Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke

Effects of SPAK knockout on sensorimotor gating, novelty exploration, and brain area-dependent expressions of NKCC1 and KCC2 in a mouse model of schizophrenia

(2015) Sung-Sen Yang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke

(2015) Gulnaz Begum et al.   STROKE

Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters

(2014) E. Kikuchi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

(2014) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

The WNK-SPAK/OSR1 pathway: Master regulator of cation-chloride cotransporters

(2014) D. R. Alessi et al.   Science Signaling

Brain Edema Predicts Outcome After Nonlacunar Ischemic Stroke

(2014) Thomas W.K. Battey et al.   STROKE

Recommendations for the Management of Cerebral and Cerebellar Infarction With Swelling

(2014) Eelco F. M. Wijdicks et al.   STROKE

Identification of a Potent Sodium Hydrogen Exchanger Isoform 1 (NHE1) Inhibitor with a Suitable Profile for Chronic Dosing and Demonstrated Cardioprotective Effects in a Preclinical Model of Myocardial Infarction in the Rat

(2012) John D. Huber et al.   JOURNAL OF MEDICINAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Molecular Physiology of SPAK and OSR1: Two Ste20-Related Protein Kinases Regulating Ion Transport

(2012) Kenneth B. Gagnon et al.   PHYSIOLOGICAL REVIEWS

A SPAK Isoform Switch Modulates Renal Salt Transport and Blood Pressure

(2011) James A. McCormick et al.   Cell Metabolism

WNK2 Kinase Is a Novel Regulator of Essential Neuronal Cation-Chloride Cotransporters

(2011) Jesse Rinehart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The WNK Kinase Network Regulating Sodium, Potassium, and Blood Pressure

(2011) E. J. Hoorn et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Impaired phosphorylation of Na+-K+-2Cl- cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome

(2011) S.-H. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo

(2011) K. Oi et al.   Biology Open

Inhibition of Na+/H+ Exchanger Isoform 1 Is Neuroprotective in Neonatal Hypoxic Ischemic Brain Injury

(2010) Pelin Cengiz et al.   ANTIOXIDANTS & REDOX SIGNALING

Behavioral analysis of Ste20 kinase SPAK knockout mice

(2009) Yang Geng et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of gemfibrozil on outcome after permanent middle cerebral artery occlusion in mice

(2009) Qingmin Guo et al.   BRAIN RESEARCH

Protein aggregation in neurons following OGD: a role for Na+and Ca2+ionic dysregulation

(2009) Xinzhi Chen et al.   JOURNAL OF NEUROCHEMISTRY

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice

(2009) Valentine Bouet et al.   Nature Protocols

Molecular Physiology of the WNK Kinases

(2007) Kristopher T. Kahle et al.   Annual Review of Physiology