Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth

Assembly of hair bundles, an amazing problem for cell biology

(2015) Peter-G. Barr-Gillespie   MOLECULAR BIOLOGY OF THE CELL

Invertebrate and Vertebrate Class III Myosins Interact with MORN Repeat-Containing Adaptor Proteins

(2015) Kirk L. Mecklenburg et al.   PLoS One

Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

(2015) Meghan C. Drummond et al.   Nature Communications

Single-molecule imaging of a three-component ordered actin disassembly mechanism

(2015) Silvia Jansen et al.   Nature Communications

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

(2015) Praveena Narayanan et al.   Nature Communications

The Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In Vivo

(2015) Philsang Hwang et al.   Cell Reports

Physical Model for the Geometry of Actin-Based Cellular Protrusions

(2014) G. Orly et al.   BIOPHYSICAL JOURNAL

The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells

(2014) E. Pepermans et al.   EMBO Molecular Medicine

Characterization and regulation of an additional actin-filament-binding site in large isoforms of the stereocilia actin-bundling protein espin

(2014) L. Zheng et al.   JOURNAL OF CELL SCIENCE

Transduction without Tip Links in Cochlear Hair Cells Is Mediated by Ion Channels with Permeation Properties Distinct from Those of the Mechano-Electrical Transducer Channel

(2014) W. Marcotti et al.   JOURNAL OF NEUROSCIENCE

The Physiology of Mechanoelectrical Transduction Channels in Hearing

(2014) Robert Fettiplace et al.   PHYSIOLOGICAL REVIEWS

Auditory Hair Cell Centrioles Undergo Confined Brownian Motion Throughout the Developmental Migration of the Kinocilium

(2013) Léa Lepelletier et al.   BIOPHYSICAL JOURNAL

A Molecular Blueprint at the Apical Surface Establishes Planar Asymmetry in Cochlear Hair Cells

(2013) Basile Tarchini et al.   DEVELOPMENTAL CELL

The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

(2013) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton

(2013) Jerome Ezan et al.   NATURE CELL BIOLOGY

Molecular architecture of the chick vestibular hair bundle

(2013) Jung-Bum Shin et al.   NATURE NEUROSCIENCE

A balance of form and function: Planar polarity and development of the vestibular maculae

(2013) Michael R. Deans   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Myosin IIIB Uses an Actin-Binding Motif in Its Espin-1 Cargo to Reach the Tips of Actin Protrusions

(2012) Raymond C. Merritt et al.   CURRENT BIOLOGY

Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice

(2012) Iman Sahly et al.   JOURNAL OF CELL BIOLOGY

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

(2012) Duan-Sun Zhang et al.   NATURE

Regulation of Stereocilia Length by Myosin XVa and Whirlin Depends on the Actin-Regulatory Protein Eps8

(2011) Uri Manor et al.   CURRENT BIOLOGY

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

(2011) E. Caberlotto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of the Espin Actin-Bundling Proteins in the Morphogenesis and Stabilization of Hair Cell Stereocilia Revealed in CBA/CaJ Congenic Jerker Mice

(2011) Gabriella Sekerková et al.   PLoS Genetics

Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

(2010) Shin-ichiro Kitajiri et al.   CELL

A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA

(2010) Vanessa L. Walsh et al.   MAMMALIAN GENOME

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments

(2009) Felipe T. Salles et al.   NATURE CELL BIOLOGY

Linking genes underlying deafness to hair-bundle development and function

(2009) Christine Petit et al.   NATURE NEUROSCIENCE

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging

(2009) Maryline Beurg et al.   NATURE NEUROSCIENCE

PPI Finder: A Mining Tool for Human Protein-Protein Interactions

(2009) Min He et al.   PLoS One

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

(2008) G. Lefevre et al.   DEVELOPMENT

The Dimensions and Composition of Stereociliary Rootlets in Mammalian Cochlear Hair Cells: Comparison between High- and Low-Frequency Cells and Evidence for a Connection to the Lateral Membrane

(2008) D. N. Furness et al.   JOURNAL OF NEUROSCIENCE