Precision Oncology: Artificial Intelligence and DNA Methylation Analysis of Circulating Cell-Free DNA for Lung Cancer Detection

Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook

(2021) Evi Lianidou   Molecular Oncology

Artificial intelligence and leukocyte epigenomics: Evaluation and prediction of late-onset Alzheimer’s disease

(2021) Ray O. Bahado-Singh et al.   PLoS One

The Role of Liquid Biopsy in Early Diagnosis of Lung Cancer

(2021) Cláudia Freitas et al.   Frontiers in Oncology

How to use liquid biopsies to treat patients with cancer

(2021) L. De Mattos-Arruda et al.   ESMO Open

The US Preventive Services Task Force Recommendation on Lung Cancer Screening

(2021) Bryan S. Squires et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MiR-96-5p is an oncogene in lung adenocarcinoma and facilitates tumor progression through ARHGAP6 downregulation

(2021) Zhifang Liu et al.   JOURNAL OF APPLIED GENETICS

Permutation-based identification of important biomarkers for complex diseases via machine learning models

(2021) Xinlei Mi et al.   Nature Communications

Detection and characterization of lung cancer using cell-free DNA fragmentomes

(2021) Dimitrios Mathios et al.   Nature Communications

The complex interplay between DNA methylation and miRNAs in gene expression regulation

(2020) Andrea Fuso et al.   BIOCHIMIE

Integrative Analysis of Methylation and Gene Expression in Lung Adenocarcinoma and Squamous Cell Lung Carcinoma

(2020) Hao Zhang et al.   Frontiers in Bioengineering and Biotechnology

miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems

(2020) Fabian Kern et al.   NUCLEIC ACIDS RESEARCH

Restoration of miR‐330 expression suppresses lung cancer cell viability, proliferation, and migration

(2020) Ali Mohammadi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A novel circulating miRNA‐based signature for the early diagnosis and prognosis prediction of non–small‐cell lung cancer

(2020) Chengwei Zhou et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Plasma cell-free DNA methylation combined with tumor mutation detection in prognostic prediction of patients with non-small cell lung cancer (NSCLC)

(2020) Dan Guo et al.   MEDICINE

MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation

(2020) Xinyue Du et al.   Cancer Cell International

LncExpDB: an expression database of human long non-coding RNAs

(2020) Zhao Li et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Plasma Cell-Free DNA Methylation Profiling Identifies Potential Biomarkers for Lung Cancer

(2019) Wei Xu et al.   DISEASE MARKERS

MiR-141-3p functions as a tumor suppressor through directly targeting ZFR in non-small cell lung cancer

(2019) Weisong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

Epigenome-Wide Association Analysis of Differentially Methylated Signals in Blood Samples of Patients with Non-Small-Cell Lung Cancer

(2019) Yoonki Hong et al.   Journal of Clinical Medicine

Metabolomic identification of novel diagnostic biomarkers in ectopic pregnancy

(2019) Onur Turkoglu et al.   Metabolomics

MiR‐563 restrains cell proliferation via targeting LIN28B in human lung cancer

(2019) Xuefei Zhang et al.   Thoracic Cancer

Artificial intelligence in clinical and genomic diagnostics

(2019) Raquel Dias et al.   Genome Medicine

Artificial Intelligence and the detection of pediatric concussion using epigenomic analysis

(2019) Ray O. Bahado-Singh et al.   BRAIN RESEARCH

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MiR-2861 Behaves as a Biomarker of Lung Cancer Stem Cells and Regulates the HDAC5-ERK System Genes

(2018) Mengya Zhao et al.   Cellular Reprogramming

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

Blood Collection and Cell-Free DNA Isolation Methods Influence the Sensitivity of Liquid Biopsy Analysis for Colorectal Cancer Detection

(2018) Barbara Kinga Barták et al.   PATHOLOGY & ONCOLOGY RESEARCH

Roles of miR-200 family members in lung cancer: more than tumor suppressors

(2018) Cong Liu et al.   Future Oncology

MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

(2018) Mohammad Askandar Iqbal et al.   MOLECULAR ASPECTS OF MEDICINE

Clinical epigenetics: seizing opportunities for translation

(2018) María Berdasco et al.   NATURE REVIEWS GENETICS

The FDA Oncology Center of Excellence and precision medicine

(2017) Kirsten B Goldberg et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Deep Learning Accurately Predicts Estrogen Receptor Status in Breast Cancer Metabolomics Data

(2017) Fadhl M. Alakwaa et al.   JOURNAL OF PROTEOME RESEARCH

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

(2017) Kira S. Sheinerman et al.   Alzheimers Research & Therapy

MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway

(2016) Cheng-Cao Sun et al.   Aging-US

MicroRNA-663a is downregulated in non-small cell lung cancer and inhibits proliferation and invasion by targeting JunD

(2016) Yi Zhang et al.   BMC CANCER

Circulating exosomal microRNA-96 promotes cell proliferation, migration and drug resistance by targeting LMO7

(2016) Hao Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA-432 functions as a tumor suppressor gene through targeting E2F3 and AXL in lung adenocarcinoma

(2016) Ling Chen et al.   Oncotarget

CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter

(2016) Samrat Roy Choudhury et al.   Oncotarget

DNA methylation: conducting the orchestra from exposure to phenotype?

(2016) Fleur A. D. Leenen et al.   Clinical Epigenetics

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(2015) Anne-Sophie Jannot et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer

(2015) Xiangguang Shi et al.   Oncotarget

Building Predictive Models inRUsing thecaretPackage

(2015) Max Kuhn   Journal of Statistical Software

Genome-wide DNA Methylation Analysis of Lung Carcinoma Reveals One Neuroendocrine and Four Adenocarcinoma Epitypes Associated with Patient Outcome

(2014) A. Karlsson et al.   CLINICAL CANCER RESEARCH

Review of processing and analysis methods for DNA methylation array data

(2013) C S Wilhelm-Benartzi et al.   BRITISH JOURNAL OF CANCER

DNA Methylation of Transcriptional Enhancers and Cancer Predisposition

(2013) Dvir Aran et al.   CELL

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Upregulation of miR-136 in human non-small cell lung cancer cells promotes Erk1/2 activation by targeting PPP2R2A

(2013) Sining Shen et al.   TUMOR BIOLOGY

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer

(2011) Youwei Zhang et al.   CANCER LETTERS

An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA

(2011) S. Begum et al.   CLINICAL CANCER RESEARCH

Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer

(2011) Carina Roth et al.   Molecular Oncology

Epigenetic Regulation of miR-212 Expression in Lung Cancer

(2011) Mariarosaria Incoronato et al.   PLoS One

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Profiling of molecular pathways regulated by microRNA 601

(2009) Hiroaki Ohdaira et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY