Endolysosome Iron Chelation Inhibits HIV-1 Protein-Induced Endolysosome De-Acidification-Induced Increases in Mitochondrial Fragmentation, Mitophagy, and Cell Death

Heterogeneity of ferrous iron‐containing endolysosomes and effects of endolysosome iron on endolysosome numbers, sizes, and localization patterns

(2022) Peter W. Halcrow et al.   JOURNAL OF NEUROCHEMISTRY

HIV-1 gp120-Induced Endolysosome de-Acidification Leads to Efflux of Endolysosome Iron, and Increases in Mitochondrial Iron and Reactive Oxygen Species

(2021) Peter W. Halcrow et al.   Journal of Neuroimmune Pharmacology

Role of endolysosome function in iron metabolism and brain carcinogenesis

(2021) Peter W. Halcrow et al.   SEMINARS IN CANCER BIOLOGY

The lysosome as a master regulator of iron metabolism

(2021) Francesca Rizzollo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endolysosome iron restricts Tat-mediated HIV-1 LTR transactivation by increasing HIV-1 Tat oligomerization and β-catenin expression

(2021) Nabab Khan et al.   JOURNAL OF NEUROVIROLOGY

Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

(2020) Ross A. Weber et al.   MOLECULAR CELL

Autophagy in Human Diseases

(2020) Noboru Mizushima et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exposure to Morphine and Caffeine Induces Apoptosis and Mitochondrial Dysfunction in a Neonatal Rat Brain

(2020) Sweatha Kasala et al.   Frontiers in Pediatrics

The Prevalence of Frascati-Criteria-Based HIV-Associated Neurocognitive Disorder (HAND) in HIV-Infected Adults: A Systematic Review and Meta-Analysis

(2020) Jiaqi Wei et al.   Frontiers in Neurology

Lysosomal size matters

(2019) Mariana E. G. Araujo et al.   TRAFFIC

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

(2018) Rawan El-Amine et al.   Redox Biology

Human Immunodeficiency Virus Type-1 gp120 and Tat Induce Mitochondrial Fragmentation and Incomplete Mitophagy in Human Neurons

(2018) Carmen Teodorof-Diedrich et al.   JOURNAL OF VIROLOGY

Accumulation of autophagosomes confers cytotoxicity

(2017) Robert W. Button et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disorders of lysosomal acidification—The emerging role of v-ATPase in aging and neurodegenerative disease

(2016) Daniel J. Colacurcio et al.   AGEING RESEARCH REVIEWS

The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7

(2016) Ibraheem Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 gp120 induces type-1 programmed cell death through ER stress employing IRE1α, JNK and AP-1 pathway

(2016) Ankit Shah et al.   Scientific Reports

Lysosomal Physiology

(2015) Haoxing Xu et al.   Annual Review of Physiology

HIV-1 gp120 and morphine induced oxidative stress: role in cell cycle regulation

(2015) Thangavel Samikkannu et al.   Frontiers in Microbiology

HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse

(2014) Nazira El-Hage et al.   JOURNAL OF VIROLOGY

Suppression of Lysosome Function Induces Autophagy via a Feedback Down-regulation of MTOR Complex 1 (MTORC1) Activity

(2013) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment

(2013) S. Spudich et al.   Cold Spring Harbor Perspectives in Medicine

Role of Endolysosomes in HIV-1 Tat-Induced Neurotoxicity

(2012) Liang Hui et al.   ASN Neuro

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

How Much Gp120 Is There?

(2010) Nathan W. Cummins et al.   JOURNAL OF INFECTIOUS DISEASES

Pathophysiology of neuropathic lysosomal storage disorders

(2010) Cinzia Maria Bellettato et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Review: Autophagy and neurodegeneration: survival at a cost?

(2010) S. J. Cherra III et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE