Article
Nutrition & Dietetics
Marie Mathieu, Pascale Guillot, Typhaine Riaudel, Anne-Sophie Boureau, Guillaume Chapelet, Celine Brouessard, Laure de Decker, Gilles Berrut
Summary: This study aimed to explore the relationship between osteoporosis and sarcopenia in women aged 75 or older, revealing a significant association between fat mass and bone density, with osteosarcopenic patients having lower fat mass and body mass index.
Article
Endocrinology & Metabolism
Jingzheng Fan, Yuyan Jiang, Junlian Qiang, Bin Han, Qiang Zhang
Summary: This study investigated the relationship between body fat accumulation, fat distribution, and bone mineral density in non-obese postmenopausal women. The results showed a positive association between total fat mass and bone mineral density, while fat distribution had a negative correlation with bone mineral density.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Nipith Charoenngam, Caroline M. Apovian, Chatlert Pongchaiyakul
Summary: This study aims to determine the association of lean mass and fat mass with bone mineral density in Thais. The results show that in men, lean mass index is positively correlated with lumbar spine and femoral neck bone density, while fat mass index is negatively correlated with femoral neck bone density. In women, both lean mass and fat mass index are positively correlated with lumbar spine and femoral neck bone density. These findings indicate a sex-specific influence of fat mass on bone density in Thais.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Pilar Sanchis, Rafael Maria Prieto, Jadwiga Konieczna, Felix Grases, Itziar Abete, Jordi Salas-Salvado, Vicente Martin, Miguel Ruiz-Canela, Nancy Babio, Jesus Francisco Garcia-Gavilan, Albert Goday, Antonia Costa-Bauza, Jose Alfredo Martinez, Dora Romaguera
Summary: The main objective of this study was to examine the relationship between dietary phytate intake and bone mineral density (BMD) in a Mediterranean population of postmenopausal women. The results showed that phytate intake was positively associated with BMD in Mediterranean postmenopausal women, indicating a potential protective effect on bone. However, further large-scale, long-term, and randomized prospective clinical studies are needed to assess the potential benefits of phytate consumption on BMD in postmenopausal women.
Article
Sport Sciences
Annie M. Skinner, Dimitris Vlachopoulos, Alan R. Barker, Sarah A. Moore, Alex Rowlands, Sonja Soininen, Eero A. Haapala, Juuso Vaisto, Kate Westgate, Soren Brage, Timo A. Lakka
Summary: The study aimed to assess the associations of physical activity (PA) volume, PA intensity distribution, and moderate-to-vigorous PA (MVPA) with bone mineral content, lean mass, and fat mass in children. The results showed that PA volume was positively associated with bone mineral content in both females and males, and positively associated with lean mass (males) or negatively associated with fat mass (males). PA intensity was negatively associated with bone mineral content in males. MVPA was positively associated with lean mass and negatively associated with fat mass in both females and males.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Orthopedics
Zhuo-Jie Liu, Cheng Zhang, Chi Ma, Huan Qi, Ze-Hong Yang, Hao-Yu Wu, Ke-Di Yang, Jun-Yu Lin, Tak-Man Wong, Zhao-Yang Li, Chun-Hai Li, Yue Ding
Summary: The newly-developed automatic PLQCT system showed higher precision in measuring bone mineral density and diagnosing osteoporosis compared to traditional QCT systems. The system demonstrated good reproducibility and accuracy in diagnosing osteoporosis, with potential for broad clinical application and translational research.
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2022)
Article
Endocrinology & Metabolism
Aaron Misakian, Michelle McLoughlin, Louisa C. Pyle, Thomas F. Kolon, Andrea Kelly, Maria G. Vogiatzi
Summary: This study investigated bone mineral density and body composition in adolescents with CAIS, showing a bone mass deficit in this population. Further research is needed to understand the extent of BMD abnormalities, the impact of early gonadectomy, and the optimal hormone replacement therapy regimen for bone accrual. Data on lean mass were reassuring.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
William D. Leslie, Heenam Goel, Neil Binkley, Eugene McCloskey, Didier Hans
Summary: Lumbar spine trabecular bone score (TBS) is a bone mineral density (BMD)-independent risk factor for fracture, but its sensitivity to technical factors and oral antiresorptive therapies is limited. This study analyzed TBS changes over time and in response to osteoporosis treatment, and found that TBS is strongly affected by technical factors and has little effect on monitoring response to antiresorptive treatment. Therefore, the current version of the TBS algorithm has limited usefulness in untreated individuals or routine clinical practice.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Immunology
Cheng Peng, Feng Liu, Kuan-Jui Su, Xu Lin, Yu-Qian Song, Jie Shen, Shi-Di Hu, Qiao-Cong Chen, Hui-Hui Yuan, Wen-Xi Li, Chun-Ping Zeng, Hong-Wen Deng, Hui-Ling Lou
Summary: Strong relationships were found between appendicular lean mass (ALM) and bone mineral density (BMD). Leveraging pleiotropy with BMD, this study identified 26 novel potential pleiotropic SNPs for ALM. Through a combined analysis of two large independent genome wide association studies, this research demonstrated the efficiency and reliability of the cFDR methodology in detecting trait-associated genetic variants for ALM.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Endocrinology & Metabolism
Heidi J. Kalkwarf, John A. Shepherd, Bo Fan, Rashmi D. Sahay, Richard F. Ittenbach, Andrea Kelly, Kimberly Yolton, Babette S. Zemel
Summary: This study aimed to identify the effects of age, sex, and population ancestry on BMC and aBMD in young children, and to provide reference ranges and stature adjustments for bone health assessments.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Katherine N. Haseltine, Tariq Chukir, Pinar J. Smith, Justin T. Jacob, John P. Bilezikian, Azeez Farooki
Summary: Bone mineral density measurement and FRAX assessment tools can help evaluate fracture risk and guide decisions for osteoporosis pharmacologic treatment. Specific populations like postmenopausal women and men over 50 should receive pharmacologic treatment according to guidelines. Monitoring BMD regularly and considering secondary causes or non-compliance is important during treatment.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Nutrition & Dietetics
Ching-Ti Liu, David Karasik, Hanfei Xu, Yanhua Zhou, Kerry Broe, L. Adrienne Cupples, Lisette Cpgm de Groot, Annelies Ham, Marian T. Hannan, Yi-Hsiang Hsu, Paul Jacques, Robert R. McLean, Ligi Paul, Jacob Selhub, Katerina Trajanoska, Nathalie van der Velde, Natasja van Schoor, Douglas P. Kiel
Summary: Genetic variants in the 1-carbon methylation pathway have been shown to modify the association of B vitamin and biomarker concentrations with bone density and strength. These interactions provide insights into the mechanistic understanding of the role of the 1-carbon metabolism pathway on bone mineral density and fracture risks, warranting further replication and functional validation.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Endocrinology & Metabolism
Kathleen T. Nevola, Douglas P. Kiel, Andrew R. Zullo, Stefan Weiss, Georg Homuth, Ines Foessl, Barbara Obermayer-Pietsch, Katherine J. Motyl, Christine W. Lary
Summary: Osteoporosis is a common disease, and recent studies have found that individuals using beta blockers have higher bone density and lower fracture risk. Certain miRNAs have been associated with adrenergic signaling and bone density. This study investigates the potential role of miRNAs in the association between beta blocker use and bone density.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
Navira Samad, Hanh H. Nguyen, Hikaru Hashimura, Julie Pasco, Mark Kotowicz, Boyd J. Strauss, Peter R. Ebeling, Frances Milat, Amanda J. Vincent
Summary: Low bone density (BMD) and fractures are common in women with premature ovarian insufficiency (POI), but data on bone microarchitecture and body composition are lacking. This study aimed to assess and characterize the musculoskeletal phenotype in women with POI and evaluate the effects of estrogen replacement therapy (ERT). The results showed that women with POI had deficits in BMD, trabecular microarchitecture, and lean mass. However, regular ERT protected against declines in bone variables and increased lean mass. Therefore, assessing skeletal and muscle health and promoting adherence to ERT are crucial in optimizing musculoskeletal outcomes in POI.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Joseph C. Wong, Sheila O'Neill, Belinda R. Beck, Mark R. Forwood, Soo Keat Khoo
Summary: This study found that obesity classified using percentage body fat (PBF) was more severe than using body mass index (BMI) and fat mass index (FMI), possibly due to its lower predetermined threshold. Additionally, from the age of 50-59, the difference between PBF and BMI/FMI was greater, which may be attributed to age-related lean mass loss.
Article
Engineering, Manufacturing
Scott C. Ellis, Shashank Rao, Dheeraj Raju, Thomas J. Goldsby
PRODUCTION AND OPERATIONS MANAGEMENT
(2018)
Article
Medicine, Research & Experimental
Shima Dowla, May Pendergrass, Mark Bolding, Barbara Gower, Kevin Fontaine, Ambika Ashraf, Taraneh Soleymani, Shannon Morrison, Amy Goss
CONTEMPORARY CLINICAL TRIALS
(2018)
Article
Nursing
David E. Vance, Michael Jensen, Frida Tende, James L. Raper, Shannon Morrison, Pariya L. Fazeli
JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE
(2018)
Letter
Hematology
Huy P. Pham, Dheeraj Raju, Joseph Schwartz
JOURNAL OF CLINICAL APHERESIS
(2018)
Article
Critical Care Medicine
Monisha A. Kumar, Wenjing Cao, Huy P. Pham, Dheeraj Raju, Kelsey Nawalinski, Eileen Maloney-Wilensky, James Schuster, X. Long Zheng
JOURNAL OF NEUROTRAUMA
(2019)
Article
Nursing
Pauline A. Swiger, Lori A. Loan, Dheeraj Raju, Sara T. Breckenridge-Sproat, Rebecca S. Miltner, Patricia A. Patrician
RESEARCH IN NURSING & HEALTH
(2018)
Article
Nursing
Bryan Combs, Karen Heaton, Dheeraj Raju, D. E. Vance, W. Karl Sieber
WORKPLACE HEALTH & SAFETY
(2018)
Article
Hematology
Elizabeth M. Staley, Dheeraj Raju, Lance A. Williams, Chong H. Kim, Ning Jiang, Huy P. Pham
JOURNAL OF CLINICAL APHERESIS
(2018)
Article
Nursing
Allison Shorten, Brett Shorten, Angela Fagerlin, Jessica Illuzzi, Holly Powell Kennedy, Christian Pettker, Dheeraj Raju, Robin Whittemore
JOURNAL OF MIDWIFERY & WOMENS HEALTH
(2019)
Article
Medicine, General & Internal
Mary S. McCarthy, Evelyn B. Elshaw, Barbara M. Szekely, Dheeraj Raju
Article
Oncology
Jacqueline B. Vo, Kelly M. Kenzik, Wendy Landier, Dheeraj Raju, James K. Kirklin, Karen Meneses
Summary: Research on young breast cancer survivors is limited, highlighting the importance of assessing cardiovascular disease risk in this population. Anthracyclines and trastuzumab were not predictive of excess heart age, while factors such as endocrine therapy and transitioning to postmenopausal status were found to be associated with excess heart age. Further studies are needed to evaluate long-term heart age changes and develop a modified tool that incorporates treatment risk for early intervention in high-risk cancer patients.
CANCER CAUSES & CONTROL
(2021)
Article
Nursing
Susan P. McMullan, Dheeraj Raju, Patricia A. Patrician
Summary: This paper reports the final psychometric validation of the Certified Registered Nurse Anesthetist (CRNA) Workload Perception Scale (CWPS), with a revised 7-item CWPS developed based on the results of parametric and non-parametric analysis.
JOURNAL OF NURSING MEASUREMENT
(2022)
Article
Psychology, Multidisciplinary
Dheeraj Raju, Lisa Beck, Andres Azuero, Casey Azuero, David Vance, Rebecca Allen
JOURNAL OF HOMOSEXUALITY
(2019)
Article
Nursing
Holly B. Goldberg, Allison Shorten, Brett Shorten, Dheeraj Raju
JOURNAL OF NURSING MEASUREMENT
(2018)
Article
Obstetrics & Gynecology
Karen Meneses, Silvia Gisiger-Camata, Rachel Benz, Dheeraj Raju, Jennifer R. Bail, Tanya J. Benitez, Dorothy Pekmezi, Patrick McNees
Review
Endocrinology & Metabolism
Linsey U. Gani, Chanika Sritara, Robert D. Blank, Weiwen Chen, Julia Gilmour, Ruban Dhaliwal, Ranjodh Gill
Summary: Dual-energy X-ray absorptiometry (DXA) is the gold standard method for measuring bone mineral density (BMD), which is strongly associated with fracture risk. The International Society for Clinical Densitometry (ISCD) has released new official positions on follow-up DXA examinations, highlighting the importance of considering the clinical context and individualized testing intervals.
JOURNAL OF CLINICAL DENSITOMETRY
(2024)
Article
Endocrinology & Metabolism
Andia Cheneymann, Josephine Therkildsen, Simon Winther, Louise Nissen, Jesper Thygesen, Bente L. Langdahl, Ellen-Margrethe Hauge, Morten Bottcher
Summary: Osteoporosis is often overlooked, and contrast-enhanced CT scans used for other diseases may overestimate bone mineral density. Adjustments for this effect are necessary before contrast-enhanced images can be clinically utilized for BMD screening.
JOURNAL OF CLINICAL DENSITOMETRY
(2024)