Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook

Circulating breast-derived DNA allows universal detection and monitoring of localized breast cancer

(2020) J. Moss et al.   ANNALS OF ONCOLOGY

Epigenetic modulations and lineage plasticity in advanced prostate cancer

(2020) R. Ge et al.   ANNALS OF ONCOLOGY

Evaluating liquid biopsies for methylomic profiling of prostate cancer

(2020) Romina Silva et al.   Epigenetics

Parallel serial assessment of somatic mutation and methylation profile from circulating tumor DNA predicts treatment response and impending disease progression in osimertinib-treated lung adenocarcinoma patients

(2020) Shu Xia et al.   Translational Lung Cancer Research

Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

(2020) George D. Cresswell et al.   Nature Communications

Epigenetic Analysis of Circulating Tumor DNA in Localized and Metastatic Prostate Cancer: Evaluation of Clinical Biomarker Potential

(2020) Marianne Trier Bjerre et al.   Cells

Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

(2020) Pier Vitale Nuzzo et al.   NATURE MEDICINE

Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes

(2020) Farshad Nassiri et al.   NATURE MEDICINE

Development and initial clinical correlation of a DNA methylation‐based blood test for prostate cancer

(2020) Jacob J. K. Carson et al.   PROSTATE

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond

(2020) Laura Keller et al.   BRITISH JOURNAL OF CANCER

MGMT promoter methylation in triple negative breast cancer of the GeparSixto trial

(2020) Paul Jank et al.   PLoS One

Dynamics of the cell-free DNA methylome of metastatic prostate cancer during androgen-targeting treatment

(2020) Madonna R Peter et al.   Epigenomics

Advances in Prognostic Methylation Biomarkers for Prostate Cancer

(2020) Dilys Lam et al.   Cancers

Plasma-Based Longitudinal Evaluation of ESR1 Epigenetic Status in Hormone Receptor-Positive HER2-Negative Metastatic Breast Cancer

(2020) Lorenzo Gerratana et al.   Frontiers in Oncology

International liquid biopsy standardization alliance white paper

(2020) Dana Connors et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Discovery of novel DNA methylation biomarkers for non‐invasive sporadic breast cancer detection in the Latino population

(2020) Mónica Cappetta et al.   Molecular Oncology

KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer

(2020) Sofia Mastoraki et al.   Molecular Oncology

Circulating cell-free DNA in breast cancer: size profiling, levels, and methylation patterns lead to prognostic and predictive classifiers

(2019) Maria Panagopoulou et al.   ONCOGENE

The role of mSEPT9 in screening, diagnosis, and recurrence monitoring of colorectal cancer

(2019) Jie Sun et al.   BMC CANCER

Blood DNA methylation and breast cancer: A prospective case-cohort analysis in the Sister Study

(2019) Zongli Xu et al.   JNCI-Journal of the National Cancer Institute

Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies

(2019) Nunes et al.   Journal of Clinical Medicine

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

(2019) Lukas Vrba et al.   Epigenetics

Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection

(2019) Alessandro Leal et al.   CLINICAL CHEMISTRY

Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel

(2019) Vera Constâncio et al.   Clinical Epigenetics

A Diagnostic Panel of DNA Methylation Biomarkers for Lung Adenocarcinoma

(2019) Nan Shen et al.   Frontiers in Oncology

Epigenomic and Transcriptomic Characterization of Secondary Breast Cancers

(2018) Amanda N. Graff-Baker et al.   ANNALS OF SURGICAL ONCOLOGY

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

(2018) Katherine A. Hoadley et al.   CELL

Cell-Free DNA Modification Dynamics in Abiraterone Acetate-Treated Prostate Cancer Patients

(2018) Juozas Gordevičius et al.   CLINICAL CANCER RESEARCH

Evaluation of Preanalytical Conditions and Implementation of Quality Control Steps for Reliable Gene Expression and DNA Methylation Analyses in Liquid Biopsies

(2018) Martha Zavridou et al.   CLINICAL CHEMISTRY

Mutation and Methylation Analysis of Circulating Tumor DNA Can Be Used for Follow-up of Metastatic Colorectal Cancer Patients

(2018) Nele Boeckx et al.   Clinical Colorectal Cancer

Review of Blood-Based Colorectal Cancer Screening: How Far Are Circulating Cell-Free DNA Methylation Markers From Clinical Implementation?

(2018) Mai-Britt Worm Ørntoft   Clinical Colorectal Cancer

Biomarker potential of ST6GALNAC3 and ZNF660 promoter hypermethylation in prostate cancer tissue and liquid biopsies

(2018) Christa Haldrup et al.   Molecular Oncology

DNA methylation-based classification of central nervous system tumours

(2018) David Capper et al.   NATURE

Epigenome-based cancer risk prediction: rationale, opportunities and challenges

(2018) Martin Widschwendter et al.   Nature Reviews Clinical Oncology

Analysis of DNA methylation in cancer: location revisited

(2018) Alexander Koch et al.   Nature Reviews Clinical Oncology

Blood Collection and Cell-Free DNA Isolation Methods Influence the Sensitivity of Liquid Biopsy Analysis for Colorectal Cancer Detection

(2018) Barbara Kinga Barták et al.   PATHOLOGY & ONCOLOGY RESEARCH

Epigenetic markers in circulating cell-free DNA as prognostic markers for survival of castration-resistant prostate cancer patients

(2018) Rianne J. Hendriks et al.   PROSTATE

A five-CpG DNA methylation score to predict metastatic-lethal outcomes in men treated with radical prostatectomy for localized prostate cancer

(2018) Shanshan Zhao et al.   PROSTATE

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

(2018) Christopher J. Ricketts et al.   Cell Reports

A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples

(2018) María Gallardo-Gómez et al.   Clinical Epigenetics

Circulating tumour DNA for monitoring colorectal cancer—a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection

(2018) Erin L. Symonds et al.   Clinical Epigenetics

Principles of DNA methylation and their implications for biology and medicine

(2018) Yuval Dor et al.   LANCET

Liquid Biopsies

(2018) Evi Lianidou et al.   GENES CHROMOSOMES & CANCER

Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target

(2018) Chin-Sheng Hung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

(2018) Shu Yi Shen et al.   NATURE

Clinical epigenetics: seizing opportunities for translation

(2018) María Berdasco et al.   NATURE REVIEWS GENETICS

Application of Cell-free DNA Analysis to Cancer Treatment

(2018) Ryan B. Corcoran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic profiling for the molecular classification of metastatic brain tumors

(2018) Javier I. J. Orozco et al.   Nature Communications

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

(2018) Joshua Moss et al.   Nature Communications

A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA

(2018) Sofia Salta et al.   Journal of Clinical Medicine

Cell-Free DNA as a Diagnostic Blood-Based Biomarker for Colorectal Cancer: A Systematic Review

(2018) Joel Petit et al.   JOURNAL OF SURGICAL RESEARCH

Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer

(2017) Ludovic Barault et al.   GUT

Detection of Methylated Circulating DNA as Noninvasive Biomarkers for Breast Cancer Diagnosis

(2017) Isabella Wai Yin Cheuk et al.   Journal of Breast Cancer

Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study

(2017) Kala Visvanathan et al.   JOURNAL OF CLINICAL ONCOLOGY

Epi proColon® 2.0 CE: A Blood-Based Screening Test for Colorectal Cancer

(2017) Yvette N. Lamb et al.   Molecular Diagnosis & Therapy

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

(2017) Christopher Abbosh et al.   NATURE

Lung cancer epigenetics: From knowledge to applications

(2017) Michaël Duruisseaux et al.   SEMINARS IN CANCER BIOLOGY

Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients

(2017) Mariana Brait et al.   Oncotarget

SOX17 promoter methylation in plasma circulating tumor DNA of patients with non-small cell lung cancer

(2016) Ioanna Balgkouranidou et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

(2016) Sebastian Moran et al.   LANCET ONCOLOGY

Gene expression profiling and DNA methylation analyses of CTCs

(2016) Evi S. Lianidou   Molecular Oncology

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy

(2016) C. Alix-Panabieres et al.   Cancer Discovery

Digital PCR quantification ofMGMTmethylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer

(2015) L. Barault et al.   ANNALS OF ONCOLOGY

Detection and Dynamic Changes of EGFR Mutations from Circulating Tumor DNA as a Predictor of Survival Outcomes in NSCLC Patients Treated with First-line Intercalated Erlotinib and Chemotherapy

(2015) T. Mok et al.   CLINICAL CANCER RESEARCH

Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer

(2014) I Balgkouranidou et al.   BRITISH JOURNAL OF CANCER

Lung cancer epigenetics: emerging biomarkers

(2013) Ioanna Balgkouranidou et al.   Biomarkers in Medicine

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis

(2013) Diego M. Marzese et al.   HUMAN MOLECULAR GENETICS

SOX17 Promoter Methylation in Circulating Tumor Cells and Matched Cell-Free DNA Isolated from Plasma of Patients with Breast Cancer

(2012) M. Chimonidou et al.   CLINICAL CHEMISTRY