Live or let die: Translational insights and clinical perspectives of gasdermin B‐dependent intestinal epithelial cell fate

Novel Insights Into the Interactions Between the Gut Microbiome, Inflammasomes, and Gasdermins During Colorectal Cancer

(2022) Giuseppe Privitera et al.   Frontiers in Cellular and Infection Microbiology

Pathogenic ubiquitination of GSDMB inhibits NK cell bactericidal functions

(2021) Justin M. Hansen et al.   CELL

Methotrexate and its mechanisms of action in inflammatory arthritis

(2020) Bruce N. Cronstein et al.   Nature Reviews Rheumatology

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

(2020) Deborah Nejman et al.   SCIENCE

Methotrexate is not superior to placebo in maintaining steroid-free response or remission in ulcerative colitis

(2018) Hans Herfarth et al.   GASTROENTEROLOGY

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis

(2018) Ronald A. Panganiban et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein

(2017) Kinlin L. Chao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methotrexate Is Not Superior to Placebo for Inducing Steroid-Free Remission, but Induces Steroid-Free Clinical Remission in a Larger Proportion of Patients With Ulcerative Colitis

(2016) Franck Carbonnel et al.   GASTROENTEROLOGY

Colorectal cancer

(2013) Hermann Brenner et al.   LANCET

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE