Apigenin Reduces Survival of Choriocarcinoma Cells by Inducing Apoptosis via the PI3K/AKT and ERK1/2 MAPK Pathways

Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1expression

(2016) Tsui-Hwa Tseng et al.   ENVIRONMENTAL TOXICOLOGY

FBI-1 Is Overexpressed in Gestational Trophoblastic Disease and Promotes Tumor Growth and Cell Aggressiveness of Choriocarcinoma via PI3K/Akt Signaling

(2015) Victor C.Y. Mak et al.   AMERICAN JOURNAL OF PATHOLOGY

Nuclear localized Akt enhances breast cancer stem-like cells through counter-regulation of p21Waf1/Cip1and p27kip1

(2015) Mayur Vilas Jain et al.   CELL CYCLE

The Flavonoid Apigenin Ameliorates Cisplatin-Induced Nephrotoxicity through Reduction of p53 Activation and Promotion of PI3K/Akt Pathway in Human Renal Proximal Tubular Epithelial Cells

(2015) Sung Min Ju et al.   Evidence-based Complementary and Alternative Medicine

Epidermal growth factor-like domain 7 promotes migration and invasion of human trophoblast cells through activation of MAPK, PI3K and NOTCH signaling pathways

(2015) M. Massimiani et al.   MOLECULAR HUMAN REPRODUCTION

Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer

(2015) Jin-Soo Kim et al.   Oncotarget

Targeting the PI3K/Akt/mTOR Axis by Apigenin for Cancer Prevention

(2013) Xin Tong et al.   Anti-Cancer Agents in Medicinal Chemistry

Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation

(2013) V. C. Y. Mak et al.   CARCINOGENESIS

Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway

(2013) S. Shukla et al.   CARCINOGENESIS

Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: Mitochondria mediated apoptotic signalling cascades

(2013) Sreemanti Das et al.   FOOD AND CHEMICAL TOXICOLOGY

N-Myc knockdown and apigenin treatment controlled growth of malignant neuroblastoma cells having N-Myc amplification

(2013) Md. Motarab Hossain et al.   GENE

IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1

(2013) Yeun-Ting Hsieh et al.   GYNECOLOGIC ONCOLOGY

Apigenin induces c-Myc-mediated apoptosis in FRO anaplastic thyroid carcinoma cells

(2013) Si Hyoung Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling

(2013) Kazuhiro Kawamura et al.   Cancer Medicine

Purified Vitexin Compound 1 Suppresses Tumor Growth and Induces Cell Apoptosis in a Mouse Model of Human Choriocarcinoma

(2012) Zhihui Tan et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90

(2011) Ming Zhao et al.   Molecular Cancer

Apigenin Attenuates Insulin-Like Growth Factor-I Signaling in an Autochthonous Mouse Prostate Cancer Model

(2011) Sanjeev Shukla et al.   PHARMACEUTICAL RESEARCH

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Apigenin induces apoptosis in human lung cancer H460 cells through caspase- and mitochondria-dependent pathways

(2010) Hsu-Feng Lu et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Methotrexate induces apoptosis of human choriocarcinoma cell line JAR via a mitochondrial pathway

(2009) Ya-Xia Chen et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways

(2008) Jai-Sing Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Apigenin suppresses insulin-like growth factor I receptor signaling in human prostate cancer: An in vitro and in vivo study

(2008) Sanjeev Shukla et al.   MOLECULAR CARCINOGENESIS