chen Guo et al.   Virology Journal

Oxide formation on biological nanostructures via a structure-directing agent: towards an understanding of precise structural transcription

(2012) Fuke Wang et al.   Chemical Science

Norovirus Vaccine against Experimental Human Norwalk Virus Illness

(2011) Robert L. Atmar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quantifying colocalization by correlation: The Pearson correlation coefficient is superior to the Mander's overlap coefficient

(2010) Jeremy Adler et al.   CYTOMETRY PART A

The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza

(2010) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Immunological parameters related to the adjuvant effect of the ordered mesoporous silica SBA-15

(2010) Luciana V. Carvalho et al.   VACCINE

Development of a Direct Alhydrogel Formulation Immunoassay (DAFIA)

(2009) Daming Zhu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Intracellular Localization and Cytotoxicity of Spherical Mesoporous Silica Nano- and Microparticles

(2009) Qianjun He et al.   Small

Relationship between CD107a expression and cytotoxic activity

(2008) Esin Aktas et al.   CELLULAR IMMUNOLOGY

Alum adjuvanticity: Unraveling a century old mystery

(2008) Ennio De Gregorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune response

(2008) Bethany Hansen et al.   VACCINE