Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis

A. Muciniphila Suppresses Colorectal Tumorigenesis by Inducing TLR2/NLRP3-Mediated M1-Like TAMs

(2021) Lina Fan et al.   Cancer Immunology Research

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fusobacterium nucleatum promotes colorectal cancer metastasis by modulating KRT7-AS/KRT7

(2020) Shujie Chen et al.   Gut Microbes

MiR‐129‐5p induces cell cycle arrest through modulating HOXC10/Cyclin D1 to inhibit gastric cancer progression

(2020) Jiamin He et al.   FASEB JOURNAL

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8+ T cells in mice

(2020) Lijuan Wang et al.   GUT

Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase

(2020) Qing Li et al.   GASTROENTEROLOGY

Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis

(2020) Liping Mao et al.   MATRIX BIOLOGY

F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer

(2020) Jie Hong et al.   GUT

KLF9 suppresses gastric cancer cell invasion and metastasis through transcriptional inhibition of MMP28

(2019) Yang Li et al.   FASEB JOURNAL

Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1

(2019) Mara Roxana Rubinstein et al.   EMBO REPORTS

EPB41L5 mediates TGF--induced metastasis of gastric cancer

(2019) Mi-Hyeon Jeong et al.   CLINICAL CANCER RESEARCH

ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori

(2019) Lennart Pfannkuch et al.   FASEB JOURNAL

RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1

(2018) Mengmeng Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B

(2018) Wei Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose

(2018) Ping Zhou et al.   NATURE

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

(2017) Yongzhi Yang et al.   GASTROENTEROLOGY

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

Tumour-derived Interleukin 35 promotes pancreatic ductal adenocarcinoma cell extravasation and metastasis by inducing ICAM1 expression

(2017) Chongbiao Huang et al.   Nature Communications

ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System

(2017) Stephanie Zimmermann et al.   Cell Reports

ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria

(2017) Milica Milivojevic et al.   PLoS Pathogens

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis

(2017) Saskia C. Stein et al.   PLoS Pathogens

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer

(2016) Qiaoyi Liang et al.   CLINICAL CANCER RESEARCH

Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis

(2015) Kosuke Mima et al.   GUT

Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity

(2015) R. G. Gaudet et al.   SCIENCE

Gastrointestinal Malignancy and the Microbiome

(2014) Maria T. Abreu et al.   GASTROENTEROLOGY

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Expression of Intercellular Adhesion Molecule 1 by Hepatocellular Carcinoma Stem Cells and Circulating Tumor Cells

(2013) Shupeng Liu et al.   GASTROENTEROLOGY

FilGAP, a Rho/Rho-associated protein kinase–regulated GTPase-activating protein for Rac, controls tumor cell migration

(2012) Koji Saito et al.   MOLECULAR BIOLOGY OF THE CELL

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

(2012) L J A C Hawinkels et al.   ONCOGENE

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

(2011) M. Castellarin et al.   GENOME RESEARCH

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

(2011) A. D. Kostic et al.   GENOME RESEARCH

Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition

(2011) Hua Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Adhesion Molecules: Role and Clinical Significance in Cancer

(2009) Nektaria Makrilia et al.   CANCER INVESTIGATION

The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis

(2009) Konstantinos A. Paschos et al.   CELLULAR SIGNALLING

Fusobacterium nucleatum Envelope Protein FomA Is Immunogenic and Binds to the Salivary Statherin-Derived Peptide

(2009) H. Nakagaki et al.   INFECTION AND IMMUNITY