Resistance to 3-HTMC-Induced Apoptosis Through Activation of PI3K/Akt, MEK/ERK, and p38/COX-2/PGE2Pathways in Human HT-29 and HCT116 Colorectal Cancer Cells

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Autophagy-Mediated Degradation of IAPs and c-FLIPL Potentiates Apoptosis Induced by Combination of TRAIL and Chal-24

(2015) Jennings Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Upregulation of PI3K/Akt and MAP Kinase Pathways is Associated with Resistance of Microtubule-Targeting Drugs in Prostate Cancer

(2015) Zhi Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Molecular Targeted Approaches to Cancer Therapy and Prevention Using Chalcones

(2014) Danielle Jandial et al.   CURRENT CANCER DRUG TARGETS

Chalcones with electron-withdrawing and electron-donating substituents: Anticancer activity against TRAIL resistant cancer cells, structure–activity relationship analysis and regulation of apoptotic proteins

(2014) Chun Wai Mai et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclooxygenase-2 positively regulates Akt signalling and enhances survival of erythroleukemia cells exposed to anticancer agents

(2013) Julian Bertrand et al.   APOPTOSIS

The chalcone 2′-hydroxy-4′,5′-dimethoxychalcone activates death receptor 5 pathway and leads to apoptosis in human nonsmall cell lung cancer cells

(2013) Lina Yang et al.   IUBMB LIFE

The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells

(2012) Youness Limami et al.   BIOCHIMIE

HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death

(2011) Youness Limami et al.   BIOCHIMIE

Dietary chalcones with chemopreventive and chemotherapeutic potential

(2011) Barbora Orlikova et al.   Genes and Nutrition

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells

(2010) C. Lepage et al.   CANCER LETTERS

Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth

(2010) Yaxiong Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Activation of the PI3K/Akt and MAPK signaling pathways antagonizes adriamycin-induced HL-60 leukemia cell apoptosis

(2010) Zhou   Molecular Medicine Reports

Synthesis and biological evaluation of 3′,4′,5′-trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation

(2009) Yerra Koteswara Rao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity

(2009) Sylvie Ducki et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Chalcones Derivatives Acting as Cell Cycle Blockers: Potential Anti Cancer Drugs?

(2009) Boumendjel Ahcene et al.   CURRENT DRUG TARGETS

A review on plant-derived natural products and their analogs with anti-tumor activity

(2009) KK Dholwani et al.   INDIAN JOURNAL OF PHARMACOLOGY

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

Natural compounds for cancer treatment and prevention

(2009) Stefania Nobili et al.   PHARMACOLOGICAL RESEARCH

Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors

(2009) Fatima Haggar et al.   Clinics in Colon and Rectal Surgery

Current overview of the role of Akt in cancer studies via applied immunohistochemistry

(2008) Viktor Shtilbans et al.   Annals of Diagnostic Pathology

Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells

(2008) Tatsushi Yoshida et al.   Environmental Health and Preventive Medicine