Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function

Seizure control by decanoic acid through direct AMPA receptor inhibition

(2015) Pishan Chang et al.   BRAIN

Sulforaphane is anticonvulsant and improves mitochondrial function

(2015) Catalina Carrasco-Pozo et al.   JOURNAL OF NEUROCHEMISTRY

A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models

(2015) Melissa J. Benson et al.   NEUROBIOLOGY OF DISEASE

Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin

(2015) T.M. Schwarzkopf et al.   NEUROSCIENCE

Acute anticonvulsant effects of capric acid in seizure tests in mice

(2015) Piotr Wlaź et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells

(2014) Sean David Hughes et al.   JOURNAL OF NEUROCHEMISTRY

Triheptanoin for Glucose Transporter Type I Deficiency (G1D)

(2014) Juan M. Pascual et al.   JAMA Neurology

A FoxO1-dependent, but NRF2-independent induction of heme oxygenase-1 during muscle atrophy

(2013) Jione Kang et al.   FEBS LETTERS

Alterations of Hippocampal Glucose Metabolism by Even versus Uneven Medium Chain Triglycerides

(2013) Tanya S McDonald et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy

(2013) Mussie G. Hadera et al.   JOURNAL OF NEUROCHEMISTRY

Power failure: why small sample size undermines the reliability of neuroscience

(2013) Katherine S. Button et al.   NATURE REVIEWS NEUROSCIENCE

Cobalt Protoporphyrin Induces HO-1 Expression Mediated Partially by FOXO1 and Reduces Mitochondria-Derived Reactive Oxygen Species Production

(2013) Xiaojun Liu et al.   PLoS One

Triheptanoin in acute mouse seizure models

(2012) Nicola K. Thomas et al.   EPILEPSY RESEARCH

Heptanoate as a Neural Fuel: Energetic and Neurotransmitter Precursors in Normal and Glucose Transporter I-Deficient (G1D) Brain

(2012) Isaac Marin-Valencia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells

(2012) Jin Zhang et al.   Nature Protocols

Seizure control by ketogenic diet-associated medium chain fatty acids

(2012) Pishan Chang et al.   NEUROPHARMACOLOGY

Comparison of native and capric acid-enriched mustard oil effects on oxidative stress and antioxidant protection in rats

(2011) Avery Sengupta et al.   BRITISH JOURNAL OF NUTRITION

Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics

(2011) Ryan J. Mailloux et al.   FASEB JOURNAL

Cortical Substrate Oxidation during Hyperketonemia in the Fasted Anesthetized Rat in Vivo

(2011) Lihong Jiang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice

(2011) Piotr Wlaź et al.   NEUROPHARMACOLOGY

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

Capric Acid Inhibits NO Production and STAT3 Activation during LPS-Induced Osteoclastogenesis

(2011) Eun-Jung Park et al.   PLoS One

Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models

(2010) Sarah Willis et al.   NEUROBIOLOGY OF DISEASE

The ketogenic diet changes metabolite levels in hippocampal extracellular fluid

(2010) Ramakrishna Samala et al.   NEUROCHEMISTRY INTERNATIONAL

Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile

(2009) Lei Gu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Triglyceride Synthesis in Epididymal Adipose Tissue

(2008) Ilya R. Bederman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY