Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression ofSLC1A3andEPHB2

Stimulation of EphB2/ephrin-B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells

(2015) Lifang Zhu et al.   CELL PROLIFERATION

Activation Of Nfatc2 in osteoblasts causes osteopenia

(2015) Stefano Zanotti et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

(2015) Hou‐Feng Zheng et al.   NATURE

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci

(2015) Sjur Reppe et al.   PLoS One

Methods and reliability of radiographic vertebral fracture detection in older men: The osteoporotic fractures in men study

(2014) Peggy M. Cawthon et al.   BONE

Ephrin B2/EphB4 Mediates the Actions of IGF-I Signaling in Regulating Endochondral Bone Formation

(2014) Yongmei Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB

(2014) Bo Yu et al.   NATURE MEDICINE

Pou3f4-Mediated Regulation of Ephrin-B2 Controls Temporal Bone Development in the Mouse

(2014) Steven Raft et al.   PLoS One

Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture

(2013) J. Brent Richards   ANNALS OF INTERNAL MEDICINE

Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus

(2013) Ling Oei et al.   BONE

Trends in Fracture Incidence: A Population-Based Study Over 20 Years

(2013) Shreyasee Amin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

The associations between QCT-based vertebral bone measurements and prevalent vertebral fractures depend on the spinal locations of both bone measurement and fracture

(2013) D. E. Anderson et al.   OSTEOPOROSIS INTERNATIONAL

Comparison of QCT and DXA: Osteoporosis Detection Rates in Postmenopausal Women

(2013) Na Li et al.   International Journal of Endocrinology

Genetic Determinants of Trabecular and Cortical Volumetric Bone Mineral Densities and Bone Microstructure

(2013) Lavinia Paternoster et al.   PLoS Genetics

Failure strength of human vertebrae: Prediction using bone mineral density measured by DXA and bone volume by micro-CT

(2012) Egon Perilli et al.   BONE

BMP2 Differentially Regulates the Expression of Gremlin1 and Gremlin2, the Negative Regulators of BMP Function, During Osteoblast Differentiation

(2012) Dai Suzuki et al.   CALCIFIED TISSUE INTERNATIONAL

Altered Phenotype of the Vestibular Organ in GLAST-1 Null Mice

(2012) Sebastian P. Schraven et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

EphrinB2/EphB4 inhibition in the osteoblast lineage modifies the anabolic response to parathyroid hormone

(2012) Farzin M Takyar et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Genetics of osteoporosis from genome-wide association studies: advances and challenges

(2012) J. Brent Richards et al.   NATURE REVIEWS GENETICS

Emergency department visits due to vertebral fractures in the Netherlands, 1986–2008: Steep increase in the oldest old, strong association with falls

(2011) Christian Oudshoorn et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

QCT measures of bone strength at the thoracic and lumbar spine: The Framingham study

(2011) Elizabeth J Samelson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the framingham study

(2011) Ching-Ti Liu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Serum IGF-1 Affects Skeletal Acquisition in a Temporal and Compartment-Specific Manner

(2011) Hayden-William Courtland et al.   PLoS One

Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk

(2011) Emma L. Duncan et al.   PLoS Genetics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The downstream effects of vitamin D in spermatozoa needs further study

(2010) B. Yang et al.   HUMAN REPRODUCTION

Comparison of methods for defining prevalent vertebral deformities: The study of osteoporotic fractures

(2010) Dennis M. Black et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A new approach to defining normal vertebral dimensions

(2010) Dennis M. Black et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Vertebral fracture assessment using a semiquantitative technique

(2010) Harry K. Genant et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map

(2010) Cheryl L Ackert-Bicknell et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men

(2010) J. M. Zmuda et al.   OSTEOPOROSIS INTERNATIONAL

Secular decreases in fracture rates 1986–2006 for Manitoba, Canada: a population-based analysis

(2010) W. D. Leslie et al.   OSTEOPOROSIS INTERNATIONAL

Measurement of Thoracic Bone Mineral Density with Quantitative CT

(2010) Matthew J. Budoff et al.   RADIOLOGY

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits

(2010) Yi-Hsiang Hsu et al.   PLoS Genetics

Eight genes are highly associated with BMD variation in postmenopausal Caucasian women

(2009) Sjur Reppe et al.   BONE

Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro

(2008) Hisashi Ideno et al.   EXPERIMENTAL CELL RESEARCH

Multiple Genetic Loci for Bone Mineral Density and Fractures

(2008) Unnur Styrkarsdottir et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bone microstructure and its associated genetic variability in 12 inbred mouse strains: μCT study and in silico genome scan

(2007) Ilya Sabsovich et al.   BONE