Rac1/RhoA antagonism defines cell-to-cell heterogeneity during epidermal morphogenesis in nematodes

P-cadherin promotes collective cell migration via a Cdc42-mediated increase in mechanical forces

(2016) Cédric Plutoni et al.   JOURNAL OF CELL BIOLOGY

Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches

(2016) Kate M. Byrne et al.   Cell Systems

Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis ofC. elegans

(2015) Elise Walck-Shannon et al.   DEVELOPMENT

Local and tissue-scale forces drive oriented junction growth during tissue extension

(2015) Claudio Collinet et al.   NATURE CELL BIOLOGY

E-cadherin junctions as active mechanical integrators in tissue dynamics

(2015) Thomas Lecuit et al.   NATURE CELL BIOLOGY

Actomyosin networks and tissue morphogenesis

(2014) Akankshi Munjal et al.   DEVELOPMENT

Distinct Apical and Basolateral Mechanisms Drive Planar Cell Polarity-Dependent Convergent Extension of the Mouse Neural Plate

(2014) Margot Williams et al.   DEVELOPMENTAL CELL

Rho1 regulates adherens junction remodeling by promoting recycling endosome formation through activation of myosin II

(2014) Hanako Yashiro et al.   MOLECULAR BIOLOGY OF THE CELL

Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions

(2014) W. Engl et al.   NATURE CELL BIOLOGY

pix-1 Controls Early Elongation in Parallel with mel-11 and let-502 in Caenorhabditis elegans

(2014) Emmanuel Martin et al.   PLoS One

Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity

(2014) H. Sailem et al.   Open Biology

FilGAP and its close relatives: a mediator of Rho–Rac antagonism that regulates cell morphology and migration

(2013) Fumihiko Nakamura   BIOCHEMICAL JOURNAL

Regulation of Focal Adhesion Kinase Activation, Breast Cancer Cell Motility, and Amoeboid Invasion by the RhoA Guanine Nucleotide Exchange Factor Net1

(2013) H. S. Carr et al.   MOLECULAR AND CELLULAR BIOLOGY

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

(2013) Zheng Yin et al.   NATURE CELL BIOLOGY

Filopodia and Membrane Blebs Drive Efficient Matrix Invasion of Macrophages Transformed by the Intracellular Parasite Theileria annulata

(2013) Min Ma et al.   PLoS One

ROCK1 and ROCK2 regulate epithelial polarisation and geometric cell shape

(2012) Ruba Kalaji et al.   BIOLOGY OF THE CELL

FilGAP, a Rho/Rho-associated protein kinase–regulated GTPase-activating protein for Rac, controls tumor cell migration

(2012) Koji Saito et al.   MOLECULAR BIOLOGY OF THE CELL

The topology design principles that determine the spatiotemporal dynamics of G-protein cascades

(2012) Mikhail A. Tsyganov et al.   Molecular BioSystems

A Bistable Model of Cell Polarity

(2012) Matteo Semplice et al.   PLoS One

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

(2011) Gregory F. Weber et al.   DEVELOPMENTAL CELL

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front–back polarity in migrating cells

(2011) Miguel Vicente-Manzanares et al.   JOURNAL OF CELL BIOLOGY

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

(2011) Huimin Zhang et al.   NATURE

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis

(2011) Romain Levayer et al.   NATURE CELL BIOLOGY

Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia

(2011) B. K. Chauhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-ECM traction force modulates endogenous tension at cell-cell contacts

(2011) V. Maruthamuthu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Pak1 control of E-cadherin endocytosis regulates salivary gland lumen size and shape

(2010) C. Pirraglia et al.   DEVELOPMENT

Genetic Evidence for Antagonism Between Pak Protein Kinase and Rho1 Small GTPase Signaling in Regulation of the Actin Cytoskeleton During Drosophila Oogenesis

(2010) S. Vlachos et al.   GENETICS

Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions

(2010) M. Georgiou et al.   JOURNAL OF CELL SCIENCE

Spatio-temporal Rho GTPase signaling - where are we now?

(2010) O. Pertz   JOURNAL OF CELL SCIENCE

Cadherins and Pak1 Control Contact Inhibition of Proliferation by Pak1- PIX-GIT Complex-Dependent Regulation of Cell-Matrix Signaling

(2010) F. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets

(2010) Hanchuan Peng et al.   NATURE BIOTECHNOLOGY

Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles

(2009) C. Gally et al.   DEVELOPMENT

Distinct Roles for RhoVersusRac/Cdc42 GTPases Downstream of Vav2 in Regulating Mammary Epithelial Acinar Architecture

(2009) Lei Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Rac and Rho driving tumor invasion: who's at the wheel?

(2009) Marc Symons et al.   GENOME BIOLOGY

Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

(2008) Andrew J. Ewald et al.   DEVELOPMENTAL CELL

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

(2008) Matteo Rauzi et al.   NATURE CELL BIOLOGY