A Computational Protein Phenotype Prediction Approach to Analyze the Deleterious Mutations of Human MED12 Gene

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Computational Identification of Pathogenic Associated nsSNPs and its Structural Impact in UROD Gene: A Molecular Dynamics Approach

(2014) C. George Priya Doss et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Structural and Functional Characterization of Pathogenic Non- Synonymous Genetic Mutations of Human Insulin-Degrading Enzyme by In Silico Methods

(2014) Noor Shaik et al.   CNS & Neurological Disorders-Drug Targets

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity

(2014) Mikko Turunen et al.   Cell Reports

The Mediator complex and transcription regulation

(2013) Zachary C. Poss et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Progress in Detecting Genetic Alterations and Their Association with Human Disease

(2013) Charles E. Schwartz et al.   JOURNAL OF MOLECULAR BIOLOGY

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

(2013) Fan Lai et al.   NATURE

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

In silico analysis of Single Nucleotide Polymorphisms (SNPs) in human BRAF gene

(2012) Muhammad Ramzan Manwar Hussain et al.   GENE

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

(2012) Christopher E Barbieri et al.   NATURE GENETICS

Computational Refinement of Functional Single Nucleotide Polymorphisms Associated with ATM Gene

(2012) C. George Priya Doss et al.   PLoS One

Computational Methods to Work as First-Pass Filter in Deleterious SNP Analysis of Alkaptonuria

(2012) R. Magesh et al.   TheScientificWorldJOURNAL

Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed

(2011) Stephanie Hicks et al.   HUMAN MUTATION

MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

(2011) N. Makinen et al.   SCIENCE

Mediator and human disease

(2011) Jason M. Spaeth et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Novel missense mutations in the ubiquitination-related geneUBE2Acause a recognizable X-linked mental retardation syndrome

(2010) B Budny et al.   CLINICAL GENETICS

Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling

(2010) P. P. Rocha et al.   DEVELOPMENT

Performance of protein stability predictors

(2010) Sofia Khan et al.   HUMAN MUTATION

The human Mediator complex: a versatile, genome-wide regulator of transcription

(2010) Dylan J. Taatjes   TRENDS IN BIOCHEMICAL SCIENCES

Function and regulation of the mammalian Musashi mRNA translational regulator

(2008) Angus M. MacNicol et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Human CDK8 Subcomplex Is a Histone Kinase That Requires Med12 for Activity and Can Function Independently of Mediator

(2008) M. T. Knuesel et al.   MOLECULAR AND CELLULAR BIOLOGY

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE