Ocular Barriers and Their Influence on Gene Therapy Products Delivery
Published 2022 View Full Article
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Title
Ocular Barriers and Their Influence on Gene Therapy Products Delivery
Authors
Keywords
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Journal
Pharmaceutics
Volume 14, Issue 5, Pages 998
Publisher
MDPI AG
Online
2022-05-09
DOI
10.3390/pharmaceutics14050998
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Note: Only part of the references are listed.- Immune Privilege: The Microbiome and Uveitis
- (2021) Christine Mölzer et al. Frontiers in Immunology
- Gene therapy in the anterior eye segment
- (2021) Cynthia Amador et al. CURRENT GENE THERAPY
- Biodistribution of intravitreal lenadogene nolparvovec gene therapy in nonhuman primates
- (2021) David J. Calkins et al. Molecular Therapy-Methods & Clinical Development
- Delivery of Antisense Oligonucleotides to the Cornea
- (2020) Viet Q. Chau et al. Nucleic Acid Therapeutics
- Biological functions of tear film
- (2020) Stephen C. Pflugfelder et al. EXPERIMENTAL EYE RESEARCH
- Lactoferrin as potential preventative and adjunct treatment for COVID-19
- (2020) Raymond Chang et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Anatomie de la rétine
- (2020) Francine Behar-Cohen et al. M S-MEDECINE SCIENCES
- Characterization, Stability, and In Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in Ex Vivo Organotypic Retinal Explant Culture Models
- (2020) Jaakko Itkonen et al. Pharmaceutics
- Immune responses to retinal gene therapy using adeno-associated viral vectors – Implications for treatment success and safety
- (2020) Kirsten Bucher et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Changes in Collagen Structure and Permeability of Rat and Human Sclera After Crosslinking
- (2020) Peng Guo et al. Translational Vision Science & Technology
- Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration
- (2020) Karine Bigot et al. Pharmaceutics
- RNA therapeutics for retinal diseases
- (2020) Michael C Gemayel et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Adeno-Associated Viral Gene Therapy for Inherited Retinal Disease
- (2019) Tuyen Ong et al. PHARMACEUTICAL RESEARCH
- Ocular gene therapies in clinical practice: viral vectors and nonviral alternatives
- (2019) Thierry Bordet et al. DRUG DISCOVERY TODAY
- Penetration Enhancers in Ocular Drug Delivery
- (2019) Moiseev et al. Pharmaceutics
- Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat
- (2019) Mariana S. Dias et al. GENE THERAPY
- Retinal VEGFA maintains the ultrastructure and function of choriocapillaris by preserving the endothelial PLVAP
- (2019) Sang A. Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of retinal pigment epithelium permeability in drug transfer between posterior eye segment and systemic blood circulation
- (2019) Eva Ramsay et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Mucoadhesive dexamethasone-glycol chitosan nanoparticles for ophthalmic drug delivery
- (2019) Ailing Yu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The suprachoroidal space as a route of administration to the posterior segment of the eye
- (2018) Bryce Chiang et al. ADVANCED DRUG DELIVERY REVIEWS
- Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye
- (2018) Eva Ramsay et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Tivanisiran, a novel siRNA for the treatment of dry eye disease
- (2018) Javier Moreno-Montañés et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo
- (2018) Livia S. Carvalho et al. HUMAN GENE THERAPY
- Gene therapy and genome surgery in the retina
- (2018) James E. DiCarlo et al. JOURNAL OF CLINICAL INVESTIGATION
- Mechanisms of macular edema: Beyond the surface
- (2018) Alejandra Daruich et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Non-viral ocular gene therapy, pEYS606, for the treatment of non-infectious uveitis: Preclinical evaluation of the medicinal product
- (2018) Elodie Touchard et al. JOURNAL OF CONTROLLED RELEASE
- Pharmaceutical Development of AAV-Based Gene Therapy Products for the Eye
- (2018) Gerard A. Rodrigues et al. PHARMACEUTICAL RESEARCH
- Improved Intravitreal AAV-Mediated Inner Retinal Gene Transduction after Surgical Internal Limiting Membrane Peeling in Cynomolgus Monkeys
- (2017) Kazuhisa Takahashi et al. MOLECULAR THERAPY
- ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy
- (2017) Pierre-Raphaël Rothschild et al. Scientific Reports
- En Face Optical Coherence Tomography of Foveal Microstructure in Full-Thickness Macular Hole: A Model to Study Perifoveal Müller Cells
- (2015) Alexandre Matet et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Undefined role of mucus as a barrier in ocular drug delivery
- (2015) Marika Ruponen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Clinical staining of the ocular surface: Mechanisms and interpretations
- (2015) A.J. Bron et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Tight junction regulation through vesicle trafficking: bringing cells together
- (2014) Sarah J. Fletcher et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Long-term efficacy of ciliary muscle gene transfer of three sFlt-1 variants in a rat model of laser-induced choroidal neovascularization
- (2013) M El Sanharawi et al. GENE THERAPY
- Corneal Gene Therapy: Basic Science and Translational Perspective
- (2013) Rajiv R. Mohan et al. Ocular Surface
- Diffusion of macromolecules through sclera
- (2012) Heng Miao et al. ACTA OPHTHALMOLOGICA
- Intracellular mediators of JAM-A-dependent epithelial barrier function
- (2012) Ana C. Monteiro et al. Annals of the New York Academy of Sciences
- Suprachoroidal Electrotransfer: A Nonviral Gene Delivery Method to Transfect the Choroid and the Retina Without Detaching the Retina
- (2012) Elodie Touchard et al. MOLECULAR THERAPY
- Gene therapy in the Cornea: 2005–present
- (2011) Rajiv R. Mohan et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Macromolecular diffusion characteristics of ageing human Bruch's membrane: Implications for age-related macular degeneration (AMD)
- (2010) A.A. Hussain et al. EXPERIMENTAL EYE RESEARCH
- The ciliary smooth muscle electrotransfer: basic principles and potential for sustained intraocular production of therapeutic proteins
- (2010) Elodie Touchard et al. JOURNAL OF GENE MEDICINE
- Protein delivery for retinal diseases: From basic considerations to clinical applications
- (2010) M. El Sanharawi et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Amyloid-β(1-42) alters structure and function of retinal pigmented epithelial cells
- (2009) Julien Bruban et al. AGING CELL
- Changes in choriocapillaris fenestration of rat eyes after intravitreal bevacizumab injection
- (2009) Yukiko Shimomura et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction From the Vitreous
- (2009) Deniz Dalkara et al. MOLECULAR THERAPY
- Topische antiangiogene Therapie an der Hornhaut
- (2009) B. Regenfuss et al. OPHTHALMOLOGE
- The dynamic nature of Bruch's membrane
- (2009) J.C. Booij et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Role of lactoferrin in the tear film
- (2008) J FLANAGAN et al. BIOCHIMIE
- Immunohistochemical localisation of intravitreally injected bevacizumab at the posterior pole of the primate eye: implication for the treatment of retinal vein occlusion
- (2008) S Julien et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- PlGF-1 and VEGFR-1 Pathway Regulation of the External Epithelial Hemato-Ocular Barrier
- (2008) N. Miyamoto et al. OPHTHALMIC RESEARCH
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