New diagnostic and therapeutic strategies for myocardial infarction via nanomaterials

CAR T cells produced in vivo to treat cardiac injury

(2022) Joel G. Rurik et al.   SCIENCE

Cardiac macrophages regulate isoproterenol-induced Takotsubo-like cardiomyopathy

(2022) Xudong Liao et al.   JCI Insight

Hybrid Nanosystems for Biomedical Applications

(2021) Joshua Seaberg et al.   ACS Nano

Dimethyl Itaconate‐Loaded Nanofibers Rewrite Macrophage Polarization, Reduce Inflammation, and Enhance Repair of Myocardic Infarction

(2021) Jayachandra Reddy Nakkala et al.   Small

Highly Efficient MicroRNA Delivery Using Functionalized Carbon Dots for Enhanced Conversion of Fibroblasts to Cardiomyocytes

(2021) Lei Yang et al.   International Journal of Nanomedicine

Nanoparticle‐Mediated Blocking of Excessive Inflammation for Prevention of Heart Failure Following Myocardial Infarction

(2021) Sung Pil Kwon et al.   Small

Nanoparticle‐Mediated Simultaneous Targeting of Mitochondrial Injury and Inflammation Attenuates Myocardial Ischemia‐Reperfusion Injury

(2021) Gentaro Ikeda et al.   Journal of the American Heart Association

Nanoparticles to Target and Treat Macrophages: The Ockham’s Concept?

(2021) Mireia Medrano-Bosch et al.   Pharmaceutics

Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution

(2021) Lili Bao et al.   Bioactive Materials

Near Complete Repair After Myocardial Infarction in Adult Mice by Altering the Inflammatory Response With Intramyocardial Injection of α-Gal Nanoparticles

(2021) Uri Galili et al.   Frontiers in Cardiovascular Medicine

Polymer nano-systems for the encapsulation and delivery of active biomacromolecular therapeutic agents

(2021) Marina Machtakova et al.   CHEMICAL SOCIETY REVIEWS

Acute myocardial infarction in young patients

(2021) Wojciech Zasada et al.   Kardiologia Polska

Correction to: Hydrogel-load exosomes derived from dendritic cells improve cardiac function via Treg cells and the polarization of macrophages following myocardial infarction

(2021) Youming Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

(2021) Tianjiao Zhao et al.   Bioactive Materials

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Role of microRNAs in Venous Thromboembolism

(2020) Vânia M. Morelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Attenuation of cadmium-induced vascular toxicity by pro-angiogenic nanorods

(2020) Arpita Roy et al.   Materials Science & Engineering C-Materials for Biological Applications

A Novel Anti‐Coagulative Nanocomplex in Delivering miRNA‐1 Inhibitor Against Microvascular Obstruction of Myocardial Infarction

(2020) Ting Hong et al.   Advanced Healthcare Materials

Injectable Hydrogel-Based Nanocomposites for Cardiovascular Diseases

(2020) Xiaoshan Liao et al.   Frontiers in Bioengineering and Biotechnology

High-Efficiency CNNS@NH2-MIL(Fe) Electrochemiluminescence Emitters Coupled with Ti3C2 Nanosheets as a Matrix for a Highly Sensitive Cardiac Troponin I Assay

(2020) Xinya Jiang et al.   ANALYTICAL CHEMISTRY

Nose-to-brain drug delivery mediated by polymeric nanoparticles: influence of PEG surface coating

(2020) Edilson Ribeiro de Oliveira Junior et al.   Drug Delivery and Translational Research

Angiogenesis After Acute Myocardial Infarction

(2020) Xuekun Wu et al.   CARDIOVASCULAR RESEARCH

Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction

(2020) Laura Alonso-Herranz et al.   eLife

Macrophages in Cardiovascular Homeostasis and Disease

(2019) Dian J. Cao   CIRCULATION

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia–reperfusion injury by inhibiting monocyte-mediated inflammation in mice

(2019) Masaki Fujiwara et al.   CARDIOVASCULAR RESEARCH

A polymeric micelle with an endosomal pH-sensitivity for intracellular delivery and enhanced antitumor efficacy of hydroxycamptothecin

(2019) Xiaohui Pu et al.   Acta Biomaterialia

Surface tethering of stem cells with H2O2-responsive anti-oxidizing colloidal particles for protection against oxidation-induced death

(2019) Jye Yng Teo et al.   BIOMATERIALS

Facile and clean synthesis of dihydroxylatopillar[5]arene-stabilized gold nanoparticles integrated Pd/MnO2 nanocomposites for robust and ultrasensitive detection of cardiac troponin I

(2019) Xingcan Qian et al.   BIOSENSORS & BIOELECTRONICS

An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium

(2019) Huaxiao Yang et al.   ACS Nano

2D Nanomaterials for Cancer Theranostic Applications

(2019) Liang Cheng et al.   ADVANCED MATERIALS

The question of toxicity of nanomaterials and nanoparticles

(2019) Christine Allen   JOURNAL OF CONTROLLED RELEASE

Myocardial‐Infarction‐Responsive Smart Hydrogels Targeting Matrix Metalloproteinase for On‐Demand Growth Factor Delivery

(2019) Caixia Fan et al.   ADVANCED MATERIALS

Spatiotemporal delivery of basic fibroblast growth factor to directly and simultaneously attenuate cardiac fibrosis and promote cardiac tissue vascularization following myocardial infarction

(2019) Zhaobo Fan et al.   JOURNAL OF CONTROLLED RELEASE

Injectable Citrate-Based Hydrogel as an Angiogenic Biomaterial Improves Cardiac Repair after Myocardial Infarction

(2019) Zhize Yuan et al.   ACS Applied Materials & Interfaces

Nanotechnology in regenerative ophthalmology

(2019) Fitsum Feleke Sahle et al.   ADVANCED DRUG DELIVERY REVIEWS

Metabolic regulation of gene expression by histone lactylation

(2019) Di Zhang et al.   NATURE

Development of a nanomedicine-loaded hydrogel for sustained delivery of an angiogenic growth factor to the ischaemic myocardium

(2019) Joanne O’Dwyer et al.   Drug Delivery and Translational Research

Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic

(2018) Emily Mihalko et al.   ACS Nano

Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing

(2018) Mirza Ali Mofazzal Jahromi et al.   ADVANCED DRUG DELIVERY REVIEWS

Unlockable Nanocomplexes with Self-Accelerating Nucleic Acid Release for Effective Staged Gene Therapy of Cardiovascular Diseases

(2018) Jing-Jun Nie et al.   ADVANCED MATERIALS

Copper Transporters and Copper Chaperones: Roles in Cardiovascular Physiology and Disease.

(2018) Tohru Fukai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Fluorescent Nanoprobes with Oriented Modified Antibodies to Improve Lateral Flow Immunoassay of Cardiac Troponin I

(2018) Doudou Lou et al.   ANALYTICAL CHEMISTRY

Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing

(2018) Hang Lin et al.   BIOMATERIALS

Novel angiogenesis therapeutics by redox injectable hydrogel - Regulation of local nitric oxide generation for effective cardiovascular therapy

(2018) Long Binh Vong et al.   BIOMATERIALS

Engineered cardiac tissue patch maintains structural and electrical properties after epicardial implantation

(2018) Christopher P. Jackman et al.   BIOMATERIALS

Nucleic acid aptamer-based methods for diagnosis of infections

(2018) Ki Soo Park   BIOSENSORS & BIOELECTRONICS

Cytosolic DNA Sensing Promotes Macrophage Transformation and Governs Myocardial Ischemic Injury

(2018) Dian J. Cao et al.   CIRCULATION

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency

(2018) Aida Rodríguez‐Nuevo et al.   EMBO JOURNAL

Competitive Multiple-Mechanism-Driven Electrochemiluminescent Detection of 8-Hydroxy-2′-deoxyguanosine

(2018) Yanqin Lv et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exercise preconditioning and low dose copper nanoparticles exhibits cardioprotection through targeting GSK-3β phosphorylation in ischemia/reperfusion induced myocardial infarction

(2018) Arun K. Sharma et al.   MICROVASCULAR RESEARCH

The human heart contains distinct macrophage subsets with divergent origins and functions

(2018) Geetika Bajpai et al.   NATURE MEDICINE

Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models

(2018) Masaki Tokutome et al.   CARDIOVASCULAR RESEARCH

Preparation of Micro/Nano-Structure Copper-Substituted Hydroxyapatite Scaffolds with Improved Angiogenesis Capacity for Bone Regeneration

(2018) Adil Elrayah et al.   Materials

NIPAM-based Microgel Microenvironment Regulates the Therapeutic Function of Cardiac Stromal Cells

(2018) Xiaolin Cui et al.   ACS Applied Materials & Interfaces

Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells

(2018) Shengcai Qi et al.   Small

Simple, low-cost, sensitive and label-free aptasensor for the detection of cardiac troponin I based on a gold nanoparticles modified titanium foil

(2018) Nasrin Siraj Lopa et al.   BIOSENSORS & BIOELECTRONICS

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

Recent progress in electrochemical sensing of cardiac troponin by using nanomaterial-induced signal amplification

(2017) Qinglin Sheng et al.   MICROCHIMICA ACTA

Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome

(2017) Junnan Tang et al.   Nature Communications

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease

(2017) Filippo Scialò et al.   Frontiers in Physiology

Hydrogels for therapeutic cardiovascular angiogenesis

(2016) Abdul Jalil Rufaihah et al.   ADVANCED DRUG DELIVERY REVIEWS

Decellularized myocardial matrix hydrogels: In basic research and preclinical studies

(2016) Raymond M. Wang et al.   ADVANCED DRUG DELIVERY REVIEWS

Progression in sensing cardiac troponin biomarker charge transductions on semiconducting nanomaterials

(2016) M.F.M. Fathil et al.   ANALYTICA CHIMICA ACTA

Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis

(2016) Laszlo Tretter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

(2016) Vicky Lampropoulou et al.   Cell Metabolism

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart FailureNovelty and Significance

(2016) Hendrik B. Sager et al.   CIRCULATION RESEARCH

Functional role of inorganic trace elements in angiogenesis part III: (Ti, Li, Ce, As, Hg, Va, Nb and Pb)

(2016) Mohammad Ali Saghiri et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Clearance of apoptotic neutrophils and resolution of inflammation

(2016) Mallary C. Greenlee-Wacker   IMMUNOLOGICAL REVIEWS

Selection of specific inhibitor peptides in enzyme-linked immunosorbent assay (ELISA) of cardiac troponin I using immuno-dominant epitopes as competitor

(2016) Majid Asiabanha Rezaee et al.   JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

(2016) Catherine E. Winbanks et al.   Science Translational Medicine

Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice

(2016) Vengadeshprabhu Karuppagounder et al.   PLoS One

Injectable gelatin derivative hydrogels with sustained vascular endothelial growth factor release for induced angiogenesis

(2015) Zhe Li et al.   Acta Biomaterialia

The Spectrum of Epidemiology Underlying Sudden Cardiac Death

(2015) M. Hayashi et al.   CIRCULATION RESEARCH

Sustained co-delivery of BIO and IGF-1 by a novel hybrid hydrogel system to stimulate endogenous cardiac repair in myocardial infarcted rat hearts

(2015) Rui Fang et al.   International Journal of Nanomedicine

Behind the Link between Copper and Angiogenesis: Established Mechanisms and an Overview on the Role of Vascular Copper Transport Systems

(2015) Emanuela Urso et al.   JOURNAL OF VASCULAR RESEARCH

Evaluation ofin vivocytogenetic toxicity of europium hydroxide nanorods (EHNs) in male and female Swiss albino mice

(2015) Vishnu Sravan Bollu et al.   Nanotoxicology

Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function

(2015) Gin-Fu Chen et al.   Scientific Reports

Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system

(2015) Zhongyuan Wang et al.   Scientific Reports

Ly-6C high Monocytes Depend on Nr4a1 to Balance Both Inflammatory and Reparative Phases in the Infarcted Myocardium

