Macrophages of genetically characterized familial hypercholesterolaemia patients show up-regulation of LDL-receptor-related proteins

LDL accelerates monocyte to macrophage differentiation: Effects on adhesion and anoikis

(2016) R. Escate et al.   ATHEROSCLEROSIS

LRP5 associates with specific subsets of macrophages: Molecular and functional effects

(2016) M. Borrell-Pages et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

LRP5 and plasma cholesterol levels modulate the canonical Wnt pathway in peripheral blood leukocytes

(2015) Maria Borrell-Pages et al.   IMMUNOLOGY AND CELL BIOLOGY

LRP5 deficiency down-regulates Wnt signalling and promotes aortic lipid infiltration in hypercholesterolaemic mice

(2015) Maria Borrell-Pagès et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cholesterol modulates LRP5 expression in the vessel wall

(2014) M. Borrell-Pages et al.   ATHEROSCLEROSIS

β-Catenin–regulated myeloid cell adhesion and migration determine wound healing

(2014) Saeid Amini-Nik et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrated guidance on the care of familial hypercholesterolemia from the International FH Foundation

(2014) Gerald F. Watts et al.   Journal of Clinical Lipidology

Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway

(2014) Stephen A. Ramsey et al.   PLoS Genetics

UPA promotes lipid-loaded vascular smooth muscle cell migration through LRP-1

(2013) Roberta Lugano et al.   CARDIOVASCULAR RESEARCH

LRP5 negatively regulates differentiation of monocytes through abrogation of Wnt signalling

(2013) Maria Borrell-Pagès et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A DNA Microarray for the Detection of Point Mutations and Copy Number Variation Causing Familial Hypercholesterolemia in Europe

(2013) Marianne A. Stef et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition

(2013) Ryan C. Riddle et al.   PLoS One

Circulating CD45+/CD3+ lymphocyte-derived microparticles map lipid-rich atherosclerotic plaques in familial hypercholesterolaemia patients

(2013) R. Suades et al.   THROMBOSIS AND HAEMOSTASIS

Detection of subclinical atherosclerosis in familial hypercholesterolemia using non-invasive imaging modalities

(2012) Paloma Caballero et al.   ATHEROSCLEROSIS

Human monocyte-derived macrophages spontaneously differentiated in vitro show distinct phenotypes

(2012) Sonia Eligini et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer

(2012) Sofia Edin et al.   PLoS One

Recently Infiltrating MAC387+ Monocytes/Macrophages

(2011) Caroline Soulas et al.   AMERICAN JOURNAL OF PATHOLOGY

Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

(2011) Jonathan E. Feig et al.   CIRCULATION

Wnt pathway activation, cell migration, and lipid uptake is regulated by low-density lipoprotein receptor-related protein 5 in human macrophages

(2011) Maria Borrell-Pagès et al.   EUROPEAN HEART JOURNAL

Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART)

(2011) Nelva Mata et al.   Lipids in Health and Disease

Lrp5 functions in bone to regulate bone mass

(2011) Yajun Cui et al.   NATURE MEDICINE

Sample Size Calculations

(2011) Marlies Noordzij et al.   NEPHRON CLINICAL PRACTICE

HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells

(2011) J. E. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils, Hypercholesterolemia, and Atherogenesis

(2010) Stanley L. Hazen   CIRCULATION

Coronary Intraplaque Hemorrhage Evokes a Novel Atheroprotective Macrophage Phenotype

(2009) Joseph J. Boyle et al.   AMERICAN JOURNAL OF PATHOLOGY

Genetic diagnosis of familial hypercholesterolemia using a DNA-array based platform

(2009) Rodrigo Alonso et al.   CLINICAL BIOCHEMISTRY

Carotid artery atherosclerosis in hypertensive patients with a functional LDL receptor-related protein 6 gene variant

(2009) R. Sarzani et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Cardiovascular disease in familial hypercholesterolaemia: Influence of low-density lipoprotein receptor mutation type and classic risk factors

(2008) R. Alonso et al.   ATHEROSCLEROSIS

Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism

(2008) Sandy Mosig et al.   BMC Medical Genomics

Different functions of monocyte subsets in familial hypercholesterolemia: potential function of CD14+CD16+ monocytes in detoxification of oxidized LDL

(2008) Sandy Mosig et al.   FASEB JOURNAL