Article
Nutrition & Dietetics
Marie Mathieu, Pascale Guillot, Typhaine Riaudel, Anne-Sophie Boureau, Guillaume Chapelet, Celine Brouessard, Laure de Decker, Gilles Berrut
Summary: This study aimed to explore the relationship between osteoporosis and sarcopenia in women aged 75 or older, revealing a significant association between fat mass and bone density, with osteosarcopenic patients having lower fat mass and body mass index.
Article
Endocrinology & Metabolism
Nipith Charoenngam, Caroline M. Apovian, Chatlert Pongchaiyakul
Summary: This study aims to determine the association of lean mass and fat mass with bone mineral density in Thais. The results show that in men, lean mass index is positively correlated with lumbar spine and femoral neck bone density, while fat mass index is negatively correlated with femoral neck bone density. In women, both lean mass and fat mass index are positively correlated with lumbar spine and femoral neck bone density. These findings indicate a sex-specific influence of fat mass on bone density in Thais.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Longti Li, Huiqin Zhong, Ya Shao, Xu Zhou, Yu Hua, Maoqian Chen
Summary: The study found a positive correlation between lean body mass and total BMD, while visceral fat mass showed a negative correlation. Additionally, the ratio of lean body mass to visceral fat mass was positively associated with BMD. Subgroup analysis demonstrated robustness across most groups except for the subgroup with diabetes.
ARCHIVES OF PUBLIC HEALTH
(2023)
Article
Endocrinology & Metabolism
Lijuan Yang, Huihui Deng, Wei Pan, Xiaoyan Huang, Ke Xu, Xingxing Zhang, Xiang Hu, Xuejiang Gu
Summary: The study found that higher levels of leg fat were associated with a lower risk of osteoporosis, independent of total lean mass.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2022)
Article
Endocrinology & Metabolism
Aaron Misakian, Michelle McLoughlin, Louisa C. Pyle, Thomas F. Kolon, Andrea Kelly, Maria G. Vogiatzi
Summary: This study investigated bone mineral density and body composition in adolescents with CAIS, showing a bone mass deficit in this population. Further research is needed to understand the extent of BMD abnormalities, the impact of early gonadectomy, and the optimal hormone replacement therapy regimen for bone accrual. Data on lean mass were reassuring.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Shuna Li, Li Li, Aozi Feng, Tao Huang, Chong Chen, Ningxia He, Liying Huang, Jun Lyu
Summary: This study found a positive association between hypertension and lumbar bone mineral density in both males older than 50 years and postmenopausal females. However, a similar pattern was not found in the femoral neck.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Nutrition & Dietetics
Patricia Paula da Fonseca Grili, Camila Vilarinho Vidigal, Geise Ferreira da Cruz, Ben-Hur Albergaria, Jose Luiz Marques-Rocha, Taisa Sabrina Silva Pereira, Valdete Regina Guandalini
Summary: This study aimed to identify nutrient patterns (NPs) and their association with bone mineral density (BMD) categories in postmenopausal women. The results showed that lower consumption of NP1 and NP2 was associated with an increased risk of osteopenia, but not osteoporosis.
