Acceleration of enzymatic catalysis by active hydrodynamic fluctuations

Active Trap Model

(2020) Eric Woillez et al.   PHYSICAL REVIEW LETTERS

Nonlocal stationary probability distributions and escape rates for an active Ornstein–Uhlenbeck particle

(2020) Eric Woillez et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT

Boosted molecular mobility during common chemical reactions

(2020) Huan Wang et al.   SCIENCE

Stick–slip model for actin-driven cell protrusions, cell polarization, and crawling

(2020) Pierre Sens   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active escape dynamics: The effect of persistence on barrier crossing

(2019) Lorenzo Caprini et al.   JOURNAL OF CHEMICAL PHYSICS

Self-propelled particle in a nonconvex external potential: Persistent limit in one dimension

(2019) Yaouen Fily   JOURNAL OF CHEMICAL PHYSICS

Simple mechanics of protein machines

(2019) Holger Flechsig et al.   Journal of the Royal Society Interface

Activated Escape of a Self-Propelled Particle from a Metastable State

(2019) E. Woillez et al.   PHYSICAL REVIEW LETTERS

Colloquium : Proteins: The physics of amorphous evolving matter

(2019) Jean-Pierre Eckmann et al.   REVIEWS OF MODERN PHYSICS

Fluctuations of Electric Fields in the Active Site of the Enzyme Ketosteroid Isomerase

(2019) Valerie Vaissier Welborn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Active Mechanics Reveal Molecular-Scale Force Kinetics in Living Oocytes

(2018) Wylie W. Ahmed et al.   BIOPHYSICAL JOURNAL

Shewanella oneidensisas a living electrode for controlled radical polymerization

(2018) Gang Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct observation of ultrafast large-scale dynamics of an enzyme under turnover conditions

(2018) Haim Yuval Aviram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Living Matter: Mesoscopic Active Materials

(2018) Anne Bernheim-Groswasser et al.   ADVANCED MATERIALS

Electric Fields and Fast Protein Dynamics in Enzymes

(2017) Ioanna Zoi et al.   Journal of Physical Chemistry Letters

Enhanced Diffusion of Passive Tracers in Active Enzyme Solutions

(2017) Xi Zhao et al.   NANO LETTERS

Enzyme leaps fuel antichemotaxis

(2017) Ah-Young Jee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of active fluctuations on the dynamics of particles, motors and DNA-hairpins

(2017) Hans Vandebroek et al.   Soft Matter

Enzyme Catalysis To Power Micro/Nanomachines

(2016) Xing Ma et al.   ACS Nano

Mechanical Folding and Unfolding of Protein Barnase at the Single-Molecule Level

(2016) Anna Alemany et al.   BIOPHYSICAL JOURNAL

Nonequilibrium dissipation in living oocytes

(2016) É. Fodor et al.   EPL

Electric-field-stimulated protein mechanics

(2016) Doeke R. Hekstra et al.   NATURE

The role of protein dynamics in the evolution of new enzyme function

(2016) Eleanor Campbell et al.   Nature Chemical Biology

Equilibrium physics breakdown reveals the active nature of red blood cell flickering

(2016) H. Turlier et al.   Nature Physics

Strain analysis of protein structures and low dimensionality of mechanical allosteric couplings

(2016) Michael R. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broken detailed balance at mesoscopic scales in active biological systems

(2016) Christopher Battle et al.   SCIENCE

Perspectives on Electrostatics and Conformational Motions in Enzyme Catalysis

(2015) Philip Hanoian et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluctuations within Folded Proteins: Implications for Thermodynamic and Allosteric Regulation

(2015) Kateri H. DuBay et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enzyme Dynamics from NMR Spectroscopy

(2015) Arthur G. Palmer   ACCOUNTS OF CHEMICAL RESEARCH

Mapping the Dynamics Landscape of Conformational Transitions in Enzyme: The Adenylate Kinase Case

(2015) Dechang Li et al.   BIOPHYSICAL JOURNAL

Activity-driven fluctuations in living cells

(2015) É. Fodor et al.   EPL

Micromotors Powered by Enzyme Catalysis

(2015) Krishna K. Dey et al.   NANO LETTERS

The energy landscape of adenylate kinase during catalysis

(2015) S Jordan Kerns et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effective interactions in active Brownian suspensions

(2015) T. F. F. Farage et al.   PHYSICAL REVIEW E

Hydrodynamic collective effects of active protein machines in solution and lipid bilayers

(2015) Alexander S. Mikhailov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The energy landscape of adenylate kinase during catalysis

(2015) S Jordan Kerns et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Dynamical Nature of Enzymatic Catalysis

(2014) Robert Callender et al.   ACCOUNTS OF CHEMICAL RESEARCH

Keep on Moving: Discovering and Perturbing the Conformational Dynamics of Enzymes

(2014) Gira Bhabha et al.   ACCOUNTS OF CHEMICAL RESEARCH

Probing the Stochastic, Motor-Driven Properties of the Cytoplasm Using Force Spectrum Microscopy

(2014) Ming Guo et al.   CELL

The ensemble nature of allostery

(2014) Hesam N. Motlagh et al.   NATURE

The Ribosome as an Optimal Decoder: A Lesson in Molecular Recognition

(2013) Yonatan Savir et al.   CELL

Unraveling the role of protein dynamics in dihydrofolate reductase catalysis

(2013) L. Y. P. Luk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrodynamics of soft active matter

(2013) M. C. Marchetti et al.   REVIEWS OF MODERN PHYSICS

Taking Ockham's razor to enzyme dynamics and catalysis

(2012) David R. Glowacki et al.   Nature Chemistry

Transition Path Times for Nucleic Acid Folding Determined from Energy-Landscape Analysis of Single-Molecule Trajectories

(2012) Krishna Neupane et al.   PHYSICAL REVIEW LETTERS

A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis

(2011) G. Bhabha et al.   SCIENCE

Direct Observation of the Myosin Va Recovery Stroke That Contributes to Unidirectional Stepping along Actin

(2011) Katsuyuki Shiroguchi et al.   PLOS BIOLOGY

From “fluctuation fit” to “conformational selection”: Evolution, rediscovery, and integration of a concept

(2010) Beáta G. Vértessy et al.   BIOESSAYS

Enzyme dynamics point to stepwise conformational selection in catalysis

(2010) Buyong Ma et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Substrate Catalysis Enhances Single-Enzyme Diffusion

(2010) Hari S. Muddana et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RecA-Mediated Homology Search as a Nearly Optimal Signal Detection System

(2010) Yonatan Savir et al.   MOLECULAR CELL

Video imaging of walking myosin V by high-speed atomic force microscopy

(2010) Noriyuki Kodera et al.   NATURE

Tracing entire operation cycles of molecular motor hepatitis C virus helicase in structurally resolved dynamical simulations

(2010) H. Flechsig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overlap between folding and functional energy landscapes for adenylate kinase conformational change

(2010) Ulrika Olsson et al.   Nature Communications

A 21st century revisionist's view at a turning point in enzymology

(2009) Zachary D Nagel et al.   Nature Chemical Biology

At the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?

(2009) Shina C. L. Kamerlin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Free-Energy Landscape of Enzyme Catalysis†

(2008) Stephen J. Benkovic et al.   BIOCHEMISTRY

Folding and unfolding single RNA molecules under tension

(2008) Michael T Woodside et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Allosteric regulation and catalysis emerge via a common route

(2008) Nina M Goodey et al.   Nature Chemical Biology

Efficient coupling of catalysis and dynamics in the E1 component of Escherichia coli pyruvate dehydrogenase multienzyme complex

(2008) S. Kale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Observation of Hierarchical Folding in Single Riboswitch Aptamers

(2008) W. J. Greenleaf et al.   SCIENCE

Single-Molecule Measurement of the Stiffness of the Rigor Myosin Head

(2007) Alexandre Lewalle et al.   BIOPHYSICAL JOURNAL