Postnatal telomere dysfunction induces cardiomyocyte cell-cycle arrest through p21 activation

Resetting the epigenome for heart regeneration.

(2016) Gregory A. Quaife-Ryan et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Functional Recovery of a Human Neonatal Heart After Severe Myocardial InfarctionNovelty and Significance

(2015) Bernhard J. Haubner et al.   CIRCULATION RESEARCH

Telomerase Is Essential for Zebrafish Heart Regeneration

(2015) Dorota Bednarek et al.   Cell Reports

CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes

(2014) Shoji Tane et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

Regulation of cardiomyocyte proliferation during development and regeneration

(2014) Takashi Takeuchi   DEVELOPMENT GROWTH & DIFFERENTIATION

A neonatal blueprint for cardiac regeneration

(2014) Enzo R. Porrello et al.   Stem Cell Research

Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation

(2014) Samuel E. Senyo et al.   Stem Cell Research

Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

(2014) Christian Bär et al.   Nature Communications

Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population

(2014) Ru-Hua Chen et al.   Clinical Interventions in Aging

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease

(2013) Cécilia G. Maubaret et al.   PLoS One

Cardiomyocyte proliferation contributes to heart growth in young humans

(2013) Mariya Mollova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomeres shorten at equivalent rates in somatic tissues of adults

(2013) Lily Daniali et al.   Nature Communications

p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice

(2013) Darren J. Baker et al.   Cell Reports

Cardiac Regenerative Capacity and Mechanisms

(2012) Kazu Kikuchi et al.   Annual Review of Cell and Developmental Biology

Cell cycle regulation in mouse heart during embryonic and postnatal stages

(2012) Aiko Ikenishi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Telomerase expression in the mammalian heart

(2012) Gavin D. Richardson et al.   FASEB JOURNAL

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

(2012) E. R. Porrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progressive Telomere Dysfunction Causes Cytokinesis Failure and Leads to the Accumulation of Polyploid Cells

(2012) Judit Pampalona et al.   PLoS Genetics

The Causes and Consequences of Polyploidy in Normal Development and Cancer

(2011) Teresa Davoli et al.   Annual Review of Cell and Developmental Biology

Telomere dysfunction and chromosome instability

(2011) John P. Murnane   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

(2009) Yvonne Begus-Nahrmann et al.   NATURE GENETICS

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Compensatory Growth of Healthy Cardiac Cells in the Presence of Diseased Cells Restores Tissue Homeostasis during Heart Development

(2008) Jörg-Detlef Drenckhahn et al.   DEVELOPMENTAL CELL

The longest telomeres: a general signature of adult stem cell compartments

(2008) I. Flores et al.   GENES & DEVELOPMENT

Expanding the clinical phenotype of autosomal dominant dyskeratosis congenita caused by TERT mutations

(2008) L. Basel-Vanagaite et al.   HAEMATOLOGICA