Article
Sport Sciences
Annie M. Skinner, Dimitris Vlachopoulos, Alan R. Barker, Sarah A. Moore, Alex Rowlands, Sonja Soininen, Eero A. Haapala, Juuso Vaisto, Kate Westgate, Soren Brage, Timo A. Lakka
Summary: The study aimed to assess the associations of physical activity (PA) volume, PA intensity distribution, and moderate-to-vigorous PA (MVPA) with bone mineral content, lean mass, and fat mass in children. The results showed that PA volume was positively associated with bone mineral content in both females and males, and positively associated with lean mass (males) or negatively associated with fat mass (males). PA intensity was negatively associated with bone mineral content in males. MVPA was positively associated with lean mass and negatively associated with fat mass in both females and males.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Sport Sciences
Philip D. Chilibeck, Darren G. Candow, Julianne J. Gordon, Whitney R. D. Duff, Riley Mason, Keely Shaw, Regina Taylor-Gjevre, Bindu Nair, Gordon A. Zello
Summary: Two years of creatine supplementation and exercise had no effect on bone mineral density in postmenopausal women, but improved some bone geometric properties at the proximal femur.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Endocrinology & Metabolism
Katherine W. Reeves, Gabriela Vieyra, Nydjie P. Grimes, Jaymie Meliker, Rebecca D. Jackson, Jean Wactawski-Wende, Robert Wallace, R. Thomas Zoeller, Carol Bigelow, Susan E. Hankinson, JoAnn E. Manson, Jane A. Cauley, Antonia M. Calafat
Summary: The study found that certain phthalate biomarkers were associated with greater percentage decreases in total hip and femoral neck bone mineral density (BMD), suggesting that phthalate exposure may have clinically significant effects on BMD and potentially increase fracture risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Biochemistry & Molecular Biology
Graziamaria Corbi, Vincenzo Nobile, Valeria Conti, Alessandro Cannavo, Vincenzo Sorrenti, Alessandro Medoro, Giovanni Scapagnini, Sergio Davinelli
Summary: This study aimed to evaluate the effects of equol and resveratrol on bone turnover biomarkers in postmenopausal women. The results showed that the combination of equol and resveratrol significantly improved bone turnover biomarkers and increased bone mineral density, suggesting a potential approach to prevent age-related bone loss in postmenopausal women.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Joseph C. Wong, Sheila O'Neill, Belinda R. Beck, Mark R. Forwood, Soo Keat Khoo
Summary: This study found that obesity classified using percentage body fat (PBF) was more severe than using body mass index (BMI) and fat mass index (FMI), possibly due to its lower predetermined threshold. Additionally, from the age of 50-59, the difference between PBF and BMI/FMI was greater, which may be attributed to age-related lean mass loss.
Article
Immunology
Cheng Peng, Feng Liu, Kuan-Jui Su, Xu Lin, Yu-Qian Song, Jie Shen, Shi-Di Hu, Qiao-Cong Chen, Hui-Hui Yuan, Wen-Xi Li, Chun-Ping Zeng, Hong-Wen Deng, Hui-Ling Lou
Summary: Strong relationships were found between appendicular lean mass (ALM) and bone mineral density (BMD). Leveraging pleiotropy with BMD, this study identified 26 novel potential pleiotropic SNPs for ALM. Through a combined analysis of two large independent genome wide association studies, this research demonstrated the efficiency and reliability of the cFDR methodology in detecting trait-associated genetic variants for ALM.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Endocrinology & Metabolism
Julien Paccou, Sammy Badr, Daniela Lombardo, Huda Khizindar, Valerie Deken, Stefan Ruschke, Dimitrios C. Karampinos, Anne Cotten, Bernard Cortet
Summary: This study aimed to determine the association between proton density fat fraction (PDFF) and fractures. A case-control study was conducted on postmenopausal women, and it was found that MRI-based measurement of proximal femur PDFF can discriminate between postmenopausal women with and without clinical vertebral fractures, independent of age, CCI, and BMD.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Nutrition & Dietetics
Pilar Sanchis, Rafael Maria Prieto, Jadwiga Konieczna, Felix Grases, Itziar Abete, Jordi Salas-Salvado, Vicente Martin, Miguel Ruiz-Canela, Nancy Babio, Jesus Francisco Garcia-Gavilan, Albert Goday, Antonia Costa-Bauza, Jose Alfredo Martinez, Dora Romaguera
Summary: The main objective of this study was to examine the relationship between dietary phytate intake and bone mineral density (BMD) in a Mediterranean population of postmenopausal women. The results showed that phytate intake was positively associated with BMD in Mediterranean postmenopausal women, indicating a potential protective effect on bone. However, further large-scale, long-term, and randomized prospective clinical studies are needed to assess the potential benefits of phytate consumption on BMD in postmenopausal women.