Mesoporous Silica-Based Nanoparticles as Non-Viral Gene Delivery Platform for Treating Retinitis Pigmentosa

Osteogenic silver oxide doped mesoporous bioactive glass for controlled release of doxorubicin against bone cancer cell line (MG-63): In vitro and in vivo cytotoxicity evaluation

(2020) Muhammad Saif ur Rahman et al.   CERAMICS INTERNATIONAL

Silica-Based Nanoparticles for Biomedical Applications: From Nanocarriers to Biomodulators

(2020) Yannan Yang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cloaking Silica Nanoparticles with Functional Protein Coatings for Reduced Complement Activation and Cellular Uptake

(2020) Jae Hyeon Park et al.   ACS Nano

Immune responses to retinal gene therapy using adeno-associated viral vectors – Implications for treatment success and safety

(2020) Kirsten Bucher et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Current Clinical Applications of In Vivo Gene Therapy with AAVs

(2020) Jerry R. Mendell et al.   MOLECULAR THERAPY

Emerging Trends in Nanomedicine for Improving Ocular Drug Delivery: Light-Responsive Nanoparticles, Mesoporous Silica Nanoparticles, and Contact Lenses

(2020) Flávia S. C. Rodrigues et al.   ACS Biomaterials-Science & Engineering

In Vitro Gene Delivery in Retinal Pigment Epithelium Cells by Plasmid DNA-Wrapped Gold Nanoparticles

(2019) Trigueros et al.   Genes

Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins

(2019) Lourdes Valdés-Sánchez et al.   MOLECULAR MEDICINE

AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE Cells

(2019) Elizabeth M. Brydon et al.   Molecular Therapy-Methods & Clinical Development

Non-syndromic retinitis pigmentosa

(2018) Sanne K. Verbakel et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Folic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers

(2018) Wei Qu et al.   International Journal of Nanomedicine

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa

(2018) Adriana Buskin et al.   Nature Communications

Local Delivery and Sustained-Release of Nitric Oxide Donor Loaded in Mesoporous Silica Particles for Efficient Treatment of Primary Open-Angle Glaucoma

(2018) Chunchun Hu et al.   Advanced Healthcare Materials

A novel penetratin-modified complex for noninvasive intraocular delivery of antisense oligonucleotides

(2017) Lingyu Tai et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

EpCAM antibody-conjugated mesoporous silica nanoparticles to enhance the anticancer efficacy of carboplatin in retinoblastoma

(2017) Wei Qu et al.   Materials Science & Engineering C-Materials for Biological Applications

Mesoporous nano-bioglass designed for the release of imatinib and in vitro inhibitory effects on cancer cells

(2017) Muhammad Shoaib et al.   Materials Science & Engineering C-Materials for Biological Applications

Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights

(2017) María Vallet-Regí et al.   MOLECULES

Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

(2017) Wenzhang Cha et al.   MOLECULES

Gelatin-functionalized mesoporous silica nanoparticles with sustained release properties for intracameral pharmacotherapy of glaucoma

(2017) Yu-Te Liao et al.   Journal of Materials Chemistry B

Dual delivery of siRNA and plasmid DNA using mesoporous silica nanoparticles to differentiate induced pluripotent stem cells into dopaminergic neurons

(2017) Jen-Hsuan Chang et al.   Journal of Materials Chemistry B

Inhibition of osteoclastogenesis through siRNA delivery with tunable mesoporous bioactive nanocarriers

(2016) Tae-Hyun Kim et al.   Acta Biomaterialia

Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles

(2016) P.S. Apaolaza et al.   BIOMATERIALS

In vitro stimulation of MC3T3-E1cells and sustained drug delivery by a hierarchical nanostructured SiO2CaOP2O5 scaffold

(2016) M. Lourdes Ramiro-Gutiérrez et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Span poly-L-arginine nanoparticles are efficient non-viral vectors for PRPF31 gene delivery: An approach of gene therapy to treat retinitis pigmentosa

(2016) Andrea Pensado et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mutations in spliceosomal proteins and retina degeneration

(2016) Šárka Růžičková et al.   RNA Biology

Effect of Aminated Mesoporous Bioactive Glass Nanoparticles on the Differentiation of Dental Pulp Stem Cells

(2016) Jung-Hwan Lee et al.   PLoS One

Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure

(2015) B Greenberg et al.   GENE THERAPY

Non-viral therapeutic approaches to ocular diseases: An overview and future directions

(2015) Rahel Zulliger et al.   JOURNAL OF CONTROLLED RELEASE

A facile synthesis of novel mesoporous bioactive glass nanoparticles with various morphologies and tunable mesostructure by sacrificial liquid template method

(2015) Qiming Liang et al.   MATERIALS LETTERS

Mutations in Pre-mRNA Processing Factors 3, 8, and 31 Cause Dysfunction of the Retinal Pigment Epithelium

(2014) Michael H. Farkas et al.   AMERICAN JOURNAL OF PATHOLOGY

Nonviral Cell Labeling and Differentiation Agent for Induced Pluripotent Stem Cells Based on Mesoporous Silica Nanoparticles

(2013) Wei Chen et al.   ACS Nano

Collagen hydrogels incorporated with surface-aminated mesoporous nanobioactive glass: Improvement of physicochemical stability and mechanical properties is effective for hard tissue engineering

(2013) Ahmed El-Fiqi et al.   Acta Biomaterialia

Alternative splicing and retinal degeneration

(2013) M M Liu et al.   CLINICAL GENETICS

Persistence of non-viral vector mediated RPE65 expression: Case for viability as a gene transfer therapy for RPE-based diseases

(2013) Adarsha Koirala et al.   JOURNAL OF CONTROLLED RELEASE

Nanoporous silica microparticle interaction with toll-like receptor agonists in macrophages

(2012) M. Cejudo-Guillén et al.   Acta Biomaterialia

Facile Synthesis of Monodispersed Mesoporous Silica Nanoparticles with Ultralarge Pores and Their Application in Gene Delivery

(2011) Mi-Hee Kim et al.   ACS Nano

Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals

(2010) Jie Lu et al.   Small

Structural study of sol–gel silicate glasses by IR and Raman spectroscopies

(2009) H. Aguiar et al.   JOURNAL OF NON-CRYSTALLINE SOLIDS

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE