Targeted core-shell nanoparticles for precise CTCF gene insert in treatment of metastatic breast cancer

PGMD/curcumin nanoparticles for the treatment of breast cancer

(2021) Mankamna Kumari et al.   Scientific Reports

Breast cancer

(2021) Sibylle Loibl et al.   LANCET

Chitosan-Based Nanoparticles of Targeted Drug Delivery System in Breast Cancer Treatment

(2021) Yedi Herdiana et al.   Polymers

Update Breast Cancer 2020 Part 1 – Early Breast Cancer: Consolidation of Knowledge About Known Therapies

(2020) Andreas Schneeweiss et al.   GEBURTSHILFE UND FRAUENHEILKUNDE

Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin

(2020) Robert C. Klipp et al.   JOURNAL OF GENERAL PHYSIOLOGY

CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors

(2020) Dan Wang et al.   CELL

Reduction sensitive nanocarriers mPEG-g-γ-PGA/SSBPEI@siRNA for effective targeted delivery of survivin siRNA against NSCLC

(2020) Li Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapies

(2020) Antonio Marra et al.   npj Breast Cancer

Adeno-associated virus vector as a platform for gene therapy delivery

(2019) Dan Wang et al.   NATURE REVIEWS DRUG DISCOVERY

Breast Cancer Treatment

(2019) Adrienne G. Waks et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Treatment of Nonmetastatic Breast Cancer

(2019) Kathryn J. Ruddy et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genomic characterization of metastatic breast cancers

(2019) François Bertucci et al.   NATURE

Targeted Integration and High-Level Transgene Expression in AAVS1 Transgenic Mice after In Vivo HSC Transduction with HDAd5/35++ Vectors

(2019) Chang Li et al.   MOLECULAR THERAPY

Breast cancer

(2019) Nadia Harbeck et al.   Nature Reviews Disease Primers

Carboxylated branched poly(β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing

(2019) Yuan Rui et al.   Science Advances

Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites

(2018) Fan Xu et al.   BIOMATERIALS

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Engineering the Delivery System for CRISPR-Based Genome Editing

(2018) Zachary Glass et al.   TRENDS IN BIOTECHNOLOGY

Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

(2018) Bumwhee Lee et al.   Nature Biomedical Engineering

Progress in adjuvant systemic therapy for breast cancer

(2018) Noam F. Pondé et al.   Nature Reviews Clinical Oncology

Breast cancer

(2017) Nadia Harbeck et al.   LANCET

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Integrative clinical genomics of metastatic cancer

(2017) Dan R. Robinson et al.   NATURE

Treatment of low-risk ductal carcinoma in situ: is nothing better than something?

(2016) John R Benson et al.   LANCET ONCOLOGY

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

(2016) Serena Nik-Zainal et al.   NATURE

Enzymatic PEGylated Poly(lactone-co-β-amino ester) Nanoparticles as Biodegradable, Biocompatible and Stable Vectors for Gene Delivery

(2015) Ya Chen et al.   ACS Applied Materials & Interfaces

Quercetin conjugated poly(β-amino esters) nanogels for the treatment of cellular oxidative stress

(2015) Prachi Gupta et al.   Acta Biomaterialia

Proteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis

(2015) Matthew D. Dun et al.   MOLECULAR & CELLULAR PROTEOMICS

Therapeutic genome editing: prospects and challenges

(2015) David Benjamin Turitz Cox et al.   NATURE MEDICINE

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

(2015) C. E. Nelson et al.   SCIENCE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

(2014) Hao Yin et al.   NATURE BIOTECHNOLOGY

CTCF Haploinsufficiency Destabilizes DNA Methylation and Predisposes to Cancer

(2014) Christopher J. Kemp et al.   Cell Reports

Immune responses to AAV vectors: overcoming barriers to successful gene therapy

(2013) F. Mingozzi et al.   BLOOD

Breast cancer statistics, 2013

(2013) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mechanistic study of transfection of chitosan/DNA complexes coated by anionic poly(γ-glutamic acid)

(2012) Zi-Xian Liao et al.   BIOMATERIALS

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(γ-glutamic acid) complexes as a gene delivery vector

(2010) Shu-Fen Peng et al.   BIOMATERIALS

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Epigenetic Silencing of the p16INK4a Tumor Suppressor Is Associated with Loss of CTCF Binding and a Chromatin Boundary

(2009) Michael Witcher et al.   MOLECULAR CELL