Loss of m6A Methyltransferase METTL5 Promotes Cardiac Hypertrophy Through Epitranscriptomic Control of SUZ12 Expression

The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy

(2021) Youchen Yan et al.   MOLECULAR THERAPY

mRNA modifications in cardiovascular biology and disease: with a focus on m6A modification

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A comprehensive review of m6A/m6Am RNA methyltransferase structures

(2021) Stephanie Oerum et al.   NUCLEIC ACIDS RESEARCH

Long Noncoding RNA Ahit Protects Against Cardiac Hypertrophy Through SUZ12 (Suppressor of Zeste 12 Protein Homolog)-Mediated Downregulation of MEF2A (Myocyte Enhancer Factor 2A)

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The 18S ribosomal RNA m 6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila

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The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs

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The 18S rRNA m 6 A methyltransferase METTL 5 promotes mouse embryonic stem cell differentiation

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Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth

(2020) Bowen Rong et al.   Cell Reports

The N 6 -Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy

(2019) Lisa E. Dorn et al.   CIRCULATION

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112

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Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Changes in m6A RNA methylation contribute to heart failure progression by modulating translation

(2019) Tea Berulava et al.   EUROPEAN JOURNAL OF HEART FAILURE

FTO-Dependent m6A Regulates Cardiac Function During Remodeling and Repair

(2018) Prabhu Mathiyalagan et al.   CIRCULATION

eXpression2Kinases (X2K) Web: linking expression signatures to upstream cell signaling networks

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Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy

(2016) Zhihua Wang et al.   NATURE MEDICINE

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis

(2015) Zhan-Peng Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

deepTools: a flexible platform for exploring deep-sequencing data

(2014) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

CIP, a Cardiac Isl1-Interacting Protein, Represses Cardiomyocyte Hypertrophy

(2012) Zhan-Peng Huang et al.   CIRCULATION RESEARCH

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice

(2008) Yuri Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanotransduction gone awry

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Cardiac Plasticity

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