(2014) Ingo Hilgendorf et al.   CIRCULATION RESEARCH

Angiogenesis and Cardiac Hypertrophy

(2014) Toru Oka et al.   CIRCULATION RESEARCH

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Macrophage Activation: Glancing into Diversity

(2014) Gioacchino Natoli et al.   IMMUNITY

Nano-engineered mesenchymal stem cells as targeted therapeutic carriers

(2014) Tanmoy Sadhukha et al.   JOURNAL OF CONTROLLED RELEASE

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Dual-temperature and pH responsive (ethylene glycol)-based nanogels via structural design

(2014) Yohei Kotsuchibashi et al.   Polymer Chemistry

Novel aspects of ROS signalling in heart failure

(2013) Anne D. Hafstad et al.   BASIC RESEARCH IN CARDIOLOGY

The role of oxidative stress during inflammatory processes

(2013) Jérôme Lugrin et al.   BIOLOGICAL CHEMISTRY

Cerium Oxide Nanoparticles Protect Endothelial Cells from Apoptosis Induced by Oxidative Stress

(2013) Shizhu Chen et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

(2013) Elaine Wan et al.   CIRCULATION RESEARCH

Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure

(2013) Mohamed Ameen Ismahil et al.   CIRCULATION RESEARCH

Porcine carotid artery replacement with biodegradable electrospun poly-e-caprolactone vascular prosthesis

(2013) Wojciech Mrówczyński et al.   JOURNAL OF VASCULAR SURGERY

The induction of angiogenesis by cerium oxide nanoparticles through the modulation of oxygen in intracellular environments

(2012) Soumen Das et al.   BIOMATERIALS

How to use high-sensitivity cardiac troponins in acute cardiac care

(2012) K. Thygesen et al.   EUROPEAN HEART JOURNAL

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Catheter-Deliverable Hydrogel Derived From Decellularized Ventricular Extracellular Matrix Increases Endogenous Cardiomyocytes and Preserves Cardiac Function Post-Myocardial Infarction

(2012) Jennifer M. Singelyn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ultrahigh sensitivity assays for human cardiac troponin I using TiO2 nanotube arrays

(2012) Piyush Kar et al.   LAB ON A CHIP

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

Functional Supramolecular Polymers

(2012) T. Aida et al.   SCIENCE

A phosphate-dependent shift in redox state of cerium oxide nanoparticles and its effects on catalytic properties

(2011) Sanjay Singh et al.   BIOMATERIALS

GSK-3  regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1 

(2011) D. Flugel et al.   BLOOD

Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands

(2011) Chao Shi et al.   IMMUNITY

RNA sensor–induced type I IFN prevents diabetes caused by a β cell–tropic virus in mice

(2011) Stephen A. McCartney et al.   JOURNAL OF CLINICAL INVESTIGATION

Reactive Oxygen Species Driven Angiogenesis by Inorganic Nanorods

(2011) Chitta Ranjan Patra et al.   NANO LETTERS

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Shape Effect of Carbon Nanovectors on Angiogenesis

(2010) Padmaparna Chaudhuri et al.   ACS Nano

The inhibition of retinal neovascularization by gold nanoparticles via suppression of VEGFR-2 activation

(2010) Jin Hyoung Kim et al.   BIOMATERIALS

Electrospinning of PLGA/gelatin randomly-oriented and aligned nanofibers as potential scaffold in tissue engineering

(2010) Z.X. Meng et al.   Materials Science & Engineering C-Materials for Biological Applications

Mast cells contribute to altered vascular reactivity and ischemia-reperfusion injury following cerium oxide nanoparticle instillation

(2010) Christopher J. Wingard et al.   Nanotoxicology

Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering

(2009) Jennifer M. Singelyn et al.   BIOMATERIALS

Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody

(2009) Fatih Arslan et al.   CIRCULATION

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Pro-angiogenic Properties of Europium(III) Hydroxide Nanorods

(2008) C. R. Patra et al.   ADVANCED MATERIALS

Pioglitazone protects the myocardium against ischemia-reperfusion injury in eNOS and iNOS knockout mice

(2008) Yumei Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS