Engineered nanogels simultaneously implement HDAC inhibition and chemotherapy to boost antitumor immunity via pyroptosis

Epigenetic modulation of immunotherapy and implications in head and neck cancer

(2021) Liye Zhou et al.   CANCER AND METASTASIS REVIEWS

Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer

(2021) Fang Sun et al.   Advanced Science

HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression

(2021) Xiaolei Li et al.   ONCOGENE

Acidity‐Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer

(2021) Rundi Song et al.   ADVANCED MATERIALS

A histone deacetylase inhibitor, panobinostat, enhances chimeric receptor antigen T cell anti-tumor effect against pancreatic cancer

(2021) Aesha I. Ali et al.   CLINICAL CANCER RESEARCH

Applying nanotechnology to boost cancer immunotherapy by promoting immunogenic cell death

(2021) Lvqin Fu et al.   CHINESE CHEMICAL LETTERS

Microenvironment‐Responsive Prodrug‐Induced Pyroptosis Boosts Cancer Immunotherapy

(2021) Yao Xiao et al.   Advanced Science

Engineering Stimuli‐Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy

(2020) Bo Hou et al.   ADVANCED MATERIALS

Tissue-resident memory T cells in breast cancer control and immunotherapy responses

(2020) Ann Byrne et al.   Nature Reviews Clinical Oncology

Immune checkpoint signaling and cancer immunotherapy

(2020) Xing He et al.   CELL RESEARCH

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

(2020) Zhibin Zhang et al.   NATURE

Memory T cells: strategies for optimizing tumor immunotherapy

(2020) Qingjun Liu et al.   Protein & Cell

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

(2020) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

Local and Targeted Delivery of Immune Checkpoint Blockade Therapeutics

(2020) Xiao Han et al.   ACCOUNTS OF CHEMICAL RESEARCH

Engineering immunogenic cell death with nanosized drug delivery systems improving cancer immunotherapy

(2020) Wenlu Yan et al.   CURRENT OPINION IN BIOTECHNOLOGY

Death by histone deacetylase inhibitor quisinostat in tongue squamous cell carcinoma via apoptosis, pyroptosis, and ferroptosis

(2020) Xinhuan Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tumor microenvironment-triggered MoS2@GA-Fe nanoreactor: A self-rolling enhanced chemodynamic therapy and hydrogen sulfide treatment for hepatocellular carcinoma

(2020) Huili Zheng et al.   CHEMICAL ENGINEERING JOURNAL

Bioresponsive prodrug nanogel-based polycondensate strategy deepens tumor penetration and potentiates oxidative stress

(2020) Xianbin Ma et al.   CHEMICAL ENGINEERING JOURNAL

Regulatory T cells in cancer immunosuppression — implications for anticancer therapy

(2019) Yosuke Togashi et al.   Nature Reviews Clinical Oncology

The emerging role of epigenetic therapeutics in immuno-oncology

(2019) Michael J. Topper et al.   Nature Reviews Clinical Oncology

DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation

(2019) Joel Zindel et al.   Annual Review of Pathology-Mechanisms of Disease

Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers

(2019) Jin-Xuan Fan et al.   NANO LETTERS

Combining epigenetic and immune therapy to overcome cancer resistance

(2019) Stephanie Gomez et al.   SEMINARS IN CANCER BIOLOGY

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Epigenetic modifiers as new immunomodulatory therapies in solid tumours

(2018) S Aspeslagh et al.   ANNALS OF ONCOLOGY

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies

(2018) Shetal A. Patel et al.   IMMUNITY

The function and dysfunction of memory CD8+ T cells in tumor immunity

(2018) James L. Reading et al.   IMMUNOLOGICAL REVIEWS

The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process

(2018) Antero Salminen et al.   AGEING RESEARCH REVIEWS

Immunogenic cell death in anticancer chemotherapy and its impact on clinical studies

(2018) Qiang Wang et al.   CANCER LETTERS

Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

(2018) Spencer C. Wei et al.   Cancer Discovery

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Regulatory T cells in cancer immunotherapy

(2016) Atsushi Tanaka et al.   CELL RESEARCH

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors

(2016) Jonathan M. Pitt et al.   IMMUNITY

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

(2016) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

(2015) Lorenzo Galluzzi et al.   CANCER CELL

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Class I histone deacetylase inhibition is a novel mechanism to target regulatory T cells in immunotherapy

(2012) Li Shen et al.   OncoImmunology

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

(2009) M. K. Srivastava et al.   CANCER RESEARCH

Histone Deacetylase Inhibitors in Cancer Therapy

(2009) Andrew A. Lane et al.   JOURNAL OF CLINICAL ONCOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY