Large Yellow Tea Extract Ameliorates Metabolic Syndrome by Suppressing Lipogenesis through SIRT6/SREBP1 Pathway and Modulating Microbiota in Leptin Receptor Knockout Rats

SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ

(2021) Danish Khan et al.   Cell Reports

SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP1

(2021) Chaoyu Zhu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Short-chain fatty acids as modulators of redox signaling in health and disease

(2021) Carmen González-Bosch et al.   Redox Biology

Chlorogenic Acid-Induced Gut Microbiota Improves Metabolic Endotoxemia

(2021) Xiaolin Ye et al.   Frontiers in Endocrinology

Role of gut microbiota in type 2 diabetes pathophysiology

(2020) Manoj Gurung et al.   EBioMedicine

DGAT1 inhibitors protect pancreatic β-cells from palmitic acid-induced apoptosis

(2020) Jun-shang Huang et al.   ACTA PHARMACOLOGICA SINICA

Sirt6 alleviated liver fibrosis by deacetylating conserved lysine 54 on Smad2 in hepatic stellate cells

(2020) Jinhang Zhang et al.   HEPATOLOGY

ERRγ suppression by Sirt6 alleviates cholestatic liver injury and fibrosis

(2020) Lihua Hao et al.   JCI Insight

Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism

(2020) Jin He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypoglycemic and Hypolipidemic Mechanism of Tea Polysaccharides on Type 2 Diabetic Rats via Gut Microbiota and Metabolism Alteration

(2020) Haishan Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

(2020) Giljae Lee et al.   Nature Communications

Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice

(2020) Ting-Ting Cai et al.   Frontiers in Pharmacology

A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease

(2019) Cyrielle Caussy et al.   Nature Communications

Green Tea Polyphenols Modify the Gut Microbiome in db/db Mice as Co-Abundance Groups Correlating with the Blood Glucose Lowering Effect

(2019) Tingting Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice

(2019) Hyeong Geug Kim et al.   JOURNAL OF HEPATOLOGY

Glycerol Monolaurate‐Mediated Attenuation of Metabolic Syndrome is Associated with the Modulation of Gut Microbiota in High Fat diet‐fed Mice

(2019) Minjie Zhao et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Biological fates of tea polyphenols and their interactions with microbiota in the gastrointestinal tract: implications on health effects

(2019) Tingting Chen et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis

(2019) In Hyuk Bang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

SIRT6, a Mammalian deacylase with multitasking abilities

(2019) Andrew R Chang et al.   PHYSIOLOGICAL REVIEWS

The Global Epidemic of the Metabolic Syndrome

(2018) Mohammad G. Saklayen   CURRENT HYPERTENSION REPORTS

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

(2018) N.H. Cho et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Gut commensalParabacteroides goldsteiniiplays a predominant role in the anti-obesity effects of polysaccharides isolated fromHirsutella sinensis

(2018) Tsung-Ru Wu et al.   GUT

Kudingcha and Fuzhuan Brick Tea Prevent Obesity and Modulate Gut Microbiota in High-Fat Diet Fed Mice

(2018) Guijie Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice

(2018) Yun Teng et al.   Nutrients

Green Tea Extract Protects Leptin-Deficient, Spontaneously Obese Mice from Hepatic Steatosis and Injury

(2018) Richard S. Bruno et al.   JOURNAL OF NUTRITION

Roasting improves the hypoglycemic effects of a large-leaf yellow tea infusion by enhancing the levels of epimerized catechins that inhibit α-glucosidase

(2018) Jie Zhou et al.   Food & Function

Preventive Effect of Flavonol Derivatives Abundant Sanglan Tea on Long-Term High-Fat-Diet-Induced Obesity Complications in C57BL/6 Mice

(2018) Ponmari Guruvaiah et al.   Nutrients

Tea Polysaccharides as Potential Therapeutic Options for Metabolic Diseases

(2018) Guijie Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Tea Polyphenols in Promotion of Human Health

(2018) Naghma Khan et al.   Nutrients

Decaffeinated green and black tea polyphenols decrease weight gain and alter microbiome populations and function in diet-induced obese mice

(2017) Susanne M. Henning et al.   EUROPEAN JOURNAL OF NUTRITION

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

(2017) Clair Crewe et al.   JOURNAL OF CLINICAL INVESTIGATION

Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice

(2017) Liufeng Wu et al.   Nature Communications

Anti-Obesity Effect of the Above-Ground Part of Valeriana dageletiana Nakai ex F. Maek Extract in High-Fat Diet-Induced Obese C57BL/6N Mice

(2017) Zhiqiang Wang et al.   Nutrients

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

(2016) Martin Kummen et al.   GUT

Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice

(2016) Giulio Marchesini et al.   HEPATOLOGY

Increased Systolic and Diastolic Blood Pressure Is Associated With Altered Gut Microbiota Composition and Butyrate Production in Early PregnancyNovelty and Significance

(2016) Luisa F. Gomez-Arango et al.   HYPERTENSION

A Polysaccharide from Ganoderma atrum Improves Liver Function in Type 2 Diabetic Rats via Antioxidant Action and Short-Chain Fatty Acids Excretion

(2016) Ke-Xue Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population

(2016) Carmen Haro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Comparative genomics and physiology of the butyrate-producing bacteriumIntestinimonas butyriciproducens

(2016) Thi Phuong Nam Bui et al.   Environmental Microbiology Reports

Safety and anti-hyperglycemic efficacy of various tea types in mice

(2016) Manman Han et al.   Scientific Reports

De novolipogenesis in the liver in health and disease: more than just a shunting yard for glucose

(2015) Francis W. B. Sanders et al.   BIOLOGICAL REVIEWS

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea

(2015) Chung S. Yang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Epigallocatechin Gallate: A Review of Its Beneficial Properties to Prevent Metabolic Syndrome

(2015) Samuel Legeay et al.   Nutrients

The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes

(2015) Marina Fugmann et al.   Scientific Reports

Preliminary Characterization of a Leptin Receptor Knockout Rat Created by CRISPR/Cas9 System

(2015) Dan Bao et al.   Scientific Reports

Xylo-oligosaccharides and virginiamycin differentially modulate gut microbial composition in chickens

(2015) Mohsen Pourabedin et al.   Microbiome

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice

(2014) Jingjing Wang et al.   ISME Journal

Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula

(2014) Jia Xu et al.   ISME Journal

Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation

(2014) Zhongwen Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes

(2013) Katherine R Amato et al.   ISME Journal

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Human intestinal microbiota composition is associated with local and systemic inflammation in obesity

(2013) Froukje J. Verdam et al.   Obesity

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Green tea powder and Lactobacillus plantarum affect gut microbiota, lipid metabolism and inflammation in high-fat fed C57BL/6J mice

(2012) Ulrika Axling et al.   Nutrition & Metabolism

Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients

(2012) Pawel Bogdanski et al.   NUTRITION RESEARCH

Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes

(2012) Chang Hwa Jung et al.   PHYTOTHERAPY RESEARCH

Identification of a cAMP-response Element in the Regulator of G-protein Signaling-2 (RGS2) Promoter as a Key Cis-regulatory Element for RGS2 Transcriptional Regulation by Angiotensin II in Cultured Vascular Smooth Muscles

(2011) Zhongwen Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The interaction of hepatic lipid and glucose metabolism in liver diseases

(2011) Lars P. Bechmann et al.   JOURNAL OF HEPATOLOGY

(−)−Epigallocatechin-3-gallate Inhibits Pancreatic Lipase and Reduces Body Weight Gain in High Fat-Fed Obese Mice

(2011) Kimberly A. Grove et al.   Obesity

Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women

(2010) A. Santacruz et al.   BRITISH JOURNAL OF NUTRITION

Dietary Green Tea Extract Lowers Plasma and Hepatic Triglycerides and Decreases the Expression of Sterol Regulatory Element-Binding Protein-1c mRNA and Its Responsive Genes in Fructose-Fed, Ovariectomized Rats

(2009) Sudeep Shrestha et al.   JOURNAL OF NUTRITION

Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet

(2009) Nora Chen et al.   NUTRITION RESEARCH

Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism

(2008) Yuguang Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE