MicroRNA-495 suppresses pre-eclampsia via activation of p53/PUMA axis

Pre-eclampsia: pathogenesis, novel diagnostics and therapies

(2019) Elizabeth A. Phipps et al.   Nature Reviews Nephrology

A double-hit pre-eclampsia model results in sex-specific growth restriction patterns

(2019) Violeta Stojanovska et al.   Disease Models & Mechanisms

Microarray meta‐analysis identifies candidate genes for human spermatogenic arrest

(2019) Fang Kui et al.   ANDROLOGIA

Silence of miR‐494 impairs neurotoxic Th1 shift via regulating STAT4‐STAT4 cascade in ischemic stroke

(2019) Haiping Zhao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of HIF-1a-mediated TLR4 activation decreases apoptosis and promotes angiogenesis of placental microvascular endothelial cells during severe pre-eclampsia pathogenesis

(2019) Lina Zhao et al.   PLACENTA

Regulation of calpain 2 expression by miR-223 and miR-145

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Bone morphogenetic protein 2 induces the activation of WNT/β-catenin signaling and human trophoblast invasion through up-regulating BAMBI

(2019) Hong-Jin Zhao et al.   CELLULAR SIGNALLING

Up-regulation of miR-299 suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting HDAC2 in pre-eclampsia

(2018) Yu Gao et al.   BIOMEDICINE & PHARMACOTHERAPY

MiR-455-3p activates Nrf2/ARE signaling via HDAC2 and protects osteoblasts from oxidative stress

(2018) Shijun Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

MicroRNA-218-5p promotes endovascular trophoblast differentiation and spiral artery remodeling

(2018) J. Brkić et al.   MOLECULAR THERAPY

Role of mesenchymal stem cells exosomes derived microRNAs; miR-136, miR-494 and miR-495 in pre-eclampsia diagnosis and evaluation

(2018) Tarek M.k. Motawi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

MicroRNA-454 is involved in regulating trophoblast cell proliferation, apoptosis, and invasion in preeclampsia by modulating the expression of ephrin receptor B4

(2018) Furong Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA-423–5p inhibits the progression of trophoblast cells via targeting IGF2BP1

(2018) Li Guo et al.   PLACENTA

Long Non-Coding RNA Uc.187 Is Upregulated in Preeclampsia and Modulates Proliferation, Apoptosis, and Invasion of HTR-8/SVneo Trophoblast Cells

(2017) Chunyu Cao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

HDAC2 was involved in placental P-glycoprotein regulation both in vitro and vivo

(2017) Hongyu Duan et al.   PLACENTA

Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation

(2017) Kalpesh D. Mahajan et al.   Biotechnology Journal

Upregulation of P53 promoted G1 arrest and apoptosis in human umbilical cord vein endothelial cells from preeclampsia

(2016) Qinqin Gao et al.   JOURNAL OF HYPERTENSION

MicroRNA expression pattern in pre-eclampsia (Review)

(2016) DEEBA S. JAIRAJPURI et al.   Molecular Medicine Reports

Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium

(2015) S. Chen et al.   DEVELOPMENT

USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2

(2015) Z Li et al.   ONCOGENE

The Effects of Class-Specific Histone Deacetylase Inhibitors on the Development of Limbs During Organogenesis

(2015) France-Hélène Paradis et al.   TOXICOLOGICAL SCIENCES

Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation

(2015) Sung-Keum Seo et al.   Oncotarget

p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis

(2015) Wei Wang et al.   Scientific Reports

Pre-eclampsia part 1: current understanding of its pathophysiology

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

Pre-eclampsia part 2: prediction, prevention and management

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

(2014) Andrew N. Sharp et al.   PLoS One

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design combating pre-eclampsia

(2013) B. Huppertz et al.   HUMAN REPRODUCTION UPDATE

Evidence of sexual dimorphism in the placental function with severe preeclampsia

(2013) S. Muralimanoharan et al.   PLACENTA

Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress

(2012) André Brandl et al.   Journal of Molecular Cell Biology

The definition of severe and early-onset preeclampsia. Statements from the International Society for the Study of Hypertension in Pregnancy (ISSHP)

(2012) Andrea L. Tranquilli et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

A cyano analogue of boswellic acid induces crosstalk between p53/PUMA/Bax and telomerase that stages the human papillomavirus type 18 positive HeLa cells to apoptotic death

(2011) Sheema Khan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An immunological insight into the origins of pre-eclampsia

(2010) E. Laresgoiti-Servitje et al.   HUMAN REPRODUCTION UPDATE