Tensin 3 is a new partner of Dock5 that controls osteoclast podosome organization and activity

Tensin1 positively regulates RhoA activity through its interaction with DLC1

(2015) Yi-Ping Shih et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pharmacological inhibition of Dock5 prevents osteolysis by affecting osteoclast podosome organization while preserving bone formation

(2015) Virginie Vives et al.   Nature Communications

A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration

(2015) Xuan Cao et al.   Nature Communications

The mineral dissolution function of osteoclasts is dispensable for hypertrophic cartilage degradation during long bone development and growth

(2014) Heiani Touaitahuata et al.   DEVELOPMENTAL BIOLOGY

Dock-family exchange factors in cell migration and disease

(2014) Gilles Gadea et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Podosomes revealed by advanced bioimaging: What did we learn?

(2014) Marjolein B.M. Meddens et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Vinculin Regulates Osteoclast Function

(2014) Tomohiro Fukunaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Podosome organization drives osteoclast-mediated bone resorption

(2014) Dan Georgess et al.   Cell Adhesion & Migration

p130Cas, Crk-Associated Substrate, Plays Important Roles in Osteoclastic Bone Resorption

(2013) Yoshie Nagai et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Microtubule Dynamic Instability Controls Podosome Patterning in Osteoclasts through EB1, Cortactin, and Src

(2013) M. Biosse Duplan et al.   MOLECULAR AND CELLULAR BIOLOGY

Talin1 and Rap1 Are Critical for Osteoclast Function

(2012) W. Zou et al.   MOLECULAR AND CELLULAR BIOLOGY

Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation

(2012) X. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rac deletion in osteoclasts causes severe osteopetrosis

(2011) M. Croke et al.   JOURNAL OF CELL SCIENCE

Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements

(2010) Noriko Takegahara et al.   FASEB JOURNAL

The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

(2010) Virginie Vives et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Tensin-3 Protein, Including its SH2 Domain, Is Phosphorylated by Src and Contributes to Tumorigenesis and Metastasis

(2009) Xiaolan Qian et al.   CANCER CELL

Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia

(2009) Minna Takkunen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tensin3 Is a Negative Regulator of Cell Migration and All Four Tensin Family Members Are Downregulated in Human Kidney Cancer

(2009) Danuta Martuszewska et al.   PLoS One

Rho GTPases in osteoclasts: Orchestrators of podosome arrangement

(2008) S ORY et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The Rho GTPase Wrch1 regulates osteoclast precursor adhesion and migration

(2008) Hélène Brazier et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

An α-Helical Extension of the ELMO1 Pleckstrin Homology Domain Mediates Direct Interaction to DOCK180 and Is Critical in Rac Signaling

(2008) David Komander et al.   MOLECULAR BIOLOGY OF THE CELL

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo

(2008) M. Laurin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts

(2007) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL