Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

Prevalence of Azole-Resistant Aspergillus fumigatus is Highly Associated with Azole Fungicide Residues in the Fields

(2021) Duantao Cao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Genomic Diversity of Azole-Resistant Aspergillus fumigatus in the United States

(2021) Kizee A. Etienne et al.   mBio

Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection

(2021) Amelia E. Barber et al.   Nature Microbiology

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

(2020) Takanori Furukawa et al.   Nature Communications

A novel combination of CYP51A mutations confers pan-azole resistance in Aspergillus fumigatus.

(2020) Daiana Macedo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Confronting and mitigating the risk of COVID-19 Associated Pulmonary Aspergillosis (CAPA)

(2020) Darius Armstrong-James et al.   EUROPEAN RESPIRATORY JOURNAL

On the lineage of Aspergillus fumigatus isolates in common laboratory use

(2020) Margherita Bertuzzi et al.   MEDICAL MYCOLOGY

Effects of Agricultural Fungicide Use on Aspergillus fumigatus Abundance, Antifungal Susceptibility, and Population Structure

(2020) Amelia E. Barber et al.   mBio

The one health problem of azole resistance in Aspergillus fumigatus: current insights and future research agenda

(2020) Paul E. Verweij et al.   Fungal Biology Reviews

Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus

(2019) Thomas R. Sewell et al.   mBio

A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen

(2019) Nicholas Raffa et al.   PLoS Pathogens

Elevated prevalence of azole resistant Aspergillus fumigatus in urban versus rural environments in the United Kingdom

(2019) Thomas R Sewell et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MARDy: Mycology Antifungal Resistance Database

(2018) Anthony Nash et al.   BIOINFORMATICS

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline

(2018) A.J. Ullmann et al.   CLINICAL MICROBIOLOGY AND INFECTION

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

(2018) Matthew C. Fisher et al.   SCIENCE

A phylogenetic method to perform genome-wide association studies in microbes that accounts for population structure and recombination

(2018) Caitlin Collins et al.   PLoS Computational Biology

Determination of the Prevalence of Triazole Resistance in Environmental Aspergillus fumigatus Strains Isolated in South Wales, UK

(2018) Alexandra Tsitsopoulou et al.   Frontiers in Microbiology

Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study

(2018) Alexander F A D Schauwvlieghe et al.   Lancet Respiratory Medicine

Aspf2 From Aspergillus fumigatus Recruits Human Immune Regulators for Immune Evasion and Cell Damage

(2018) Prasad Dasari et al.   Frontiers in Immunology

Voriconazole Resistance and Mortality in Invasive Aspergillosis: A Multicenter Retrospective Cohort Study

(2018) Pieter P Lestrade et al.   CLINICAL INFECTIOUS DISEASES

OrthoDB v10: sampling the diversity of animal, plant, fungal, protist, bacterial and viral genomes for evolutionary and functional annotations of orthologs

(2018) Evgenia V Kriventseva et al.   NUCLEIC ACIDS RESEARCH

First itraconazole resistant Aspergillus fumigatus clinical isolate harbouring a G54E substitution in Cyp51Ap in South America

(2017) Florencia Leonardelli et al.   REVISTA IBEROAMERICANA DE MICOLOGIA

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

(2017) Jianhua Zhang et al.   mBio

Azole-resistant Aspergillus fumigatus harboring TR34/L98H, TR46/Y121F/T289A and TR53 mutations related to flower fields in Colombia

(2017) Carlos Alvarez-Moreno et al.   Scientific Reports

Emerging aspergillosis by azole-resistantAspergillus fumigatusat an intensive care unit in the Netherlands, 2010 to 2013

(2016) Judith van Paassen et al.   Eurosurveillance

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(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

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(2015) Dinghua Li et al.   BIOINFORMATICS

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(2015) Lars Snipen et al.   BMC BIOINFORMATICS

Within-host nucleotide diversity of virus populations: Insights from next-generation sequencing

(2015) Chase W. Nelson et al.   INFECTION GENETICS AND EVOLUTION

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States

(2015) Nathan P. Wiederhold et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Dfam database of repetitive DNA families

(2015) Robert Hubley et al.   NUCLEIC ACIDS RESEARCH

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(2014) Anthony M. Bolger et al.   BIOINFORMATICS

The role of azoles in the management of azole-resistant aspergillosis: From the bench to the bedside

(2014) Seyedmojtaba Seyedmousavi et al.   DRUG RESISTANCE UPDATES

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(2014) Benjamin Buchfink et al.   NATURE METHODS

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(2014) R.A. Samson et al.   STUDIES IN MYCOLOGY

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Aspergillosis due to Voriconazole Highly Resistant Aspergillus fumigatus and Recovery of Genetically Related Resistant Isolates From Domiciles

(2013) Jan W. M. van der Linden et al.   CLINICAL INFECTIOUS DISEASES

Novel immunologic classification of aspergillosis in adult cystic fibrosis

(2013) Caroline G. Baxter et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

EUCAST Technical Note on Aspergillus and amphotericin B, itraconazole, and posaconazole

(2012) M.C. Arendrup et al.   CLINICAL MICROBIOLOGY AND INFECTION

Molecular Epidemiology of Aspergillus fumigatus Isolates Harboring the TR34/L98H Azole Resistance Mechanism

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Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study

(2012) Timothy M Walker et al.   LANCET INFECTIOUS DISEASES

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(2012) Derrick E. Fouts et al.   NUCLEIC ACIDS RESEARCH

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Inference of Population Structure using Dense Haplotype Data

(2012) Daniel John Lawson et al.   PLoS Genetics

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(2011) P. Danecek et al.   BIOINFORMATICS

adegenet 1.3-1: new tools for the analysis of genome-wide SNP data

(2011) Thibaut Jombart et al.   BIOINFORMATICS

Evidence for genetic differentiation and variable recombination rates among Dutch populations of the opportunistic human pathogenAspergillus fumigatus

(2011) CORNÉ H. W. KLAASSEN et al.   MOLECULAR ECOLOGY

Discriminant analysis of principal components: a new method for the analysis of genetically structured populations

(2010) Thibaut Jombart et al.   BMC GENETICS

The Transposon impala Is Activated by Low Temperatures: Use of a Controlled Transposition System To Identify Genes Critical for Viability of Aspergillus fumigatus

(2010) Paul D. Carr et al.   EUKARYOTIC CELL

Differential inhibition of murine Bcrp1/Abcg2 and human BCRP/ABCG2 by the mycotoxin fumitremorgin C

(2010) Lucía González-Lobato et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Development of Azole Resistance in Aspergillus fumigatus during Azole Therapy Associated with Change in Virulence

(2010) Maiken Cavling Arendrup et al.   PLoS One

Possible Environmental Origin of Resistance of Aspergillus fumigatus to Medical Triazoles

(2009) E. Snelders et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

(2009) Paul E Verweij et al.   LANCET INFECTIOUS DISEASES

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols